Growth Metrics

Personalis (PSNL) Net Margin (2018 - 2026)

Personalis has reported Net Margin over the past 8 years, most recently at 137.3% for Q4 2025.

  • For Q4 2025, Net Margin fell 52353.0% year-over-year to 137.3%; the TTM value through Dec 2025 reached 116.69%, down 11672.0%, while the annual FY2025 figure was 116.69%, 11672.0% down from the prior year.
  • Net Margin for Q4 2025 was 137.3% at Personalis, up from 149.38% in the prior quarter.
  • Over five years, Net Margin peaked at 493.12% in Q4 2022 and troughed at 185.26% in Q1 2022.
  • A 5-year average of 64.27% and a median of 125.71% in 2023 define the central range for Net Margin.
  • Biggest five-year swings in Net Margin: soared 59092bps in 2022 and later plummeted -62796bps in 2023.
  • Year by year, Net Margin stood at 97.8% in 2021, then soared by 604bps to 493.12% in 2022, then crashed by -127bps to 134.84% in 2023, then surged by 386bps to 386.23% in 2024, then plummeted by -136bps to 137.3% in 2025.
  • Business Quant data shows Net Margin for PSNL at 137.3% in Q4 2025, 149.38% in Q3 2025, and 116.58% in Q2 2025.