Personalis (PSNL) Gross Margin (2018 - 2026)

Personalis (PSNL) posted quarterly Gross Margin of 1.82% for Q1 2026, down 3316.0% year-over-year from 0.06% in Q1 2025, and down 83.42% on a QoQ basis from 10.95% in Q4 2025.

Personalis (PSNL) Gross Margin (2018 - 2026) Analysis & Trends

Personalis (PSNL) has reported Gross Margin for 9 consecutive years, with 1.82% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Gross Margin fell 3316.0% year-over-year to 1.82%; the TTM figure through Mar 2026 stood at 13.72% (down 1958.0% YoY), while the FY2025 annual figure was 22.65%, down 905.0% from the prior year.
  • Gross Margin came in at 1.82% for Q1 2026 at Personalis, down from 10.95% in the prior quarter.
  • The five-year high for Gross Margin was 35.59% in Q2 2024, with the low at 1.82% in Q1 2026.
  • Average Gross Margin over 5 years is 23.22%, with a median of 26.45% recorded in 2023.
  • Across the five-year window, Gross Margin surged 1494 bps in 2024 and slumped 3316 bps in 2026, its largest moves.
  • Year by year, Gross Margin stood at 13.83% in 2022, then jumped by 91 bps to 26.45% in 2023, then rose by 2 bps to 27.08% in 2024, then slumped by 60 bps to 10.95% in 2025, then tumbled by 83 bps to 1.82% in 2026.
  • According to Business Quant data, Gross Margin over the past three periods registered 1.82%, 10.95%, and 13.2% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Waters 31,055.11 Bn 31,054.65 Bn 1.11 Bn 87.77%
2 Thermo Fisher Scientific 191.02 Bn 187.77 Bn 7.74 Bn 70.37%
3 Danaher 137.16 Bn 131.47 Bn 3.59 Bn 60.34%
4 Idexx Laboratories 42.82 Bn 42.62 Bn 722.74 Mn 63.35%
5 Natera 39.09 Bn 37.99 Bn 696.04 Mn 99.91%
6 Agilent Technologies 37.61 Bn 35.81 Bn 990.00 Mn 53.95%
7 Iqvia Holdings 34.23 Bn 32.25 Bn 1.36 Bn 32.64%
8 Illumina 28.14 Bn 26.98 Bn 721.00 Mn 66.09%
9 Mettler Toledo International 26.40 Bn 26.33 Bn 555.82 Mn 58.68%
10 Personalis 1.44 Bn 1.20 Bn 281,000.00 1.82%

Historic Data

Download Data
DateValue
Mar 31, 2026 1.82%
Dec 31, 2025 10.95%
Sep 30, 2025 13.20%
Jun 30, 2025 27.65%
Mar 31, 2025 34.98%
Dec 31, 2024 27.08%
Sep 30, 2024 34.02%
Jun 30, 2024 35.59%
Mar 31, 2024 28.13%
Dec 31, 2023 26.45%
Sep 30, 2023 19.08%
Jun 30, 2023 28.70%
Mar 31, 2023 25.08%
Dec 31, 2022 13.83%
Sep 30, 2022 16.68%
Jun 30, 2022 23.47%
Mar 31, 2022 28.09%
Dec 31, 2021 38.66%
Sep 30, 2021 36.23%
Jun 30, 2021 37.69%