Personalis (PSNL) Gross Margin (2018 - 2026)
Personalis' Gross Margin came in at 21.21% for Q2 2026, down 6.43 percentage points from 27.65% a year earlier but up 19.40 percentage points from the prior quarter.
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Analysis
Personalis (PSNL) Gross Margin (2018 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Personalis reported Gross Margin of 12.69%, down 18.76 percentage points year-over-year; for FY2025, it was 22.65%, down 9.05 percentage points from FY2024.
- Gross Margin carries a five-year change of -2.92 percentage points (FY2020 to FY2025).
- Going back by year, Gross Margin was 31.70% in FY2024 (+6.92 pp), 24.78% in FY2023 (+4.26 pp), 20.52% in FY2022 (-16.50 pp) and 37.03% in FY2021 (+11.45 pp).
- The five-year range for quarterly Gross Margin is 1.82% (Q1 2026) to 38.66% (Q4 2021).
- Year-over-year, Gross Margin has declined for five consecutive quarters, with an average year-over-year change of -7.76 percentage points over the last eight quarters.
- The fastest year-over-year change in Gross Margin over five years came in Q3 2024 (a gain of 14.94 percentage points), and the weakest in Q1 2026 (a drop of 33.16 percentage points).
- Business Quant data shows PSNL's Gross Margin at 1.82% (Q1 2026), 10.95% (Q4 2025) and 13.20% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | HCA Healthcare | 102.50 Bn | 98.51 Bn | - | - |
| 2 | Natera | 58.05 Bn | 53.74 Bn | 485.19 Mn | 64.46% |
| 3 | Labcorp Holdings | 26.39 Bn | 24.13 Bn | 1.11 Bn | 29.80% |
| 4 | Quest Diagnostics | 26.28 Bn | 24.41 Bn | 1.03 Bn | 33.75% |
| 5 | Tenet Healthcare | 22.71 Bn | 11.72 Bn | - | - |
| 6 | Guardant Health | 21.59 Bn | 17.65 Bn | 219.03 Mn | 65.39% |
| 7 | BrightSpring Health Services | 12.87 Bn | 11.21 Bn | 492.75 Mn | 12.72% |
| 8 | Fresenius Medical Care AG | 12.49 Bn | 4.44 Bn | 1.52 Bn | 26.95% |
| 9 | Encompass Health | 12.04 Bn | 11.70 Bn | - | - |
| 10 | Personalis | 1.68 Bn | 844.65 Mn | 4.74 Mn | 21.21% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 21.21% |
| Mar 31, 2026 | 1.82% |
| Dec 31, 2025 | 10.95% |
| Sep 30, 2025 | 13.20% |
| Jun 30, 2025 | 27.65% |
| Mar 31, 2025 | 34.98% |
| Dec 31, 2024 | 27.08% |
| Sep 30, 2024 | 34.02% |
| Jun 30, 2024 | 35.59% |
| Mar 31, 2024 | 28.13% |
| Dec 31, 2023 | 26.45% |
| Sep 30, 2023 | 19.08% |
| Jun 30, 2023 | 28.70% |
| Mar 31, 2023 | 25.08% |
| Dec 31, 2022 | 13.83% |
| Sep 30, 2022 | 16.68% |
| Jun 30, 2022 | 23.47% |
| Mar 31, 2022 | 28.09% |
| Dec 31, 2021 | 38.66% |
| Sep 30, 2021 | 36.23% |
API Access
Personalis Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "PSNL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=PSNL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();