Prelude Therapeutics (PRLD) EBITDA (2019 - 2026)
Prelude Therapeutics' (PRLD) quarterly EBITDA came in at -$10.4 million in Q1 2026, up 67.5% year-on-year from -$6.2 million in Q1 2025, and up 36.58% quarter-over-quarter from -$16.5 million in Q4 2025.
Prelude Therapeutics (PRLD) EBITDA (2019 - 2026) Analysis & Trends
Prelude Therapeutics has disclosed EBITDA across 8 years of filings, most recently posting -$10.4 million for Q1 2026.
- EBITDA for Q1 2026 came in at -$10.4 million, up 67.5% year-over-year; the trailing twelve-month figure through Mar 2026 was -$77.9 million (up 38.98% YoY), and the FY2025 annual result was -$99.5 million, up 21.86% from the prior year.
- EBITDA came in at -$10.4 million for Q1 2026 at Prelude Therapeutics, up from -$16.5 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$10.4 million in Q1 2026 to a low of -$34.8 million in Q2 2024.
- The 5-year median for EBITDA is -$30.5 million (2023), against an average of -$27.9 million.
- Across the five-year window, EBITDA slumped 45.85% in 2022 and jumped 67.5% in 2026, its largest moves.
- Prelude Therapeutics' EBITDA stood at -$28.0 million in 2022, then declined by 15.29% to -$32.2 million in 2023, then gained by 10.49% to -$28.9 million in 2024, then soared by 43.0% to -$16.5 million in 2025, then surged by 36.58% to -$10.4 million in 2026.
- The last three EBITDA figures came in at -$10.4 million (Q1 2026), -$16.5 million (Q4 2025), and -$19.7 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | - |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | -14.44 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -3.82 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -65.83 Mn |
| 10 | Prelude Therapeutics | 314.40 Mn | 169.80 Mn | - | -10.43 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -10.43 Mn |
| Dec 31, 2025 | -16.45 Mn |
| Sep 30, 2025 | -19.72 Mn |
| Jun 30, 2025 | -31.24 Mn |
| Mar 31, 2025 | -32.11 Mn |
| Dec 31, 2024 | -28.86 Mn |
| Sep 30, 2024 | -31.81 Mn |
| Jun 30, 2024 | -34.80 Mn |
| Mar 31, 2024 | -31.89 Mn |
| Dec 31, 2023 | -32.25 Mn |
| Sep 30, 2023 | -30.50 Mn |
| Jun 30, 2023 | -30.74 Mn |
| Mar 31, 2023 | -26.42 Mn |
| Dec 31, 2022 | -27.97 Mn |
| Sep 30, 2022 | -30.03 Mn |
| Jun 30, 2022 | -27.36 Mn |
| Mar 31, 2022 | -31.07 Mn |
| Dec 31, 2021 | -33.38 Mn |
| Sep 30, 2021 | -30.86 Mn |
| Jun 30, 2021 | -26.87 Mn |