Growth Metrics

Guardant Health (GH) Gross Margin (2017 - 2025)

Guardant Health (GH) has disclosed Gross Margin for 9 consecutive years, with 64.63% as the latest value for Q4 2025.

  • Quarterly Gross Margin rose 1654.0% to 64.63% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 57.11% through Dec 2025, up 333.0% year-over-year, with the annual reading at 64.46% for FY2025, 1384.0% up from the prior year.
  • Gross Margin hit 64.63% in Q4 2025 for Guardant Health, up from 51.97% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 222.36% in Q4 2021 to a low of 31.54% in Q3 2022.
  • Historically, Gross Margin has averaged 63.84% across 5 years, with a median of 50.14% in 2023.
  • Biggest five-year swings in Gross Margin: soared 16231bps in 2021 and later crashed -18653bps in 2022.
  • Year by year, Gross Margin stood at 222.36% in 2021, then tumbled by -84bps to 35.83% in 2022, then soared by 418bps to 185.58% in 2023, then crashed by -74bps to 48.09% in 2024, then surged by 34bps to 64.63% in 2025.
  • Business Quant data shows Gross Margin for GH at 64.63% in Q4 2025, 51.97% in Q3 2025, and 48.47% in Q2 2025.