ProQR Therapeutics (PRQR) Return on Invested Capital (2018 - 2025)

ProQR Therapeutics (PRQR) has reported Return on Invested Capital for 8 consecutive years, with 0.02% the latest figure, recorded in Q4 2025.

• Quarterly Return on Invested Capital fell 1.0% year-over-year to 0.02% in Q4 2025, while the trailing twelve-month figure through Dec 2025 was 0.02% (down 1.0% YoY) and the FY2025 annual result came in at 0.04%, down 2.0% from the prior year.
• Return on Invested Capital steadied at 0.02% in Q4 2025 per PRQR's latest filing, from 0.02% in the prior quarter.
• Over the last five years, Return on Invested Capital for PRQR reached as high as 0.01% in Q2 2022 and fell as low as 0.03% in Q3 2021.
• A 5-year average of 0.01% and a median of 0.01% in 2023 frame the typical range for Return on Invested Capital.
• Annual changes were most pronounced in 2021 — Return on Invested Capital climbed 30 bps — and 2023, when it dropped 1 bps.
• Year by year, Return on Invested Capital stood at 0.02% in 2021, then jumped by 56 bps to 0.01% in 2022, then sank by 72 bps to 0.01% in 2023, then climbed by 20 bps to 0.01% in 2024, then slumped by 49 bps to 0.02% in 2025.
• According to Business Quant data, Return on Invested Capital over the past three periods registered 0.02%, 0.02%, and 0.02% for Q4 2025, Q3 2025, and Q2 2025 respectively.