Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026)

Prelude Therapeutics (PRLD) reported Return on Capital Employed of 94.79% for Q1 2026, up 620.0% on a YoY basis from 13.17% in Q1 2025, and up 41.04% sequentially from 160.77% in Q4 2025.

Prelude Therapeutics (PRLD) Return on Capital Employed (2020 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 7 years of Return on Capital Employed data on file, last reported at 94.79% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Capital Employed rose 620.0% year-over-year to 94.79%; the trailing twelve-month figure through Mar 2026 stood at 94.79% (up 620.0% YoY), and the FY2025 full-year result was 99.19%, down 2966.0% from the prior year.
  • Return on Capital Employed improved to 94.79% in Q1 2026, from 160.77% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 44.09% in Q1 2022 to a low of 160.77% in Q4 2025.
  • A 5-year average of 78.74% and a median of 64.49% in 2023 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed soared 831 bps in 2024 and slumped 7384 bps in 2025, its largest moves.
  • Tracing PRLD's Return on Capital Employed over 5 years: stood at 58.91% in 2022, then grew by 9 bps to 53.71% in 2023, then slumped by 62 bps to 86.93% in 2024, then plunged by 85 bps to 160.77% in 2025, then surged by 41 bps to 94.79% in 2026.
  • Business Quant data shows PRLD's Return on Capital Employed at 94.79% in Q1 2026, 160.77% in Q4 2025, and 139.7% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -31.80%
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 10.46%
4 NuCana 279.75 Bn 279.75 Bn - -68.47%
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 21.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 10.19%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -68.84%
10 Prelude Therapeutics 324.30 Mn 179.71 Mn - -94.79%

Historic Data

Download Data
DateValue
Mar 31, 2026 -94.79%
Dec 31, 2025 -160.77%
Sep 30, 2025 -139.70%
Jun 30, 2025 -125.96%
Mar 31, 2025 -100.99%
Dec 31, 2024 -86.93%
Sep 30, 2024 -75.99%
Jun 30, 2024 -66.99%
Mar 31, 2024 -56.18%
Dec 31, 2023 -53.71%
Sep 30, 2023 -50.77%
Jun 30, 2023 -55.87%
Mar 31, 2023 -64.49%
Dec 31, 2022 -58.91%
Sep 30, 2022 -53.75%
Jun 30, 2022 -48.65%
Mar 31, 2022 -44.09%
Dec 31, 2021 -38.04%
Sep 30, 2021 -31.23%
Jun 30, 2021 -25.35%