ProQR Therapeutics (PRQR) Return on Invested Capital [ROIC] (2017 - 2026)
ProQR Therapeutics (PRQR) posted Return on Invested Capital [ROIC] of -67.57% for the quarter ended Jun 30, 2026, down 13.93 percentage points from -53.64% a year earlier.
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Analysis
ProQR Therapeutics (PRQR) Return on Invested Capital [ROIC] (2017 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, ProQR Therapeutics' Return on Invested Capital [ROIC] came in at -60.56%, down 16.96 percentage points from the prior year.
- Annual Return on Invested Capital [ROIC] shows a five-year change of -13.15 percentage points (years ended Dec 2020 to Dec 2025).
- In prior years, ProQR Therapeutics' Return on Invested Capital [ROIC] was -43.60% in the year ended Dec 31, 2024 (+11.74 pp), -55.34% in the year ended Dec 31, 2023 (-1.76 pp), -53.58% in the year ended Dec 31, 2022 (-2.66 pp) and -50.92% in the year ended Dec 31, 2021 (-3.51 pp).
- Quarterly Return on Invested Capital [ROIC] has run from a low of -93.07% in the quarter ended Dec 31, 2022 to a high of -36.39% in the quarter ended Sep 30, 2021 over five years.
- On a year-over-year basis, Return on Invested Capital [ROIC] increased in three of the last six quarters, with an average year-over-year change of -0.55 percentage points.
- The strongest year-over-year quarter for Return on Invested Capital [ROIC] in the past five years was the quarter ended Dec 31, 2023, with a gain of 27.61 percentage points; the weakest was the quarter ended Dec 31, 2022, with a drop of 54.49 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 30.89% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 17.57% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 24.28% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 2.52% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 23.11% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 15.60% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -6.11% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 12.34% |
| 10 | ProQR Therapeutics | 138.02 Mn | -322.63 Mn | - | -68.86% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -68.86% |
| Dec 31, 2025 | -71.93% |
| Sep 30, 2025 | -62.81% |
| Jun 30, 2025 | -51.99% |
| Dec 31, 2024 | -50.46% |
| Sep 30, 2024 | -78.87% |
| Jun 30, 2024 | -66.01% |
| Mar 31, 2024 | -71.21% |
| Dec 31, 2023 | -65.43% |
| Sep 30, 2023 | -68.78% |
| Jun 30, 2023 | -78.10% |
| Dec 31, 2022 | -90.60% |
| Sep 30, 2022 | -70.95% |
| Jun 30, 2022 | -48.11% |
| Mar 31, 2022 | -42.07% |
| Dec 31, 2021 | -38.56% |
| Sep 30, 2021 | -37.00% |
| Jun 30, 2021 | -51.63% |
| Mar 31, 2021 | -59.83% |
| Dec 31, 2020 | -50.67% |
API Access
ProQR Therapeutics Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();