Growth Metrics

Personalis (PSNL) Net Margin (2018 - 2025)

Personalis has reported Net Margin over the past 8 years, most recently at 137.65% for Q4 2025.

  • Quarterly results put Net Margin at 137.65% for Q4 2025, down 3999.0% from a year ago — trailing twelve months through Dec 2025 was 116.78% (down 2073.0% YoY), and the annual figure for FY2025 was 116.78%, down 2073.0%.
  • Net Margin for Q4 2025 was 137.65% at Personalis, up from 149.38% in the prior quarter.
  • Over the last five years, Net Margin for PSNL hit a ceiling of 493.3% in Q4 2022 and a floor of 185.26% in Q1 2022.
  • Median Net Margin over the past 5 years was 125.85% (2023), compared with a mean of 88.48%.
  • Biggest five-year swings in Net Margin: soared 59097bps in 2022 and later tumbled -62842bps in 2023.
  • Personalis' Net Margin stood at 97.66% in 2021, then skyrocketed by 605bps to 493.3% in 2022, then tumbled by -127bps to 135.12% in 2023, then grew by 28bps to 97.66% in 2024, then tumbled by -41bps to 137.65% in 2025.
  • The last three reported values for Net Margin were 137.65% (Q4 2025), 149.38% (Q3 2025), and 116.58% (Q2 2025) per Business Quant data.