Personalis (PSNL) Net Margin (2018 - 2026)

Personalis (PSNL) posted quarterly Net Margin of 194.11% for Q1 2026, down 11767.0% year-over-year from N/an in Q1 2025, and down 158.53% on a QoQ basis from 331.63% in Q4 2025.

Personalis (PSNL) Net Margin (2018 - 2026) Analysis & Trends

Personalis (PSNL) has reported Net Margin for 9 consecutive years, with 194.11% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Net Margin fell 11767.0% year-over-year to 194.11%; the TTM figure through Mar 2026 stood at 22.04% (up 7606.0% YoY), while the FY2025 annual figure was 0.09%, up 9615.0% from the prior year.
  • Net Margin came in at 194.11% for Q1 2026 at Personalis, down from 331.63% in the prior quarter.
  • The five-year high for Net Margin was 493.3% in Q4 2022, with the low at 194.11% in Q1 2026.
  • Average Net Margin over 5 years is 69.95%, with a median of 143.45% recorded in 2023.
  • Across the five-year window, Net Margin jumped 59209 bps in 2022 and plunged 62842 bps in 2023, its largest moves.
  • Year by year, Net Margin stood at 493.3% in 2022, then plunged by 127 bps to 135.12% in 2023, then gained by 28 bps to 97.77% in 2024, then soared by 439 bps to 331.63% in 2025, then plunged by 159 bps to 194.11% in 2026.
  • According to Business Quant data, Net Margin over the past three periods registered 194.11%, 331.63%, and 149.38% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn -5.68%
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn 15.06%
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn 17.29%
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn 24.41%
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn -12.22%
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn 18.47%
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn 3.40%
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn 12.28%
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn 17.89%
10 Personalis 1.44 Bn 1.20 Bn 281,000.00 -194.11%

Historic Data

Download Data
DateValue
Mar 31, 2026 -194.11%
Dec 31, 2025 331.63%
Sep 30, 2025 -149.38%
Jun 30, 2025 -116.58%
Mar 31, 2025 -76.44%
Dec 31, 2024 -97.77%
Sep 30, 2024 -152.04%
Jun 30, 2024 -56.70%
Mar 31, 2024 -66.42%
Dec 31, 2023 -135.12%
Sep 30, 2023 -159.47%
Jun 30, 2023 -143.45%
Mar 31, 2023 -151.96%
Dec 31, 2022 493.30%
Sep 30, 2022 -178.30%
Jun 30, 2022 -151.02%
Mar 31, 2022 -185.26%
Dec 31, 2021 -98.79%
Sep 30, 2021 -79.38%
Jun 30, 2021 -69.00%