Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026)
Prelude Therapeutics (PRLD) reported Return on Capital Employed of 94.79% for Q1 2026, up 620.0% on a YoY basis from 13.17% in Q1 2025, and up 41.04% sequentially from 160.77% in Q4 2025.
Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026) Analysis & Trends
Prelude Therapeutics (PRLD) has 7 years of Return on Capital Employed data on file, last reported at 94.79% in Q1 2026.
- For the quarter ending Q1 2026, Return on Capital Employed rose 620.0% year-over-year to 94.79%; the trailing twelve-month figure through Mar 2026 stood at 94.79% (up 620.0% YoY), and the FY2025 full-year result was 99.19%, down 2966.0% from the prior year.
- Return on Capital Employed improved to 94.79% in Q1 2026, from 160.77% in the prior quarter.
- In the past five years, Return on Capital Employed ranged from a high of 44.09% in Q1 2022 to a low of 160.77% in Q4 2025.
- A 5-year average of 78.74% and a median of 64.49% in 2023 frame the typical range for Return on Capital Employed.
- Across the five-year window, Return on Capital Employed soared 831 bps in 2024 and slumped 7384 bps in 2025, its largest moves.
- Tracing PRLD's Return on Capital Employed over 5 years: stood at 58.91% in 2022, then grew by 9 bps to 53.71% in 2023, then slumped by 62 bps to 86.93% in 2024, then plunged by 85 bps to 160.77% in 2025, then surged by 41 bps to 94.79% in 2026.
- Business Quant data shows PRLD's Return on Capital Employed at 94.79% in Q1 2026, 160.77% in Q4 2025, and 139.7% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROCE (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -31.80% |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 10.46% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -68.47% |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 21.10% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 10.19% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -68.84% |
| 10 | Prelude Therapeutics | 324.30 Mn | 179.71 Mn | - | -94.79% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -94.79% |
| Dec 31, 2025 | -160.77% |
| Sep 30, 2025 | -139.70% |
| Jun 30, 2025 | -125.96% |
| Mar 31, 2025 | -100.99% |
| Dec 31, 2024 | -86.93% |
| Sep 30, 2024 | -75.99% |
| Jun 30, 2024 | -66.99% |
| Mar 31, 2024 | -56.18% |
| Dec 31, 2023 | -53.71% |
| Sep 30, 2023 | -50.77% |
| Jun 30, 2023 | -55.87% |
| Mar 31, 2023 | -64.49% |
| Dec 31, 2022 | -58.91% |
| Sep 30, 2022 | -53.75% |
| Jun 30, 2022 | -48.65% |
| Mar 31, 2022 | -44.09% |
| Dec 31, 2021 | -38.04% |
| Sep 30, 2021 | -31.23% |
| Jun 30, 2021 | -25.35% |