Prelude Therapeutics (PRLD) Operating Income (2019 - 2026)

Prelude Therapeutics (PRLD) reported Operating Income of -$14.2 million for Q1 2026, up 59.03% on a YoY basis from -$8.9 million in Q1 2025, and up 18.28% sequentially from -$17.3 million in Q4 2025.

Prelude Therapeutics (PRLD) Operating Income (2019 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 8 years of Operating Income data on file, last reported at -$14.2 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income rose 59.03% year-over-year to -$14.2 million; the trailing twelve-month figure through Mar 2026 stood at -$84.1 million (up 39.89% YoY), and the FY2025 full-year result was -$104.6 million, up 25.16% from the prior year.
  • Operating Income advanced to -$14.2 million in Q1 2026, from -$17.3 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$14.2 million in Q1 2026 to a low of -$37.4 million in Q4 2023.
  • A 5-year average of -$30.3 million and a median of -$32.4 million in 2023 frame the typical range for Operating Income.
  • Across the five-year window, Operating Income slumped 37.88% in 2022 and jumped 59.03% in 2026, its largest moves.
  • Tracing PRLD's Operating Income over 5 years: stood at -$33.4 million in 2022, then decreased by 11.96% to -$37.4 million in 2023, then grew by 9.49% to -$33.8 million in 2024, then surged by 48.72% to -$17.3 million in 2025, then climbed by 18.28% to -$14.2 million in 2026.
  • Business Quant data shows PRLD's Operating Income at -$14.2 million in Q1 2026, -$17.3 million in Q4 2025, and -$20.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Prelude Therapeutics 318.53 Mn 173.93 Mn - -14.18 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -14.18 Mn
Dec 31, 2025 -17.35 Mn
Sep 30, 2025 -20.42 Mn
Jun 30, 2025 -32.19 Mn
Mar 31, 2025 -34.61 Mn
Dec 31, 2024 -33.83 Mn
Sep 30, 2024 -34.38 Mn
Jun 30, 2024 -37.16 Mn
Mar 31, 2024 -34.34 Mn
Dec 31, 2023 -37.38 Mn
Sep 30, 2023 -33.39 Mn
Jun 30, 2023 -32.40 Mn
Mar 31, 2023 -29.12 Mn
Dec 31, 2022 -33.39 Mn
Sep 30, 2022 -30.41 Mn
Jun 30, 2022 -29.46 Mn
Mar 31, 2022 -30.29 Mn
Dec 31, 2021 -33.01 Mn
Sep 30, 2021 -30.84 Mn
Jun 30, 2021 -27.92 Mn