Prelude Therapeutics (PRLD) Operating Income (2019 - 2026)
Prelude Therapeutics (PRLD) reported Operating Income of -$14.2 million for Q1 2026, up 59.03% on a YoY basis from -$8.9 million in Q1 2025, and up 18.28% sequentially from -$17.3 million in Q4 2025.
Prelude Therapeutics (PRLD) Operating Income (2019 - 2026) Analysis & Trends
Prelude Therapeutics (PRLD) has 8 years of Operating Income data on file, last reported at -$14.2 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Income rose 59.03% year-over-year to -$14.2 million; the trailing twelve-month figure through Mar 2026 stood at -$84.1 million (up 39.89% YoY), and the FY2025 full-year result was -$104.6 million, up 25.16% from the prior year.
- Operating Income advanced to -$14.2 million in Q1 2026, from -$17.3 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of -$14.2 million in Q1 2026 to a low of -$37.4 million in Q4 2023.
- A 5-year average of -$30.3 million and a median of -$32.4 million in 2023 frame the typical range for Operating Income.
- Across the five-year window, Operating Income slumped 37.88% in 2022 and jumped 59.03% in 2026, its largest moves.
- Tracing PRLD's Operating Income over 5 years: stood at -$33.4 million in 2022, then decreased by 11.96% to -$37.4 million in 2023, then grew by 9.49% to -$33.8 million in 2024, then surged by 48.72% to -$17.3 million in 2025, then climbed by 18.28% to -$14.2 million in 2026.
- Business Quant data shows PRLD's Operating Income at -$14.2 million in Q1 2026, -$17.3 million in Q4 2025, and -$20.4 million in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Prelude Therapeutics | 318.53 Mn | 173.93 Mn | - | -14.18 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -14.18 Mn |
| Dec 31, 2025 | -17.35 Mn |
| Sep 30, 2025 | -20.42 Mn |
| Jun 30, 2025 | -32.19 Mn |
| Mar 31, 2025 | -34.61 Mn |
| Dec 31, 2024 | -33.83 Mn |
| Sep 30, 2024 | -34.38 Mn |
| Jun 30, 2024 | -37.16 Mn |
| Mar 31, 2024 | -34.34 Mn |
| Dec 31, 2023 | -37.38 Mn |
| Sep 30, 2023 | -33.39 Mn |
| Jun 30, 2023 | -32.40 Mn |
| Mar 31, 2023 | -29.12 Mn |
| Dec 31, 2022 | -33.39 Mn |
| Sep 30, 2022 | -30.41 Mn |
| Jun 30, 2022 | -29.46 Mn |
| Mar 31, 2022 | -30.29 Mn |
| Dec 31, 2021 | -33.01 Mn |
| Sep 30, 2021 | -30.84 Mn |
| Jun 30, 2021 | -27.92 Mn |