Prelude Therapeutics (PRLD) EBT (2019 - 2026)

Prelude Therapeutics (PRLD) reported EBT of -$34.4 million for Q1 2026, up 40.15% on a YoY basis from -$24.6 million in Q1 2025, and down 90.49% sequentially from -$18.1 million in Q4 2025.

Prelude Therapeutics (PRLD) EBT (2019 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 8 years of EBT data on file, last reported at -$34.4 million in Q1 2026.

  • For the quarter ending Q1 2026, EBT rose 40.15% year-over-year to -$34.4 million; the trailing twelve-month figure through Mar 2026 stood at -$149.0 million (up 39.97% YoY), and the FY2025 full-year result was -$316.5 million, up 1.83% from the prior year.
  • EBT retreated to -$34.4 million in Q1 2026, from -$18.1 million in the prior quarter.
  • In the past five years, EBT ranged from a high of -$18.1 million in Q4 2025 to a low of -$144.4 million in Q4 2022.
  • A 5-year average of -$52.4 million and a median of -$41.6 million in 2022 frame the typical range for EBT.
  • Across the five-year window, EBT surged 83.64% in 2022 and slumped 112.54% in 2024, its largest moves.
  • Tracing PRLD's EBT over 5 years: stood at -$144.4 million in 2022, then jumped by 73.79% to -$37.9 million in 2023, then grew by 9.24% to -$34.4 million in 2024, then surged by 47.38% to -$18.1 million in 2025, then plunged by 90.49% to -$34.4 million in 2026.
  • Business Quant data shows PRLD's EBT at -$34.4 million in Q1 2026, -$18.1 million in Q4 2025, and -$42.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Prelude Therapeutics 318.53 Mn 173.93 Mn - -34.44 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -34.44 Mn
Dec 31, 2025 -18.08 Mn
Sep 30, 2025 -42.02 Mn
Jun 30, 2025 -54.47 Mn
Mar 31, 2025 -57.55 Mn
Dec 31, 2024 -34.36 Mn
Sep 30, 2024 -76.48 Mn
Jun 30, 2024 -79.85 Mn
Mar 31, 2024 -77.64 Mn
Dec 31, 2023 -37.86 Mn
Sep 30, 2023 -35.99 Mn
Jun 30, 2023 -37.80 Mn
Mar 31, 2023 -38.22 Mn
Dec 31, 2022 -144.44 Mn
Sep 30, 2022 -42.51 Mn
Jun 30, 2022 -37.16 Mn
Mar 31, 2022 -41.59 Mn
Dec 31, 2021 -108.38 Mn
Sep 30, 2021 -170.14 Mn
Jun 30, 2021 -159.02 Mn