Growth Metrics

Guardant Health (GH) Net Margin (2017 - 2025)

Guardant Health's Net Margin history spans 9 years, with the latest figure at 45.68% for Q4 2025.

  • For Q4 2025, Net Margin rose 932.0% year-over-year to 45.68%; the TTM value through Dec 2025 reached 42.39%, up 1666.0%, while the annual FY2025 figure was 42.39%, 1666.0% up from the prior year.
  • Net Margin for Q4 2025 was 45.68% at Guardant Health, down from 34.96% in the prior quarter.
  • Across five years, Net Margin topped out at 34.96% in Q3 2025 and bottomed at 210.21% in Q2 2022.
  • The 5-year median for Net Margin is 76.17% (2024), against an average of 88.76%.
  • The largest annual shift saw Net Margin plummeted -10427bps in 2022 before it soared 15715bps in 2023.
  • A 5-year view of Net Margin shows it stood at 84.09% in 2021, then crashed by -31bps to 110.28% in 2022, then dropped by -9bps to 120.63% in 2023, then surged by 54bps to 55.0% in 2024, then increased by 17bps to 45.68% in 2025.
  • Per Business Quant, the three most recent readings for GH's Net Margin are 45.68% (Q4 2025), 34.96% (Q3 2025), and 43.04% (Q2 2025).