ProQR Therapeutics (PRQR) Return on Equity [ROE] (2014 - 2026)
ProQR Therapeutics' Return on Equity [ROE] came in at -71.94% for the quarter ended Jun 30, 2026, down 17.51 percentage points from -54.44% a year earlier but up 31.92 percentage points from the prior quarter.
Powered by 
Analysis
ProQR Therapeutics (PRQR) Return on Equity [ROE] (2014 - 2026) Analysis & Trends
For the year ended Dec 31, 2025, ProQR Therapeutics' Return on Equity [ROE] was -62.86%, down 20.12 percentage points from the prior year.
- Return on Equity [ROE] carries a five-year change of -0.12 percentage points (years ended Dec 2020 to Dec 2025).
- Going back by year, Return on Equity [ROE] was -42.74% in the year ended Dec 31, 2024 (+9.42 pp), -52.15% in the year ended Dec 31, 2023 (+13.76 pp), -65.92% in the year ended Dec 31, 2022 (+6.18 pp) and -72.09% in the year ended Dec 31, 2021 (-9.35 pp).
- The five-year range for quarterly Return on Equity [ROE] is -103.86% (the quarter ended Mar 31, 2026) to -36.42% (the quarter ended Mar 31, 2025).
- Year-over-year, Return on Equity [ROE] has declined for three consecutive quarters, with an average year-over-year change of -6.51 percentage points over the last eight quarters.
- The fastest year-over-year change in Return on Equity [ROE] over five years came in the quarter ended Dec 31, 2023 (a gain of 35.92 percentage points), and the weakest in the quarter ended Mar 31, 2026 (a drop of 67.44 percentage points).
- Business Quant data shows PRQR's Return on Equity [ROE] at -103.86% (quarter ended Mar 31, 2026), -76.72% (quarter ended Dec 31, 2025) and -66.22% (quarter ended Sep 30, 2025) in the three quarters before the quarter ended Jun 30, 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | ProQR Therapeutics | 174.90 Mn | -288.70 Mn | - | -71.94% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -71.94% |
| Mar 31, 2026 | -103.86% |
| Dec 31, 2025 | -76.72% |
| Sep 30, 2025 | -66.22% |
| Jun 30, 2025 | -54.44% |
| Mar 31, 2025 | -36.42% |
| Dec 31, 2024 | -49.26% |
| Sep 30, 2024 | -82.85% |
| Jun 30, 2024 | -62.88% |
| Mar 31, 2024 | -69.95% |
| Dec 31, 2023 | -63.15% |
| Sep 30, 2023 | -70.71% |
| Jun 30, 2023 | -92.80% |
| Mar 31, 2023 | -93.04% |
| Dec 31, 2022 | -99.07% |
| Sep 30, 2022 | -91.45% |
| Jun 30, 2022 | -66.19% |
| Mar 31, 2022 | -60.42% |
| Dec 31, 2021 | -51.74% |
| Sep 30, 2021 | -46.31% |
API Access
ProQR Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "PRQR", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PRQR&period=max&api_key=YOUR_API_KEY");
const data = await res.json();