Personalis (PSNL) Gross Margin (2018 - 2026)

Personalis (PSNL) posted quarterly Gross Margin of 1.82% for Q1 2026, down 3316.0% year-over-year from 0.06% in Q1 2025, and down 83.42% quarter-over-quarter from 10.95% in Q4 2025.

Personalis (PSNL) Gross Margin (2018 - 2026) Analysis & Trends

Personalis' Gross Margin history runs 9 years deep, the most recent figure standing at 1.82% for Q1 2026.

  • In Q1 2026, Gross Margin fell 3316.0% year-over-year to 1.82%; the TTM figure through Mar 2026 stood at 13.72% (down 1958.0% YoY), while the FY2025 annual figure was 22.65%, down 905.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 1.82%, down from 10.95% in the prior quarter.
  • The five-year high for Gross Margin was 35.59% in Q2 2024, with the low at 1.82% in Q1 2026.
  • The 5-year median for Gross Margin is 26.45% (2023), against an average of 23.22%.
  • The sharpest annual moves came in 2024 and 2026: Gross Margin jumped 1494 bps in 2024, then plunged 3316 bps in 2026.
  • Personalis' Gross Margin stood at 13.83% in 2022, then soared by 91 bps to 26.45% in 2023, then advanced by 2 bps to 27.08% in 2024, then plunged by 60 bps to 10.95% in 2025, then sank by 83 bps to 1.82% in 2026.
  • Business Quant data shows PSNL's Gross Margin at 1.82% in Q1 2026, 10.95% in Q4 2025, and 13.2% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Thermo Fisher Scientific 213.88 Bn 209.81 Bn 8.34 Bn 69.57%
2 Danaher 140.65 Bn 136.30 Bn 3.61 Bn 57.64%
3 Idexx Laboratories 46.02 Bn 45.83 Bn 779.09 Mn 64.04%
4 Agilent Technologies 39.85 Bn 38.05 Bn 990.00 Mn 53.95%
5 Iqvia Holdings 39.20 Bn 37.12 Bn 1.44 Bn 32.85%
6 Natera 38.80 Bn 37.70 Bn 696.04 Mn 99.91%
7 Illumina 30.11 Bn 28.94 Bn 770.00 Mn 66.44%
8 Mettler Toledo International 28.66 Bn 28.61 Bn 650.22 Mn 63.29%
9 Quest Diagnostics 26.24 Bn 25.61 Bn 1.03 Bn 33.75%
10 Personalis 1.40 Bn 1.17 Bn 281,000.00 1.82%

Historic Data

Download Data
DateValue
Mar 31, 2026 1.82%
Dec 31, 2025 10.95%
Sep 30, 2025 13.20%
Jun 30, 2025 27.65%
Mar 31, 2025 34.98%
Dec 31, 2024 27.08%
Sep 30, 2024 34.02%
Jun 30, 2024 35.59%
Mar 31, 2024 28.13%
Dec 31, 2023 26.45%
Sep 30, 2023 19.08%
Jun 30, 2023 28.70%
Mar 31, 2023 25.08%
Dec 31, 2022 13.83%
Sep 30, 2022 16.68%
Jun 30, 2022 23.47%
Mar 31, 2022 28.09%
Dec 31, 2021 38.66%
Sep 30, 2021 36.23%
Jun 30, 2021 37.69%