Guardant Health (GH) Gross Margin (2017 - 2026)
Guardant Health (GH) posted Gross Margin of 65.22% for Q1 2026, down 35.3% sequentially from 100.81% in Q4 2025, and up 194.0% YoY from 22.18% in Q1 2025.
Guardant Health (GH) Gross Margin (2017 - 2026) Analysis & Trends
Guardant Health (GH) has 10 years of Gross Margin data on file, last reported at 65.22% in Q1 2026.
- Quarterly Gross Margin rose 194.0% year-over-year to 65.22% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 71.19% (up 365.0% YoY) and the FY2025 annual result came in at 64.46%, up 367.0% from the prior year.
- Gross Margin declined to 65.22% in Q1 2026 per GH's latest filing, from 100.81% in the prior quarter.
- The five-year high for Gross Margin was 185.58% in Q4 2023, with the low at 31.54% in Q3 2022.
- Average Gross Margin over 5 years is 63.08%, with a median of 59.14% recorded in 2024.
- Year-over-year, Gross Margin jumped 14975 bps in 2023 and plunged 10026 bps in 2024.
- Guardant Health's Gross Margin stood at 35.83% in 2022, then jumped by 418 bps to 185.58% in 2023, then slumped by 54 bps to 85.32% in 2024, then increased by 18 bps to 100.81% in 2025, then sank by 35 bps to 65.22% in 2026.
- Business Quant data shows GH's Gross Margin at 65.22% in Q1 2026, 100.81% in Q4 2025, and 51.97% in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | 87.77% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 70.37% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 60.34% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 63.35% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | 99.91% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 53.95% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 32.64% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 66.09% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 58.68% |
| 10 | Guardant Health | 22.42 Bn | 21.31 Bn | 196.75 Mn | 65.22% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 65.22% |
| Dec 31, 2025 | 100.81% |
| Sep 30, 2025 | 51.97% |
| Jun 30, 2025 | 65.01% |
| Mar 31, 2025 | 63.28% |
| Dec 31, 2024 | 85.32% |
| Sep 30, 2024 | 61.10% |
| Jun 30, 2024 | 59.14% |
| Mar 31, 2024 | 61.25% |
| Dec 31, 2023 | 185.58% |
| Sep 30, 2023 | 51.80% |
| Jun 30, 2023 | 48.20% |
| Mar 31, 2023 | 40.86% |
| Dec 31, 2022 | 35.83% |
| Sep 30, 2022 | 31.54% |
| Jun 30, 2022 | 32.56% |
| Mar 31, 2022 | 32.95% |
| Dec 31, 2021 | 44.87% |
| Sep 30, 2021 | 47.01% |
| Jun 30, 2021 | 48.19% |