Guardant Health (GH) Net Margin (2017 - 2026)

Guardant Health's (GH) quarterly Net Margin came in at 37.15% in Q1 2026, up 962.0% year-on-year from 3.5% in Q1 2025, and up 18.68% quarter-over-quarter from 45.68% in Q4 2025.

Guardant Health (GH) Net Margin (2017 - 2026) Analysis & Trends

Guardant Health has disclosed Net Margin across 10 years of filings, most recently posting 37.15% for Q1 2026.

  • Net Margin for Q1 2026 came in at 37.15%, up 962.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 40.1% (up 1372.0% YoY), and the FY2025 annual result was 42.39%, up 1666.0% from the prior year.
  • Net Margin came in at 37.15% for Q1 2026 at Guardant Health, up from 45.68% in the prior quarter.
  • In the past five years, Net Margin ranged from a high of 34.96% in Q3 2025 to a low of 210.21% in Q2 2022.
  • The 5-year median for Net Margin is 57.91% (2024), against an average of 80.55%.
  • Across the five-year window, Net Margin plunged 10427 bps in 2022 and surged 15715 bps in 2023, its largest moves.
  • Guardant Health's Net Margin stood at 110.28% in 2022, then fell by 9 bps to 120.63% in 2023, then jumped by 54 bps to 55.0% in 2024, then gained by 17 bps to 45.68% in 2025, then gained by 19 bps to 37.15% in 2026.
  • The last three Net Margin figures came in at 37.15% (Q1 2026), 45.68% (Q4 2025), and 34.96% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn -5.68%
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 15.06%
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 17.29%
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 24.41%
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 18.47%
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 3.40%
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn -12.22%
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 12.28%
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 17.89%
10 Guardant Health 16.38 Bn 15.28 Bn 196.75 Mn -37.15%

Historic Data

Download Data
DateValue
Mar 31, 2026 -37.15%
Dec 31, 2025 -45.68%
Sep 30, 2025 -34.96%
Jun 30, 2025 -43.04%
Mar 31, 2025 -46.77%
Dec 31, 2024 -55.00%
Sep 30, 2024 -56.28%
Jun 30, 2024 -57.91%
Mar 31, 2024 -68.24%
Dec 31, 2023 -120.63%
Sep 30, 2023 -60.20%
Jun 30, 2023 -53.06%
Mar 31, 2023 -103.74%
Dec 31, 2022 -110.28%
Sep 30, 2022 -137.98%
Jun 30, 2022 -210.21%
Mar 31, 2022 -128.23%
Dec 31, 2021 -84.09%
Sep 30, 2021 -113.45%
Jun 30, 2021 -105.94%