PDS Biotechnology PDSB
NASDAQ PDSB
$0.22 +0.01 (+4.32%)
As of: Aug 21, 2026 · 10:27 AM EDT

PDS Biotechnology (PDSB) Operating Income (2014 - 2026)

PDS Biotechnology's (PDSB) quarterly Operating Income came in at -$6.7 million in Q4 2025, up 9.32% YoY from -$6.1 million in Q4 2024, and up 18.0% on a QoQ basis from -$8.1 million in Q3 2025.

PDS Biotechnology (PDSB) Operating Income (2014 - 2026) Analysis & Trends

PDS Biotechnology (PDSB) has 12 years of Operating Income data on file, last reported at -$6.7 million in Q4 2025.

  • Quarterly Operating Income rose 9.32% year-over-year to -$6.7 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$31.5 million (up 13.15% YoY) and the FY2025 annual result came in at -$31.5 million, up 13.15% from the prior year.
  • Operating Income climbed to -$6.7 million in Q4 2025, from -$8.1 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of -$3.0 million in Q1 2021 to a low of -$18.8 million in Q4 2022.
  • A 5-year average of -$8.7 million and a median of -$8.3 million in 2022 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2022 — Operating Income slumped 197.73% — and 2023, when it jumped 44.71%.
  • Tracing PDSB's Operating Income over 5 years: stood at -$6.3 million in 2021, then slumped by 197.73% to -$18.8 million in 2022, then jumped by 44.71% to -$10.4 million in 2023, then climbed by 29.27% to -$7.4 million in 2024, then climbed by 9.32% to -$6.7 million in 2025.
  • The last three Operating Income figures came in at -$6.7 million (Q4 2025), -$8.1 million (Q3 2025), and -$7.6 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 140.52 Bn 132.67 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 86.54 Bn 78.55 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 65.31 Bn 60.13 Bn 1.37 Bn 493.00 Mn
4 Moderna 61.77 Bn 56.64 Bn 52.00 Mn -815.00 Mn
5 BeOne Medicines 42.26 Bn 37.16 Bn 1.53 Bn 325.05 Mn
6 Alnylam Pharmaceuticals 31.19 Bn 27.88 Bn 992.69 Mn 231.44 Mn
7 BioNTech SE 28.71 Bn 10.31 Bn 668.28 Mn -375.75 Mn
8 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -1.55 Mn
9 Royalty Pharma 27.35 Bn 26.52 Bn - 133.12 Mn
10 PDS Biotechnology 11.97 Mn 11.97 Mn - -6.50 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -6.50 Mn
Dec 31, 2025 -6.67 Mn
Sep 30, 2025 -8.14 Mn
Jun 30, 2025 -7.62 Mn
Mar 31, 2025 -9.11 Mn
Dec 31, 2024 -7.36 Mn
Sep 30, 2024 -10.18 Mn
Jun 30, 2024 -8.68 Mn
Mar 31, 2024 -10.10 Mn
Dec 31, 2023 -10.41 Mn
Sep 30, 2023 -10.52 Mn
Jun 30, 2023 -12.70 Mn
Mar 31, 2023 -9.42 Mn
Dec 31, 2022 -18.82 Mn
Sep 30, 2022 -7.28 Mn
Jun 30, 2022 -7.09 Mn
Mar 31, 2022 -8.48 Mn
Dec 31, 2021 -6.32 Mn
Sep 30, 2021 -6.96 Mn
Jun 30, 2021 -5.11 Mn