Prelude Therapeutics (PRLD) Return on Equity [ROE] (2020 - 2026)
Prelude Therapeutics (PRLD) recorded Return on Equity [ROE] of -69.51% in Q2 2026, up 81.32 percentage points from -150.83% a year earlier and up 61.12 percentage points from the prior quarter.
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Analysis
Prelude Therapeutics (PRLD) Return on Equity [ROE] (2020 - 2026) Analysis & Trends
For FY2025, Prelude Therapeutics reported Return on Equity [ROE] of -104.52%, down 28.70 percentage points from FY2024.
- Annual Return on Equity [ROE] has declined for four straight years, with a five-year change of -32.31 percentage points (FY2020 to FY2025).
- Across earlier years, Return on Equity [ROE] came in at -75.82% in FY2024 (-14.65 pp), -61.16% in FY2023 (-9.83 pp), -51.33% in FY2022 (-5.66 pp) and -45.67% in FY2021 (+26.53 pp).
- The Q2 2026 figure is the highest quarterly Return on Equity [ROE] since Q1 2024.
- On a year-over-year basis, Return on Equity [ROE] rose in 1 of the last eight quarters, with an average year-over-year change of -38.00 percentage points.
- Peak year-over-year performance for Return on Equity [ROE] in the last five years was a gain of 81.32 percentage points in Q2 2026, against a drop of 95.58 percentage points in Q3 2025 at the low end.
- Per Business Quant, the preceding three quarters came in at -130.63% (Q1 2026), -164.45% (Q4 2025) and -180.17% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Prelude Therapeutics | 312.03 Mn | -285.27 Mn | - | -69.51% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -69.51% |
| Mar 31, 2026 | -130.63% |
| Dec 31, 2025 | -164.45% |
| Sep 30, 2025 | -180.17% |
| Jun 30, 2025 | -150.83% |
| Mar 31, 2025 | -119.31% |
| Dec 31, 2024 | -97.06% |
| Sep 30, 2024 | -84.59% |
| Jun 30, 2024 | -72.40% |
| Mar 31, 2024 | -61.41% |
| Dec 31, 2023 | -55.65% |
| Sep 30, 2023 | -51.28% |
| Jun 30, 2023 | -57.30% |
| Mar 31, 2023 | -66.01% |
| Dec 31, 2022 | -59.85% |
| Sep 30, 2022 | -53.75% |
| Jun 30, 2022 | -49.18% |
| Mar 31, 2022 | -44.57% |
| Dec 31, 2021 | -38.09% |
| Sep 30, 2021 | -31.03% |
API Access
Prelude Therapeutics Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PRLD&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "PRLD", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PRLD&period=max&api_key=YOUR_API_KEY");
const data = await res.json();