Puma Biotechnology PBYI
NASDAQ PBYI
$9.55 +0.14 (+1.49%)
As of: Sep 4, 2026 · 3:59 PM EDT

Puma Biotechnology (PBYI) Operating Income (2010 - 2026)

Puma Biotechnology's (PBYI) quarterly Operating Income came in at -$3.8 million in Q1 2026, down 196.08% YoY from $4.0 million in Q1 2025, and down 122.38% on a QoQ basis from $17.1 million in Q4 2025.

Analysis

Puma Biotechnology (PBYI) Operating Income (2010 - 2026) Analysis & Trends

Puma Biotechnology (PBYI) has 17 years of Operating Income data on file, last reported at -$3.8 million in Q1 2026.

  • Quarterly Operating Income fell 196.08% year-over-year to -$3.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $29.5 million (down 20.84% YoY) and the FY2025 annual result came in at $37.3 million, up 20.45% from the prior year.
  • Operating Income retreated to -$3.8 million in Q1 2026, from $17.1 million in the prior quarter.
  • In the past five years, Operating Income ranged from a high of $22.1 million in Q3 2024 to a low of -$3.8 million in Q1 2026.
  • A 5-year average of $7.1 million and a median of $6.6 million in 2025 frame the typical range for Operating Income.
  • Annual changes were most pronounced in 2023 — Operating Income surged 684.34% — and 2026, when it tumbled 196.08%.
  • Tracing PBYI's Operating Income over 5 years: stood at $10.0 million in 2022, then soared by 47.74% to $14.8 million in 2023, then decreased by 9.68% to $13.4 million in 2024, then climbed by 27.99% to $17.1 million in 2025, then sank by 122.38% to -$3.8 million in 2026.
  • The last three Operating Income figures came in at -$3.8 million (Q1 2026), $17.1 million (Q4 2025), and $9.6 million (Q3 2025), per Business Quant data.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 493.00 Mn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -815.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -505.13 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 325.05 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 231.44 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 133.12 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -1.55 Mn
10 Puma Biotechnology 486.99 Mn 393.08 Mn 44.03 Mn 7.59 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 7.59 Mn
Mar 31, 2026 -3.83 Mn
Dec 31, 2025 17.11 Mn
Sep 30, 2025 9.57 Mn
Jun 30, 2025 6.64 Mn
Mar 31, 2025 3.98 Mn
Dec 31, 2024 13.37 Mn
Sep 30, 2024 22.08 Mn
Jun 30, 2024 -2.18 Mn
Mar 31, 2024 -2.30 Mn
Dec 31, 2023 14.80 Mn
Sep 30, 2023 8.59 Mn
Jun 30, 2023 4.89 Mn
Mar 31, 2023 4.37 Mn
Dec 31, 2022 10.02 Mn
Sep 30, 2022 2.39 Mn
Jun 30, 2022 12.06 Mn
Mar 31, 2022 -747,000.00
Dec 31, 2021 6.83 Mn
Sep 30, 2021 -8.95 Mn