Guardant Health (GH) Gross Margin (2017 - 2026)

Guardant Health's (GH) quarterly Gross Margin came in at 65.22% in Q1 2026, up 194.0% year-on-year from 22.18% in Q1 2025, and down 35.3% quarter-over-quarter from 100.81% in Q4 2025.

Guardant Health (GH) Gross Margin (2017 - 2026) Analysis & Trends

Guardant Health has disclosed Gross Margin across 10 years of filings, most recently posting 65.22% for Q1 2026.

  • Gross Margin for Q1 2026 came in at 65.22%, up 194.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 71.19% (up 365.0% YoY), and the FY2025 annual result was 64.46%, up 367.0% from the prior year.
  • Gross Margin came in at 65.22% for Q1 2026 at Guardant Health, down from 100.81% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 185.58% in Q4 2023 to a low of 31.54% in Q3 2022.
  • The 5-year median for Gross Margin is 59.14% (2024), against an average of 63.08%.
  • Across the five-year window, Gross Margin soared 14975 bps in 2023 and slumped 10026 bps in 2024, its largest moves.
  • Guardant Health's Gross Margin stood at 35.83% in 2022, then jumped by 418 bps to 185.58% in 2023, then sank by 54 bps to 85.32% in 2024, then advanced by 18 bps to 100.81% in 2025, then plunged by 35 bps to 65.22% in 2026.
  • The last three Gross Margin figures came in at 65.22% (Q1 2026), 100.81% (Q4 2025), and 51.97% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Waters 29,902.70 Bn 29,902.24 Bn 1.11 Bn 87.77%
2 Thermo Fisher Scientific 175.99 Bn 172.74 Bn 7.74 Bn 70.37%
3 Danaher 129.87 Bn 124.18 Bn 3.59 Bn 60.34%
4 Idexx Laboratories 44.75 Bn 44.55 Bn 722.74 Mn 63.35%
5 Agilent Technologies 37.52 Bn 35.72 Bn 990.00 Mn 53.95%
6 Iqvia Holdings 30.91 Bn 28.94 Bn 1.36 Bn 32.64%
7 Natera 30.21 Bn 29.11 Bn 696.04 Mn 99.91%
8 Illumina 24.19 Bn 23.04 Bn 721.00 Mn 66.09%
9 Mettler Toledo International 23.12 Bn 23.06 Bn 555.82 Mn 58.68%
10 Guardant Health 16.38 Bn 15.28 Bn 196.75 Mn 65.22%

Historic Data

Download Data
DateValue
Mar 31, 2026 65.22%
Dec 31, 2025 100.81%
Sep 30, 2025 51.97%
Jun 30, 2025 65.01%
Mar 31, 2025 63.28%
Dec 31, 2024 85.32%
Sep 30, 2024 61.10%
Jun 30, 2024 59.14%
Mar 31, 2024 61.25%
Dec 31, 2023 185.58%
Sep 30, 2023 51.80%
Jun 30, 2023 48.20%
Mar 31, 2023 40.86%
Dec 31, 2022 35.83%
Sep 30, 2022 31.54%
Jun 30, 2022 32.56%
Mar 31, 2022 32.95%
Dec 31, 2021 44.87%
Sep 30, 2021 47.01%
Jun 30, 2021 48.19%