Growth Metrics

Guardant Health (GH) Gross Margin (2017 - 2026)

Guardant Health's Gross Margin history spans 9 years, with the latest figure at 224.89% for Q4 2025.

  • On a quarterly basis, Gross Margin rose 20057.0% to 224.89% in Q4 2025 year-over-year; TTM through Dec 2025 was 100.0%, a 5143.0% increase, with the full-year FY2025 number at 100.0%, up 4938.0% from a year prior.
  • Gross Margin hit 224.89% in Q4 2025 for Guardant Health, up from 51.97% in the prior quarter.
  • Over the last five years, Gross Margin for GH hit a ceiling of 224.89% in Q4 2025 and a floor of 24.32% in Q4 2024.
  • Historically, Gross Margin has averaged 61.33% across 5 years, with a median of 48.34% in 2023.
  • Biggest five-year swings in Gross Margin: plummeted -16126bps in 2024 and later surged 20057bps in 2025.
  • Tracing GH's Gross Margin over 5 years: stood at 44.87% in 2021, then fell by -20bps to 35.83% in 2022, then surged by 418bps to 185.58% in 2023, then plummeted by -87bps to 24.32% in 2024, then skyrocketed by 825bps to 224.89% in 2025.
  • Business Quant data shows Gross Margin for GH at 224.89% in Q4 2025, 51.97% in Q3 2025, and 48.47% in Q2 2025.