Personalis (PSNL) Gross Margin (2018 - 2026)
Personalis (PSNL) recorded quarterly Gross Margin of 1.82% in Q1 2026, down 83.42% quarter-over-quarter from 10.95% in Q4 2025, and down 3316.0% on a YoY basis from 0.06% in Q1 2025.
Personalis (PSNL) Gross Margin (2018 - 2026) Analysis & Trends
Personalis' Gross Margin history runs 9 years deep, the most recent figure standing at 1.82% for Q1 2026.
- In Q1 2026, Gross Margin fell 3316.0% year-over-year to 1.82%; the TTM figure through Mar 2026 stood at 13.72% (down 1958.0% YoY), while the FY2025 annual figure was 22.65%, down 905.0% from the prior year.
- Gross Margin was 1.82% for Q1 2026 at Personalis, down from 10.95% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 35.59% in Q2 2024 to a low of 1.82% in Q1 2026.
- Historically, Gross Margin has averaged 23.22% across 5 years, with a median of 26.45% in 2023.
- The sharpest annual moves came in 2024 and 2026: Gross Margin surged 1494 bps in 2024, then sank 3316 bps in 2026.
- A 5-year view of Gross Margin shows it stood at 13.83% in 2022, then jumped by 91 bps to 26.45% in 2023, then climbed by 2 bps to 27.08% in 2024, then sank by 60 bps to 10.95% in 2025, then slumped by 83 bps to 1.82% in 2026.
- The last three Gross Margin figures came in at 1.82% (Q1 2026), 10.95% (Q4 2025), and 13.2% (Q3 2025), per Business Quant data.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 30,529.42 Bn | 30,528.96 Bn | 1.11 Bn | 87.77% |
| 2 | Thermo Fisher Scientific | 183.75 Bn | 180.50 Bn | 7.74 Bn | 70.37% |
| 3 | Danaher | 133.13 Bn | 127.43 Bn | 3.59 Bn | 60.34% |
| 4 | Idexx Laboratories | 46.14 Bn | 45.94 Bn | 722.74 Mn | 63.35% |
| 5 | Agilent Technologies | 38.20 Bn | 36.39 Bn | 990.00 Mn | 53.95% |
| 6 | Natera | 31.50 Bn | 30.40 Bn | 696.04 Mn | 99.91% |
| 7 | Iqvia Holdings | 31.34 Bn | 29.36 Bn | 1.36 Bn | 32.64% |
| 8 | Illumina | 24.51 Bn | 23.36 Bn | 721.00 Mn | 66.09% |
| 9 | Mettler Toledo International | 23.53 Bn | 23.47 Bn | 555.82 Mn | 58.68% |
| 10 | Personalis | 1.01 Bn | 780.57 Mn | 281,000.00 | 1.82% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 1.82% |
| Dec 31, 2025 | 10.95% |
| Sep 30, 2025 | 13.20% |
| Jun 30, 2025 | 27.65% |
| Mar 31, 2025 | 34.98% |
| Dec 31, 2024 | 27.08% |
| Sep 30, 2024 | 34.02% |
| Jun 30, 2024 | 35.59% |
| Mar 31, 2024 | 28.13% |
| Dec 31, 2023 | 26.45% |
| Sep 30, 2023 | 19.08% |
| Jun 30, 2023 | 28.70% |
| Mar 31, 2023 | 25.08% |
| Dec 31, 2022 | 13.83% |
| Sep 30, 2022 | 16.68% |
| Jun 30, 2022 | 23.47% |
| Mar 31, 2022 | 28.09% |
| Dec 31, 2021 | 38.66% |
| Sep 30, 2021 | 36.23% |
| Jun 30, 2021 | 37.69% |