Personalis (PSNL) Gross Margin (2018 - 2026)
Personalis (PSNL) posted quarterly Gross Margin of 1.82% for Q1 2026, down 3316.0% year-over-year from 0.06% in Q1 2025, and down 83.42% quarter-over-quarter from 10.95% in Q4 2025.
Personalis (PSNL) Gross Margin (2018 - 2026) Analysis & Trends
Personalis' Gross Margin history runs 9 years deep, the most recent figure standing at 1.82% for Q1 2026.
- In Q1 2026, Gross Margin fell 3316.0% year-over-year to 1.82%; the TTM figure through Mar 2026 stood at 13.72% (down 1958.0% YoY), while the FY2025 annual figure was 22.65%, down 905.0% from the prior year.
- Gross Margin for Q1 2026 stood at 1.82%, down from 10.95% in the prior quarter.
- The five-year high for Gross Margin was 35.59% in Q2 2024, with the low at 1.82% in Q1 2026.
- The 5-year median for Gross Margin is 26.45% (2023), against an average of 23.22%.
- The sharpest annual moves came in 2024 and 2026: Gross Margin jumped 1494 bps in 2024, then plunged 3316 bps in 2026.
- Personalis' Gross Margin stood at 13.83% in 2022, then soared by 91 bps to 26.45% in 2023, then advanced by 2 bps to 27.08% in 2024, then plunged by 60 bps to 10.95% in 2025, then sank by 83 bps to 1.82% in 2026.
- Business Quant data shows PSNL's Gross Margin at 1.82% in Q1 2026, 10.95% in Q4 2025, and 13.2% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 213.88 Bn | 209.81 Bn | 8.34 Bn | 69.57% |
| 2 | Danaher | 140.65 Bn | 136.30 Bn | 3.61 Bn | 57.64% |
| 3 | Idexx Laboratories | 46.02 Bn | 45.83 Bn | 779.09 Mn | 64.04% |
| 4 | Agilent Technologies | 39.85 Bn | 38.05 Bn | 990.00 Mn | 53.95% |
| 5 | Iqvia Holdings | 39.20 Bn | 37.12 Bn | 1.44 Bn | 32.85% |
| 6 | Natera | 38.80 Bn | 37.70 Bn | 696.04 Mn | 99.91% |
| 7 | Illumina | 30.11 Bn | 28.94 Bn | 770.00 Mn | 66.44% |
| 8 | Mettler Toledo International | 28.66 Bn | 28.61 Bn | 650.22 Mn | 63.29% |
| 9 | Quest Diagnostics | 26.24 Bn | 25.61 Bn | 1.03 Bn | 33.75% |
| 10 | Personalis | 1.40 Bn | 1.17 Bn | 281,000.00 | 1.82% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.82% |
| Dec 31, 2025 | 10.95% |
| Sep 30, 2025 | 13.20% |
| Jun 30, 2025 | 27.65% |
| Mar 31, 2025 | 34.98% |
| Dec 31, 2024 | 27.08% |
| Sep 30, 2024 | 34.02% |
| Jun 30, 2024 | 35.59% |
| Mar 31, 2024 | 28.13% |
| Dec 31, 2023 | 26.45% |
| Sep 30, 2023 | 19.08% |
| Jun 30, 2023 | 28.70% |
| Mar 31, 2023 | 25.08% |
| Dec 31, 2022 | 13.83% |
| Sep 30, 2022 | 16.68% |
| Jun 30, 2022 | 23.47% |
| Mar 31, 2022 | 28.09% |
| Dec 31, 2021 | 38.66% |
| Sep 30, 2021 | 36.23% |
| Jun 30, 2021 | 37.69% |