Personalis (PSNL) Net Margin (2018 - 2026)
Personalis (PSNL) posted Net Margin of 141.71% for Q2 2026, up 26.99% on a QoQ basis from 194.11% in Q1 2026, and down 2513.0% year-over-year from 5.87% in Q2 2025.
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Analysis
Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends
Personalis has reported Net Margin for 9 years, with the latest figure at 141.71% in Q2 2026.
- On a quarterly basis, Net Margin fell 2513.0% year-over-year to 141.71% in Q2 2026; TTM through Jun 2026 was 129.41%, a 3692.0% decrease from a year earlier, with the FY2025 full-year figure at 92.25%, down 1632.0% from the prior year.
- Net Margin was 141.71% for Q2 2026 at Personalis, up from 194.11% in the prior quarter.
- The five-year high for Net Margin was 3.65% in Q4 2024, with the low at 194.11% in Q1 2026.
- Average Net Margin over 5 years is 126.73%, with a median of 146.41% recorded in 2023.
- The sharpest annual moves came in 2022 and 2024: Net Margin tumbled 12585 bps in 2022, then surged 13876 bps in 2024.
- Over 5 years, Net Margin stood at 187.67% in 2022, then climbed by 28 bps to 135.12% in 2023, then jumped by 103 bps to 3.65% in 2024, then plunged by 1173 bps to 39.16% in 2025, then slumped by 262 bps to 141.71% in 2026.
- The last three Net Margin figures came in at 141.71% (Q2 2026), 194.11% (Q1 2026), and 39.16% (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Natera | 53.05 Bn | 51.95 Bn | 486.15 Mn | -8.89% |
| 2 | Quest Diagnostics | 27.19 Bn | 26.87 Bn | 1.03 Bn | 10.65% |
| 3 | Labcorp Holdings | 25.93 Bn | 25.81 Bn | 1.11 Bn | 8.02% |
| 4 | Guardant Health | 23.97 Bn | 22.91 Bn | 219.03 Mn | -35.87% |
| 5 | Tempus AI | 13.64 Bn | 12.82 Bn | 274.25 Mn | 2.22% |
| 6 | Caris Life Sciences | 8.47 Bn | 7.68 Bn | 182.38 Mn | -0.24% |
| 7 | Sotera Health | 5.35 Bn | 4.99 Bn | 177.96 Mn | 16.69% |
| 8 | BillionToOne | 4.96 Bn | 4.41 Bn | 77.11 Mn | 7.36% |
| 9 | Adaptive Biotechnologies | 4.55 Bn | 4.21 Bn | 51.39 Mn | -22.65% |
| 10 | Personalis | 1.74 Bn | 1.53 Bn | 4.74 Mn | -141.71% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -141.71% |
| Mar 31, 2026 | -194.11% |
| Dec 31, 2025 | -39.16% |
| Sep 30, 2025 | -149.38% |
| Jun 30, 2025 | -116.58% |
| Mar 31, 2025 | -76.44% |
| Dec 31, 2024 | 3.65% |
| Sep 30, 2024 | -152.04% |
| Jun 30, 2024 | -56.70% |
| Mar 31, 2024 | -66.42% |
| Dec 31, 2023 | -135.12% |
| Sep 30, 2023 | -159.47% |
| Jun 30, 2023 | -143.45% |
| Mar 31, 2023 | -151.96% |
| Dec 31, 2022 | -187.67% |
| Sep 30, 2022 | -178.30% |
| Jun 30, 2022 | -151.02% |
| Mar 31, 2022 | -185.26% |
| Dec 31, 2021 | -98.79% |
| Sep 30, 2021 | -79.38% |
API Access
Personalis Net Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=net-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "net-margin", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=net-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();