Personalis (PSNL) Net Margin (2018 - 2026)
Personalis (PSNL) recorded quarterly Net Margin of 194.11% in Q1 2026, down 158.53% quarter-over-quarter from 331.63% in Q4 2025, and down 11767.0% on a YoY basis from N/an in Q1 2025.
Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends
Personalis' Net Margin history runs 9 years deep, the most recent figure standing at 194.11% for Q1 2026.
- In Q1 2026, Net Margin fell 11767.0% year-over-year to 194.11%; the TTM figure through Mar 2026 stood at 22.04% (up 7606.0% YoY), while the FY2025 annual figure was 0.09%, up 9615.0% from the prior year.
- Net Margin was 194.11% for Q1 2026 at Personalis, down from 331.63% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 493.3% in Q4 2022 to a low of 194.11% in Q1 2026.
- Historically, Net Margin has averaged 69.95% across 5 years, with a median of 143.45% in 2023.
- The sharpest annual moves came in 2022 and 2023: Net Margin jumped 59209 bps in 2022, then tumbled 62842 bps in 2023.
- A 5-year view of Net Margin shows it stood at 493.3% in 2022, then tumbled by 127 bps to 135.12% in 2023, then grew by 28 bps to 97.77% in 2024, then soared by 439 bps to 331.63% in 2025, then tumbled by 159 bps to 194.11% in 2026.
- The last three Net Margin figures came in at 194.11% (Q1 2026), 331.63% (Q4 2025), and 149.38% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 30,529.42 Bn | 30,528.96 Bn | 1.11 Bn | -5.68% |
| 2 | Thermo Fisher Scientific | 183.75 Bn | 180.50 Bn | 7.74 Bn | 15.06% |
| 3 | Danaher | 133.13 Bn | 127.43 Bn | 3.59 Bn | 17.29% |
| 4 | Idexx Laboratories | 46.14 Bn | 45.94 Bn | 722.74 Mn | 24.41% |
| 5 | Agilent Technologies | 38.20 Bn | 36.39 Bn | 990.00 Mn | 18.47% |
| 6 | Natera | 31.50 Bn | 30.40 Bn | 696.04 Mn | -12.22% |
| 7 | Iqvia Holdings | 31.34 Bn | 29.36 Bn | 1.36 Bn | 3.40% |
| 8 | Illumina | 24.51 Bn | 23.36 Bn | 721.00 Mn | 12.28% |
| 9 | Mettler Toledo International | 23.53 Bn | 23.47 Bn | 555.82 Mn | 17.89% |
| 10 | Personalis | 1.01 Bn | 780.57 Mn | 281,000.00 | -194.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -194.11% |
| Dec 31, 2025 | 331.63% |
| Sep 30, 2025 | -149.38% |
| Jun 30, 2025 | -116.58% |
| Mar 31, 2025 | -76.44% |
| Dec 31, 2024 | -97.77% |
| Sep 30, 2024 | -152.04% |
| Jun 30, 2024 | -56.70% |
| Mar 31, 2024 | -66.42% |
| Dec 31, 2023 | -135.12% |
| Sep 30, 2023 | -159.47% |
| Jun 30, 2023 | -143.45% |
| Mar 31, 2023 | -151.96% |
| Dec 31, 2022 | 493.30% |
| Sep 30, 2022 | -178.30% |
| Jun 30, 2022 | -151.02% |
| Mar 31, 2022 | -185.26% |
| Dec 31, 2021 | -98.79% |
| Sep 30, 2021 | -79.38% |
| Jun 30, 2021 | -69.00% |