Guardant Health (GH) Operating Expenses (2017 - 2026)

Guardant Health (GH) posted Operating Expenses of $423.0 million for Q1 2026, up 5.21% sequentially from $402.1 million in Q4 2025, and up 34.5% YoY from $314.5 million in Q1 2025.

Guardant Health (GH) Operating Expenses (2017 - 2026) Analysis & Trends

Guardant Health (GH) has 10 years of Operating Expenses data on file, last reported at $423.0 million in Q1 2026.

  • Quarterly Operating Expenses rose 34.5% year-over-year to $423.0 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $1.5 billion (up 24.32% YoY) and the FY2025 annual result came in at $1.4 billion, up 20.01% from the prior year.
  • Operating Expenses rose to $423.0 million in Q1 2026 per GH's latest filing, from $402.1 million in the prior quarter.
  • The five-year high for Operating Expenses was $423.0 million in Q1 2026, with the low at $219.4 million in Q1 2022.
  • Average Operating Expenses over 5 years is $302.8 million, with a median of $277.9 million recorded in 2024.
  • Year-over-year, Operating Expenses slipped 7.03% in 2024 and surged 34.5% in 2026.
  • Guardant Health's Operating Expenses stood at $273.0 million in 2022, then rose by 29.14% to $352.6 million in 2023, then decreased by 7.03% to $327.8 million in 2024, then increased by 22.67% to $402.1 million in 2025, then increased by 5.21% to $423.0 million in 2026.
  • Business Quant data shows GH's Operating Expenses at $423.0 million in Q1 2026, $402.1 million in Q4 2025, and $364.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn 1.31 Bn
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn 9.14 Bn
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn 2.25 Bn
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn 360.15 Mn
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn 790.16 Mn
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn 1.44 Bn
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn 553.00 Mn
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn 512.00 Mn
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn 316.87 Mn
10 Guardant Health 22.42 Bn 21.31 Bn 196.75 Mn 423.02 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 423.02 Mn
Dec 31, 2025 402.07 Mn
Sep 30, 2025 364.19 Mn
Jun 30, 2025 338.50 Mn
Mar 31, 2025 314.51 Mn
Dec 31, 2024 327.78 Mn
Sep 30, 2024 308.80 Mn
Jun 30, 2024 277.85 Mn
Mar 31, 2024 268.17 Mn
Dec 31, 2023 352.57 Mn
Sep 30, 2023 256.57 Mn
Jun 30, 2023 256.77 Mn
Mar 31, 2023 262.77 Mn
Dec 31, 2022 273.01 Mn
Sep 30, 2022 262.00 Mn
Jun 30, 2022 239.47 Mn
Mar 31, 2022 219.44 Mn
Dec 31, 2021 206.32 Mn
Sep 30, 2021 202.07 Mn
Jun 30, 2021 189.74 Mn