Guardant Health (GH) Operating Expenses (2017 - 2026)

Guardant Health's (GH) quarterly Operating Expenses came in at $423.0 million in Q1 2026, up 34.5% year-on-year from $314.5 million in Q1 2025, and up 5.21% quarter-over-quarter from $402.1 million in Q4 2025.

Guardant Health (GH) Operating Expenses (2017 - 2026) Analysis & Trends

Guardant Health has disclosed Operating Expenses across 10 years of filings, most recently posting $423.0 million for Q1 2026.

  • Operating Expenses for Q1 2026 came in at $423.0 million, up 34.5% year-over-year; the trailing twelve-month figure through Mar 2026 was $1.5 billion (up 24.32% YoY), and the FY2025 annual result was $1.4 billion, up 20.01% from the prior year.
  • Operating Expenses came in at $423.0 million for Q1 2026 at Guardant Health, up from $402.1 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $423.0 million in Q1 2026 to a low of $219.4 million in Q1 2022.
  • The 5-year median for Operating Expenses is $277.9 million (2024), against an average of $302.8 million.
  • Across the five-year window, Operating Expenses declined 7.03% in 2024 and jumped 34.5% in 2026, its largest moves.
  • Guardant Health's Operating Expenses stood at $273.0 million in 2022, then climbed by 29.14% to $352.6 million in 2023, then declined by 7.03% to $327.8 million in 2024, then advanced by 22.67% to $402.1 million in 2025, then advanced by 5.21% to $423.0 million in 2026.
  • The last three Operating Expenses figures came in at $423.0 million (Q1 2026), $402.1 million (Q4 2025), and $364.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn 1.31 Bn
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 9.14 Bn
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 2.25 Bn
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 360.15 Mn
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 1.44 Bn
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 553.00 Mn
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn 790.16 Mn
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 512.00 Mn
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 316.87 Mn
10 Guardant Health 16.38 Bn 15.28 Bn 196.75 Mn 423.02 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 423.02 Mn
Dec 31, 2025 402.07 Mn
Sep 30, 2025 364.19 Mn
Jun 30, 2025 338.50 Mn
Mar 31, 2025 314.51 Mn
Dec 31, 2024 327.78 Mn
Sep 30, 2024 308.80 Mn
Jun 30, 2024 277.85 Mn
Mar 31, 2024 268.17 Mn
Dec 31, 2023 352.57 Mn
Sep 30, 2023 256.57 Mn
Jun 30, 2023 256.77 Mn
Mar 31, 2023 262.77 Mn
Dec 31, 2022 273.01 Mn
Sep 30, 2022 262.00 Mn
Jun 30, 2022 239.47 Mn
Mar 31, 2022 219.44 Mn
Dec 31, 2021 206.32 Mn
Sep 30, 2021 202.07 Mn
Jun 30, 2021 189.74 Mn