ProQR Therapeutics (PRQR) Return on Invested Capital [ROIC] (2017 - 2026)
ProQR Therapeutics (PRQR) posted Return on Invested Capital [ROIC] of -67.57% for the quarter ended Jun 30, 2026, down 13.93 percentage points from -53.64% a year earlier.
Powered by 
Analysis
ProQR Therapeutics (PRQR) Return on Invested Capital [ROIC] (2017 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, ProQR Therapeutics' Return on Invested Capital [ROIC] came in at -60.56%, down 16.96 percentage points from the prior year.
- Annual Return on Invested Capital [ROIC] shows a five-year change of -13.15 percentage points (years ended Dec 2020 to Dec 2025).
- In prior years, ProQR Therapeutics' Return on Invested Capital [ROIC] was -43.60% in the year ended Dec 31, 2024 (+11.74 pp), -55.34% in the year ended Dec 31, 2023 (-1.76 pp), -53.58% in the year ended Dec 31, 2022 (-2.66 pp) and -50.92% in the year ended Dec 31, 2021 (-3.51 pp).
- Quarterly Return on Invested Capital [ROIC] has run from a low of -93.07% in the quarter ended Dec 31, 2022 to a high of -36.39% in the quarter ended Sep 30, 2021 over five years.
- On a year-over-year basis, Return on Invested Capital [ROIC] increased in three of the last six quarters, with an average year-over-year change of -0.55 percentage points.
- The strongest year-over-year quarter for Return on Invested Capital [ROIC] in the past five years was the quarter ended Dec 31, 2023, with a gain of 27.61 percentage points; the weakest was the quarter ended Dec 31, 2022, with a drop of 54.49 percentage points.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 37.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 16.10% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 18.68% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | 3.56% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 21.95% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 28.83% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 14.33% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -5.97% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 13.44% |
| 10 | ProQR Therapeutics | 171.74 Mn | -291.86 Mn | - | -67.57% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -67.57% |
| Dec 31, 2025 | -71.77% |
| Sep 30, 2025 | -63.51% |
| Jun 30, 2025 | -53.64% |
| Dec 31, 2024 | -49.68% |
| Sep 30, 2024 | -79.85% |
| Jun 30, 2024 | -66.33% |
| Mar 31, 2024 | -72.30% |
| Dec 31, 2023 | -65.46% |
| Sep 30, 2023 | -67.78% |
| Jun 30, 2023 | -78.69% |
| Dec 31, 2022 | -93.07% |
| Sep 30, 2022 | -69.24% |
| Jun 30, 2022 | -47.43% |
| Mar 31, 2022 | -42.33% |
| Dec 31, 2021 | -38.57% |
| Sep 30, 2021 | -36.39% |
| Jun 30, 2021 | -50.63% |
| Mar 31, 2021 | -60.07% |
| Dec 31, 2020 | -51.35% |
API Access
ProQR Therapeutics Return on Invested Capital [ROIC] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-invested-capital-[roic]", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-invested-capital-%5Broic%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();