Personalis (PSNL) Net Margin (2018 - 2026)
Personalis (PSNL) recorded Net Margin of -141.71% in Q2 2026, down 25.13 percentage points from -116.58% a year earlier but up 52.39 percentage points from the prior quarter.
Powered by 
Analysis
Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends
On a TTM basis, Personalis' Net Margin came in at -153.84% as of Jun 30, 2026, down 40.14 percentage points year-over-year; for FY2025, it was -116.69%, down 20.62 percentage points from FY2024.
- Annual Net Margin has a five-year change of -64.20 percentage points (FY2020 to FY2025).
- Across earlier years, Net Margin came in at -96.06% in FY2024 (+51.32 pp), -147.38% in FY2023 (+26.83 pp), -174.20% in FY2022 (-97.91 pp) and -76.29% in FY2021 (-23.81 pp).
- Quarterly Net Margin has ranged from -194.11% in Q1 2026 to -56.70% in Q2 2024 over the past five years.
- On a year-over-year basis, Net Margin has declined for three consecutive quarters, with an average year-over-year change of -25.60 percentage points over the last eight quarters.
- Peak year-over-year performance for Net Margin in the last five years was a gain of 86.76 percentage points in Q2 2024, against a drop of 125.85 percentage points in Q1 2022 at the low end.
- Per Business Quant, the preceding three quarters came in at -194.11% (Q1 2026), -137.28% (Q4 2025) and -149.38% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 101.22 Bn | 97.23 Bn | - | 8.40% |
| 2 | Natera | 59.29 Bn | 54.98 Bn | 485.19 Mn | -8.90% |
| 3 | Quest Diagnostics | 26.56 Bn | 24.69 Bn | 1.03 Bn | 10.52% |
| 4 | Labcorp Holdings | 26.41 Bn | 24.16 Bn | 1.11 Bn | 8.01% |
| 5 | Tenet Healthcare | 22.49 Bn | 11.49 Bn | - | 14.68% |
| 6 | Guardant Health | 22.12 Bn | 18.19 Bn | 219.03 Mn | -35.87% |
| 7 | BrightSpring Health Services | 12.91 Bn | 11.24 Bn | 492.75 Mn | 2.18% |
| 8 | Fresenius Medical Care AG | 12.56 Bn | 4.51 Bn | 1.52 Bn | 4.49% |
| 9 | Tempus AI | 12.17 Bn | 9.20 Bn | 246.50 Mn | 1.48% |
| 10 | Personalis | 1.68 Bn | 845.71 Mn | 4.74 Mn | -141.71% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -141.71% |
| Mar 31, 2026 | -194.11% |
| Dec 31, 2025 | -137.28% |
| Sep 30, 2025 | -149.38% |
| Jun 30, 2025 | -116.58% |
| Mar 31, 2025 | -76.44% |
| Dec 31, 2024 | -97.77% |
| Sep 30, 2024 | -152.04% |
| Jun 30, 2024 | -56.70% |
| Mar 31, 2024 | -66.42% |
| Dec 31, 2023 | -135.12% |
| Sep 30, 2023 | -159.47% |
| Jun 30, 2023 | -143.45% |
| Mar 31, 2023 | -151.96% |
| Dec 31, 2022 | -185.79% |
| Sep 30, 2022 | -178.30% |
| Jun 30, 2022 | -151.02% |
| Mar 31, 2022 | -185.26% |
| Dec 31, 2021 | -97.66% |
| Sep 30, 2021 | -79.38% |
API Access
Personalis Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();