Growth Metrics

Personalis (PSNL) Gross Margin (2018 - 2026)

Personalis has reported Gross Margin over the past 8 years, most recently at 10.95% for Q4 2025.

  • For Q4 2025, Gross Margin fell 1613.0% year-over-year to 10.95%; the TTM value through Dec 2025 reached 22.65%, down 905.0%, while the annual FY2025 figure was 22.65%, 905.0% down from the prior year.
  • Gross Margin for Q4 2025 was 10.95% at Personalis, down from 13.2% in the prior quarter.
  • Over five years, Gross Margin peaked at 38.66% in Q4 2021 and troughed at 10.95% in Q4 2025.
  • A 5-year average of 27.06% and a median of 27.87% in 2022 define the central range for Gross Margin.
  • Biggest five-year swings in Gross Margin: plummeted -2484bps in 2022 and later surged 1494bps in 2024.
  • Year by year, Gross Margin stood at 38.66% in 2021, then tumbled by -64bps to 13.83% in 2022, then soared by 91bps to 26.45% in 2023, then increased by 2bps to 27.08% in 2024, then tumbled by -60bps to 10.95% in 2025.
  • Business Quant data shows Gross Margin for PSNL at 10.95% in Q4 2025, 13.2% in Q3 2025, and 27.65% in Q2 2025.