Guardant Health (GH) Operating Expenses (2017 - 2026)
Guardant Health's (GH) quarterly Operating Expenses came in at $423.0 million in Q1 2026, up 34.5% year-on-year from $314.5 million in Q1 2025, and up 5.21% quarter-over-quarter from $402.1 million in Q4 2025.
Guardant Health (GH) Operating Expenses (2017 - 2026) Analysis & Trends
Guardant Health has disclosed Operating Expenses across 10 years of filings, most recently posting $423.0 million for Q1 2026.
- Operating Expenses for Q1 2026 came in at $423.0 million, up 34.5% year-over-year; the trailing twelve-month figure through Mar 2026 was $1.5 billion (up 24.32% YoY), and the FY2025 annual result was $1.4 billion, up 20.01% from the prior year.
- Operating Expenses came in at $423.0 million for Q1 2026 at Guardant Health, up from $402.1 million in the prior quarter.
- In the past five years, Operating Expenses ranged from a high of $423.0 million in Q1 2026 to a low of $219.4 million in Q1 2022.
- The 5-year median for Operating Expenses is $277.9 million (2024), against an average of $302.8 million.
- Across the five-year window, Operating Expenses declined 7.03% in 2024 and jumped 34.5% in 2026, its largest moves.
- Guardant Health's Operating Expenses stood at $273.0 million in 2022, then climbed by 29.14% to $352.6 million in 2023, then declined by 7.03% to $327.8 million in 2024, then advanced by 22.67% to $402.1 million in 2025, then advanced by 5.21% to $423.0 million in 2026.
- The last three Operating Expenses figures came in at $423.0 million (Q1 2026), $402.1 million (Q4 2025), and $364.2 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | 1.31 Bn |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 9.14 Bn |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 2.25 Bn |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 360.15 Mn |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 1.44 Bn |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 553.00 Mn |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | 790.16 Mn |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 512.00 Mn |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 316.87 Mn |
| 10 | Guardant Health | 16.38 Bn | 15.28 Bn | 196.75 Mn | 423.02 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 423.02 Mn |
| Dec 31, 2025 | 402.07 Mn |
| Sep 30, 2025 | 364.19 Mn |
| Jun 30, 2025 | 338.50 Mn |
| Mar 31, 2025 | 314.51 Mn |
| Dec 31, 2024 | 327.78 Mn |
| Sep 30, 2024 | 308.80 Mn |
| Jun 30, 2024 | 277.85 Mn |
| Mar 31, 2024 | 268.17 Mn |
| Dec 31, 2023 | 352.57 Mn |
| Sep 30, 2023 | 256.57 Mn |
| Jun 30, 2023 | 256.77 Mn |
| Mar 31, 2023 | 262.77 Mn |
| Dec 31, 2022 | 273.01 Mn |
| Sep 30, 2022 | 262.00 Mn |
| Jun 30, 2022 | 239.47 Mn |
| Mar 31, 2022 | 219.44 Mn |
| Dec 31, 2021 | 206.32 Mn |
| Sep 30, 2021 | 202.07 Mn |
| Jun 30, 2021 | 189.74 Mn |