Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026)
Prelude Therapeutics' (PRLD) quarterly Return on Capital Employed came in at 94.79% in Q1 2026, up 620.0% year-on-year from 13.17% in Q1 2025, and up 41.04% quarter-over-quarter from 160.77% in Q4 2025.
Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026) Analysis & Trends
Prelude Therapeutics has disclosed Return on Capital Employed across 7 years of filings, most recently posting 94.79% for Q1 2026.
- Return on Capital Employed for Q1 2026 came in at 94.79%, up 620.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 94.79% (up 620.0% YoY), and the FY2025 annual result was 99.19%, down 2966.0% from the prior year.
- Return on Capital Employed came in at 94.79% for Q1 2026 at Prelude Therapeutics, up from 160.77% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 44.09% in Q1 2022 to a low of 160.77% in Q4 2025.
- The 5-year median for Return on Capital Employed is 64.49% (2023), against an average of 78.74%.
- Across the five-year window, Return on Capital Employed soared 831 bps in 2024 and plunged 7384 bps in 2025, its largest moves.
- Prelude Therapeutics' Return on Capital Employed stood at 58.91% in 2022, then increased by 9 bps to 53.71% in 2023, then sank by 62 bps to 86.93% in 2024, then tumbled by 85 bps to 160.77% in 2025, then soared by 41 bps to 94.79% in 2026.
- The last three Return on Capital Employed figures came in at 94.79% (Q1 2026), 160.77% (Q4 2025), and 139.7% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | - |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | - |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | 450.31% |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | 51.73% |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | -107.40% |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | - |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 21.10% |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -50.43% |
| 10 | Prelude Therapeutics | 314.40 Mn | 169.80 Mn | - | -94.79% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -94.79% |
| Dec 31, 2025 | -160.77% |
| Sep 30, 2025 | -139.70% |
| Jun 30, 2025 | -125.96% |
| Mar 31, 2025 | -100.99% |
| Dec 31, 2024 | -86.93% |
| Sep 30, 2024 | -75.99% |
| Jun 30, 2024 | -66.99% |
| Mar 31, 2024 | -56.18% |
| Dec 31, 2023 | -53.71% |
| Sep 30, 2023 | -50.77% |
| Jun 30, 2023 | -55.87% |
| Mar 31, 2023 | -64.49% |
| Dec 31, 2022 | -58.91% |
| Sep 30, 2022 | -53.75% |
| Jun 30, 2022 | -48.65% |
| Mar 31, 2022 | -44.09% |
| Dec 31, 2021 | -38.04% |
| Sep 30, 2021 | -31.23% |
| Jun 30, 2021 | -25.35% |