Puma Biotechnology (PBYI) Operating Income (2010 - 2026)
Puma Biotechnology's (PBYI) quarterly Operating Income came in at -$3.8 million in Q1 2026, down 196.08% YoY from $4.0 million in Q1 2025, and down 122.38% on a QoQ basis from $17.1 million in Q4 2025.
Analysis
Puma Biotechnology (PBYI) Operating Income (2010 - 2026) Analysis & Trends
Puma Biotechnology (PBYI) has 17 years of Operating Income data on file, last reported at -$3.8 million in Q1 2026.
- Quarterly Operating Income fell 196.08% year-over-year to -$3.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $29.5 million (down 20.84% YoY) and the FY2025 annual result came in at $37.3 million, up 20.45% from the prior year.
- Operating Income retreated to -$3.8 million in Q1 2026, from $17.1 million in the prior quarter.
- In the past five years, Operating Income ranged from a high of $22.1 million in Q3 2024 to a low of -$3.8 million in Q1 2026.
- A 5-year average of $7.1 million and a median of $6.6 million in 2025 frame the typical range for Operating Income.
- Annual changes were most pronounced in 2023 — Operating Income surged 684.34% — and 2026, when it tumbled 196.08%.
- Tracing PBYI's Operating Income over 5 years: stood at $10.0 million in 2022, then soared by 47.74% to $14.8 million in 2023, then decreased by 9.68% to $13.4 million in 2024, then climbed by 27.99% to $17.1 million in 2025, then sank by 122.38% to -$3.8 million in 2026.
- The last three Operating Income figures came in at -$3.8 million (Q1 2026), $17.1 million (Q4 2025), and $9.6 million (Q3 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 493.00 Mn |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -815.00 Mn |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | -505.13 Mn |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 325.05 Mn |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 133.12 Mn |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Puma Biotechnology | 486.99 Mn | 393.08 Mn | 44.03 Mn | 7.59 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 7.59 Mn |
| Mar 31, 2026 | -3.83 Mn |
| Dec 31, 2025 | 17.11 Mn |
| Sep 30, 2025 | 9.57 Mn |
| Jun 30, 2025 | 6.64 Mn |
| Mar 31, 2025 | 3.98 Mn |
| Dec 31, 2024 | 13.37 Mn |
| Sep 30, 2024 | 22.08 Mn |
| Jun 30, 2024 | -2.18 Mn |
| Mar 31, 2024 | -2.30 Mn |
| Dec 31, 2023 | 14.80 Mn |
| Sep 30, 2023 | 8.59 Mn |
| Jun 30, 2023 | 4.89 Mn |
| Mar 31, 2023 | 4.37 Mn |
| Dec 31, 2022 | 10.02 Mn |
| Sep 30, 2022 | 2.39 Mn |
| Jun 30, 2022 | 12.06 Mn |
| Mar 31, 2022 | -747,000.00 |
| Dec 31, 2021 | 6.83 Mn |
| Sep 30, 2021 | -8.95 Mn |