Personalis (PSNL) Net Margin (2018 - 2026)
Personalis (PSNL) posted quarterly Net Margin of 194.11% for Q1 2026, down 11767.0% year-over-year from N/an in Q1 2025, and down 41.14% quarter-over-quarter from 137.53% in Q4 2025.
Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends
Personalis' Net Margin history runs 9 years deep, the most recent figure standing at 194.11% for Q1 2026.
- In Q1 2026, Net Margin fell 11767.0% year-over-year to 194.11%; the TTM figure through Mar 2026 stood at 148.17% (down 7001.0% YoY), while the FY2025 annual figure was 116.75%, down 4087.0% from the prior year.
- Net Margin for Q1 2026 stood at 194.11%, down from 137.53% in the prior quarter.
- The five-year high for Net Margin was 408.15% in Q4 2023, with the low at 194.11% in Q1 2026.
- The 5-year median for Net Margin is 149.38% (2025), against an average of 99.56%.
- The sharpest annual moves came in 2022 and 2023: Net Margin sank 40460 bps in 2022, then jumped 59412 bps in 2023.
- Personalis' Net Margin stood at 185.98% in 2022, then soared by 319 bps to 408.15% in 2023, then tumbled by 99 bps to 3.92% in 2024, then sank by 3606 bps to 137.53% in 2025, then plunged by 41 bps to 194.11% in 2026.
- Business Quant data shows PSNL's Net Margin at 194.11% in Q1 2026, 137.53% in Q4 2025, and 149.38% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 14.65% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 13.89% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 27.82% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 18.47% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 5.52% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | -12.22% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 17.86% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 22.67% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 10.65% |
| 10 | Personalis | 1.40 Bn | 1.17 Bn | 281,000.00 | -194.11% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -194.11% |
| Dec 31, 2025 | -137.53% |
| Sep 30, 2025 | -149.38% |
| Jun 30, 2025 | -116.58% |
| Mar 31, 2025 | -76.44% |
| Dec 31, 2024 | 3.92% |
| Sep 30, 2024 | -152.04% |
| Jun 30, 2024 | -56.70% |
| Mar 31, 2024 | -66.42% |
| Dec 31, 2023 | 408.15% |
| Sep 30, 2023 | -159.47% |
| Jun 30, 2023 | -143.45% |
| Mar 31, 2023 | -151.96% |
| Dec 31, 2022 | -185.98% |
| Sep 30, 2022 | -178.30% |
| Jun 30, 2022 | -151.02% |
| Mar 31, 2022 | -185.26% |
| Dec 31, 2021 | 218.62% |
| Sep 30, 2021 | -79.38% |
| Jun 30, 2021 | -69.00% |