Guardant Health (GH) Gross Margin (2017 - 2026)
Guardant Health's (GH) quarterly Gross Margin came in at 65.22% in Q1 2026, up 194.0% year-on-year from 22.18% in Q1 2025, and down 35.3% quarter-over-quarter from 100.81% in Q4 2025.
Guardant Health (GH) Gross Margin (2017 - 2026) Analysis & Trends
Guardant Health has disclosed Gross Margin across 10 years of filings, most recently posting 65.22% for Q1 2026.
- Gross Margin for Q1 2026 came in at 65.22%, up 194.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 71.19% (up 365.0% YoY), and the FY2025 annual result was 64.46%, up 367.0% from the prior year.
- Gross Margin came in at 65.22% for Q1 2026 at Guardant Health, down from 100.81% in the prior quarter.
- In the past five years, Gross Margin ranged from a high of 185.58% in Q4 2023 to a low of 31.54% in Q3 2022.
- The 5-year median for Gross Margin is 59.14% (2024), against an average of 63.08%.
- Across the five-year window, Gross Margin soared 14975 bps in 2023 and slumped 10026 bps in 2024, its largest moves.
- Guardant Health's Gross Margin stood at 35.83% in 2022, then jumped by 418 bps to 185.58% in 2023, then sank by 54 bps to 85.32% in 2024, then advanced by 18 bps to 100.81% in 2025, then plunged by 35 bps to 65.22% in 2026.
- The last three Gross Margin figures came in at 65.22% (Q1 2026), 100.81% (Q4 2025), and 51.97% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 29,902.70 Bn | 29,902.24 Bn | 1.11 Bn | 87.77% |
| 2 | Thermo Fisher Scientific | 175.99 Bn | 172.74 Bn | 7.74 Bn | 70.37% |
| 3 | Danaher | 129.87 Bn | 124.18 Bn | 3.59 Bn | 60.34% |
| 4 | Idexx Laboratories | 44.75 Bn | 44.55 Bn | 722.74 Mn | 63.35% |
| 5 | Agilent Technologies | 37.52 Bn | 35.72 Bn | 990.00 Mn | 53.95% |
| 6 | Iqvia Holdings | 30.91 Bn | 28.94 Bn | 1.36 Bn | 32.64% |
| 7 | Natera | 30.21 Bn | 29.11 Bn | 696.04 Mn | 99.91% |
| 8 | Illumina | 24.19 Bn | 23.04 Bn | 721.00 Mn | 66.09% |
| 9 | Mettler Toledo International | 23.12 Bn | 23.06 Bn | 555.82 Mn | 58.68% |
| 10 | Guardant Health | 16.38 Bn | 15.28 Bn | 196.75 Mn | 65.22% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 65.22% |
| Dec 31, 2025 | 100.81% |
| Sep 30, 2025 | 51.97% |
| Jun 30, 2025 | 65.01% |
| Mar 31, 2025 | 63.28% |
| Dec 31, 2024 | 85.32% |
| Sep 30, 2024 | 61.10% |
| Jun 30, 2024 | 59.14% |
| Mar 31, 2024 | 61.25% |
| Dec 31, 2023 | 185.58% |
| Sep 30, 2023 | 51.80% |
| Jun 30, 2023 | 48.20% |
| Mar 31, 2023 | 40.86% |
| Dec 31, 2022 | 35.83% |
| Sep 30, 2022 | 31.54% |
| Jun 30, 2022 | 32.56% |
| Mar 31, 2022 | 32.95% |
| Dec 31, 2021 | 44.87% |
| Sep 30, 2021 | 47.01% |
| Jun 30, 2021 | 48.19% |