Puma Biotechnology (PBYI) Operating Income (2010 - 2026)
Puma Biotechnology (PBYI) reported Operating Income of -$3.8 million for Q1 2026, down 196.08% on a YoY basis from $4.0 million in Q1 2025, and down 122.38% quarter-over-quarter from $17.1 million in Q4 2025.
Puma Biotechnology (PBYI) Operating Income (2010 - 2026) Analysis & Trends
Puma Biotechnology has reported Operating Income for 17 years, with the latest figure at -$3.8 million in Q1 2026.
- For the quarter ending Q1 2026, Operating Income fell 196.08% year-over-year to -$3.8 million; the trailing twelve-month figure through Mar 2026 stood at $29.5 million (down 20.84% YoY), and the FY2025 full-year result was $37.3 million, up 20.45% from the prior year.
- Operating Income for Q1 2026 stood at -$3.8 million, down from $17.1 million in the prior quarter.
- The five-year high for Operating Income was $22.1 million in Q3 2024, with the low at -$3.8 million in Q1 2026.
- Historically, Operating Income has averaged $7.1 million across 5 years, with a median of $6.6 million in 2025.
- Annual changes were most pronounced in 2022 — Operating Income soared 2091.25% — and 2026, when it tumbled 196.08%.
- Puma Biotechnology's Operating Income stood at $10.0 million in 2022, then soared by 47.74% to $14.8 million in 2023, then decreased by 9.68% to $13.4 million in 2024, then climbed by 27.99% to $17.1 million in 2025, then sank by 122.38% to -$3.8 million in 2026.
- The last three Operating Income figures came in at -$3.8 million (Q1 2026), $17.1 million (Q4 2025), and $9.6 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Puma Biotechnology | 384.39 Mn | 282.84 Mn | 34.39 Mn | -3.83 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -3.83 Mn |
| Dec 31, 2025 | 17.11 Mn |
| Sep 30, 2025 | 9.57 Mn |
| Jun 30, 2025 | 6.64 Mn |
| Mar 31, 2025 | 3.98 Mn |
| Dec 31, 2024 | 13.37 Mn |
| Sep 30, 2024 | 22.08 Mn |
| Jun 30, 2024 | -2.18 Mn |
| Mar 31, 2024 | -2.30 Mn |
| Dec 31, 2023 | 14.80 Mn |
| Sep 30, 2023 | 8.59 Mn |
| Jun 30, 2023 | 4.89 Mn |
| Mar 31, 2023 | 4.37 Mn |
| Dec 31, 2022 | 10.02 Mn |
| Sep 30, 2022 | 2.39 Mn |
| Jun 30, 2022 | 12.06 Mn |
| Mar 31, 2022 | -747,000.00 |
| Dec 31, 2021 | -503,000.00 |
| Sep 30, 2021 | -8.95 Mn |
| Jun 30, 2021 | -16.63 Mn |