Puma Biotechnology (PBYI) Net Income (2010 - 2026)

Puma Biotechnology (PBYI) posted Net Income of -$3.8 million for Q1 2026, down 122.26% on a QoQ basis from $16.9 million in Q4 2025, and down 226.19% year-over-year from $3.0 million in Q1 2025.

Puma Biotechnology (PBYI) Net Income (2010 - 2026) Analysis & Trends

Puma Biotechnology's Net Income history runs 17 years deep, the most recent figure standing at -$3.8 million for Q1 2026.

  • Quarterly Net Income fell 226.19% year-over-year to -$3.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $27.8 million (up 265.22% YoY) and the FY2025 annual result came in at $34.5 million, up 19834.29% from the prior year.
  • Net Income was -$3.8 million for Q1 2026 at Puma Biotechnology, down from $16.9 million in the prior quarter.
  • Across five years, Net Income topped out at $20.3 million in Q3 2024 and bottomed at -$11.1 million in Q4 2024.
  • A 5-year average of $3.1 million and a median of $2.1 million in 2023 frame the typical range for Net Income.
  • Annual changes were most pronounced in 2023 — Net Income surged 1710.0% — and 2024, when it sank 443.68%.
  • Puma Biotechnology's Net Income stood at -$5.2 million in 2022, then soared by 341.62% to $12.4 million in 2023, then slumped by 189.57% to -$11.1 million in 2024, then soared by 251.26% to $16.9 million in 2025, then slumped by 122.26% to -$3.8 million in 2026.
  • Business Quant data shows PBYI's Net Income at -$3.8 million in Q1 2026, $16.9 million in Q4 2025, and $8.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -37.09 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 227.36 Mn
4 NuCana 279.75 Bn 279.75 Bn - -3.31 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -26.94 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 362.00 Mn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -453.82 Mn
10 Puma Biotechnology 407.27 Mn 368.99 Mn 34.39 Mn -3.75 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -3.75 Mn
Dec 31, 2025 16.86 Mn
Sep 30, 2025 8.84 Mn
Jun 30, 2025 5.86 Mn
Mar 31, 2025 2.97 Mn
Dec 31, 2024 -11.15 Mn
Sep 30, 2024 20.32 Mn
Jun 30, 2024 -4.53 Mn
Mar 31, 2024 -4.82 Mn
Dec 31, 2023 12.45 Mn
Sep 30, 2023 5.80 Mn
Jun 30, 2023 2.13 Mn
Mar 31, 2023 1.40 Mn
Dec 31, 2022 -5.15 Mn
Sep 30, 2022 -360,000.00
Jun 30, 2022 9.37 Mn
Mar 31, 2022 -3.40 Mn
Dec 31, 2021 4.22 Mn
Sep 30, 2021 -44.67 Mn
Jun 30, 2021 -5.11 Mn