Prelude Therapeutics PRLD Institutional Ownership

NASDAQ PRLD

$3.95 -0.01 (-0.25%)

As of: Sep 30, 2026 · 2:31 PM EDT

Institutions by Trading Activity

77 Institutions

Increased 61 79.2%

Unchanged 8 10.4%

Reduced 8 10.4%

Ownership Statistics

13F · as of 30 Jun, 2026

Institutional Ownership

50.48%

▲+13.19 pp QoQ

Shares Held by Institutions

49.67Mn

of 98.39Mn outstanding

▲+70.70% QoQ

Shares Outstanding

98.39Mn

48.72Mn held outside 13F filers

Institutional Investors

filed 13F for Jun 2026

▲+22 vs prior quarter

Net Shares Added (QoQ)

+20.57Mn

accumulated since last quarter

Value of Holdings

$196.68Mn

reported market value

Shares Owned by Institutions

Shares held % of outstanding

Latest —

Average ownership —

Peak ownership —

Shares Purchased/Sold by Institutions

Accumulated Distributed

Latest quarter —

Net over range —

Accumulating quarters —

Ownership Summary

Quarter ending 30 Jun, 2026

Prelude Therapeutics Inc (NASDAQ:PRLD) showed up in the 13F filings of 77 institutional investors as of June 2026.

Collectively, these holders controlled 50.5% of Prelude Therapeutics's outstanding shares in June 2026, up from 37.3% in March 2026.
They increased total shares held in Prelude Therapeutics by 70.7% from the prior quarter, while the number of investors in PRLD increased 60.42% year over year.
During the quarter, 61 of these 77 funds increased positions in PRLD, 8 reduced exposure, and 8 held steady.
Institutional investors collectively held 49.67Mn shares in Prelude Therapeutics as of June 2026, up by 20.57Mn shares quarter on quarter, and up 22.8Mn shares year over year.
As of June 30, 2026, ORBIMED ADVISORS LLC held the largest stake in Prelude Therapeutics with 13.72Mn shares, accounting for 13.95% of total shares outstanding.
The largest buyers of Prelude Therapeutics for the quarter ending June 2026 were RA CAPITAL MANAGEMENT, L.P. (6.48Mn), Soleus Capital Management, L.P. (3.38Mn), ORBIMED ADVISORS LLC (2.82Mn), BlackRock, Inc. (1.48Mn), Kynam Capital Management, LP (822.54K).
Leading sellers of Prelude Therapeutics shares for the quarter ending June 2026 were MARSHALL WACE, LLP (168.21K), Goldman Sachs Group Inc (115.64K), CITADEL ADVISORS LLC (101.82K), Bank Of America Corp /De/ (32.65K), Qube Research & Technologies Ltd (3.31K).
Prelude Therapeutics's 10 largest shareholders as of June 2026 include ORBIMED ADVISORS LLC (13.72Mn), BAKER BROS. ADVISORS LP (10.12Mn), RA CAPITAL MANAGEMENT, L.P. (6.48Mn), Soleus Capital Management, L.P. (3.38Mn), Kynam Capital Management, LP (2.42Mn), VANGUARD CAPITAL MANAGEMENT LLC (2.01Mn), BlackRock, Inc. (1.8Mn), SPHERA FUNDS MANAGEMENT LTD. (1.02Mn), TWO SIGMA INVESTMENTS, LP (993.37K), ADAR1 Capital Management, LLC (900.9K) per Business Quant data.

Form 13F Holdings

77 Institutional Holders

Report period 30 Jun, 2026

Total shares held 49.67Mn

Of outstanding 50.48%

#	Institution	CIK	Shares Held	% of Outstanding	Change (QoQ)	Change (%)	Value (USD)
1	ORBIMED ADVISORS LLC	0001055951	13,724,571	13.95%	▲2,815,315	+25.81%	$73.15Mn
2	BAKER BROS. ADVISORS LP	0001263508	10,123,824	10.29%	0	0.00%	$53.96Mn
3	RA CAPITAL MANAGEMENT, L.P.	0001346824	6,475,882	6.58%	▲6,475,882	0.00%	$34.52Mn
4	Soleus Capital Management, L.P.	0001802630	3,378,378	3.43%	▲3,378,378	0.00%	$18.01Mn
5	Kynam Capital Management, LP	0001907884	2,415,087	2.45%	▲822,536	+51.65%	$12.87Mn
6	VANGUARD CAPITAL MANAGEMENT LLC	0002100119	2,009,445	2.04%	▲779,039	+63.32%	$10.71Mn
7	BlackRock, Inc.	0002012383	1,797,501	1.83%	▲1,475,615	+458.43%	$9.58Mn
8	SPHERA FUNDS MANAGEMENT LTD.	0001496201	1,019,832	1.04%	▲461,493	+82.65%	$5.44Mn
9	TWO SIGMA INVESTMENTS, LP	0001179392	993,369	1.01%	▲69,743	+7.55%	$5.29Mn
10	ADAR1 Capital Management, LLC	0001940272	900,900	0.92%	▲748,075	+489.50%	$4.80Mn
11	MILLENNIUM MANAGEMENT LLC	0001273087	844,993	0.86%	▲462,256	+120.78%	$4.50Mn
12	GEODE CAPITAL MANAGEMENT, LLC	0001214717	841,862	0.86%	▲539,404	+178.34%	$4.49Mn
13	ADAGE CAPITAL PARTNERS GP, L.L.C.	0001165408	766,095	0.78%	▲766,095	0.00%	$4.08Mn
14	ACADIAN ASSET MANAGEMENT LLC	0000916542	611,359	0.62%	▲99,840	+19.52%	$3.25K
15	Morgan Stanley	0000895421	503,860	0.51%	▲181,699	+56.40%	$2.69Mn
16	State Street Corp	0000093751	428,787	0.44%	▲290,556	+210.20%	$2.29Mn
17	UBS Group AG	0001610520	318,797	0.32%	▲254,292	+394.22%	$1.70Mn
18	VANGUARD FIDUCIARY TRUST CO	0000933478	284,886	0.29%	▲127,506	+81.02%	$1.52Mn
19	RENAISSANCE TECHNOLOGIES LLC	0001037389	281,200	0.29%	▲6,000	+2.18%	$1.50Mn
20	Northern Trust Corp	0000073124	240,599	0.24%	▲190,479	+380.05%	$1.28Mn

Showing 1 to 20 of 77 holders