Puma Biotechnology (PBYI) Gross Profit (2017 - 2026)

Puma Biotechnology (PBYI) posted Gross Profit of $34.4 million for Q1 2026, down 34.28% on a QoQ basis from $52.3 million in Q4 2025, and down 2.99% year-over-year from $35.5 million in Q1 2025.

Puma Biotechnology (PBYI) Gross Profit (2017 - 2026) Analysis & Trends

Puma Biotechnology's Gross Profit history runs 10 years deep, the most recent figure standing at $34.4 million for Q1 2026.

  • Quarterly Gross Profit fell 2.99% year-over-year to $34.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $169.2 million (changed 0.4% YoY) and the FY2025 annual result came in at $170.2 million, up 2.5% from the prior year.
  • Gross Profit was $34.4 million for Q1 2026 at Puma Biotechnology, down from $52.3 million in the prior quarter.
  • Across five years, Gross Profit topped out at $70.8 million in Q4 2022 and bottomed at $33.0 million in Q1 2024.
  • A 5-year average of $43.4 million and a median of $42.7 million in 2023 frame the typical range for Gross Profit.
  • Peak annual rise in Gross Profit reached 62.92% in 2022, while the deepest fall reached 49.15% in 2022.
  • Puma Biotechnology's Gross Profit stood at $70.8 million in 2022, then slumped by 32.42% to $47.9 million in 2023, then declined by 5.64% to $45.2 million in 2024, then advanced by 15.88% to $52.3 million in 2025, then plunged by 34.28% to $34.4 million in 2026.
  • Business Quant data shows PBYI's Gross Profit at $34.4 million in Q1 2026, $52.3 million in Q4 2025, and $42.3 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn
4 NuCana 279.75 Bn 279.75 Bn -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn
7 Belite Bio 62.51 Bn 62.51 Bn -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn -
10 Puma Biotechnology 407.27 Mn 368.99 Mn 34.39 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 34.39 Mn
Mar 31, 2026 34.39 Mn
Dec 31, 2025 52.33 Mn
Dec 31, 2025 52.33 Mn
Sep 30, 2025 42.30 Mn
Sep 30, 2025 42.30 Mn
Jun 30, 2025 40.14 Mn
Jun 30, 2025 40.14 Mn
Mar 31, 2025 35.45 Mn
Mar 31, 2025 35.45 Mn
Dec 31, 2024 45.16 Mn
Dec 31, 2024 45.16 Mn
Sep 30, 2024 51.45 Mn
Sep 30, 2024 51.45 Mn
Jun 30, 2024 36.43 Mn
Jun 30, 2024 36.43 Mn
Mar 31, 2024 33.04 Mn
Mar 31, 2024 33.04 Mn
Dec 31, 2023 47.86 Mn
Dec 31, 2023 47.86 Mn