Personalis (PSNL) Net Margin (2018 - 2026)
Personalis (PSNL) posted quarterly Net Margin of 194.11% for Q1 2026, down 11767.0% year-over-year from N/an in Q1 2025, and down 158.53% on a QoQ basis from 331.63% in Q4 2025.
Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends
Personalis (PSNL) has reported Net Margin for 9 consecutive years, with 194.11% the latest figure, recorded in Q1 2026.
- In Q1 2026, Net Margin fell 11767.0% year-over-year to 194.11%; the TTM figure through Mar 2026 stood at 22.04% (up 7606.0% YoY), while the FY2025 annual figure was 0.09%, up 9615.0% from the prior year.
- Net Margin came in at 194.11% for Q1 2026 at Personalis, down from 331.63% in the prior quarter.
- The five-year high for Net Margin was 493.3% in Q4 2022, with the low at 194.11% in Q1 2026.
- Average Net Margin over 5 years is 69.95%, with a median of 143.45% recorded in 2023.
- Across the five-year window, Net Margin jumped 59209 bps in 2022 and plunged 62842 bps in 2023, its largest moves.
- Year by year, Net Margin stood at 493.3% in 2022, then plunged by 127 bps to 135.12% in 2023, then gained by 28 bps to 97.77% in 2024, then soared by 439 bps to 331.63% in 2025, then plunged by 159 bps to 194.11% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 194.11%, 331.63%, and 149.38% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -5.68% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 15.06% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 17.29% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 24.41% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -12.22% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 18.47% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 3.40% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 12.28% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 17.89% |
| 10 | Personalis | 1.44 Bn | 1.20 Bn | 281,000.00 | -194.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -194.11% |
| Dec 31, 2025 | 331.63% |
| Sep 30, 2025 | -149.38% |
| Jun 30, 2025 | -116.58% |
| Mar 31, 2025 | -76.44% |
| Dec 31, 2024 | -97.77% |
| Sep 30, 2024 | -152.04% |
| Jun 30, 2024 | -56.70% |
| Mar 31, 2024 | -66.42% |
| Dec 31, 2023 | -135.12% |
| Sep 30, 2023 | -159.47% |
| Jun 30, 2023 | -143.45% |
| Mar 31, 2023 | -151.96% |
| Dec 31, 2022 | 493.30% |
| Sep 30, 2022 | -178.30% |
| Jun 30, 2022 | -151.02% |
| Mar 31, 2022 | -185.26% |
| Dec 31, 2021 | -98.79% |
| Sep 30, 2021 | -79.38% |
| Jun 30, 2021 | -69.00% |