Puma Biotechnology (PBYI) EBIT (2010 - 2026)

Puma Biotechnology (PBYI) posted EBIT of -$3.8 million for Q1 2026, down 122.38% on a QoQ basis from $17.1 million in Q4 2025, and down 196.08% year-over-year from $4.0 million in Q1 2025.

Puma Biotechnology (PBYI) EBIT (2010 - 2026) Analysis & Trends

Puma Biotechnology's EBIT history runs 17 years deep, the most recent figure standing at -$3.8 million for Q1 2026.

  • Quarterly EBIT fell 196.08% year-over-year to -$3.8 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $29.5 million (down 20.84% YoY) and the FY2025 annual result came in at $37.3 million, up 20.45% from the prior year.
  • EBIT was -$3.8 million for Q1 2026 at Puma Biotechnology, down from $17.1 million in the prior quarter.
  • Across five years, EBIT topped out at $22.1 million in Q3 2024 and bottomed at -$3.8 million in Q1 2026.
  • A 5-year average of $7.1 million and a median of $6.6 million in 2025 frame the typical range for EBIT.
  • Annual changes were most pronounced in 2023 — EBIT surged 684.34% — and 2026, when it slumped 196.08%.
  • Puma Biotechnology's EBIT stood at $10.0 million in 2022, then surged by 47.74% to $14.8 million in 2023, then dropped by 9.68% to $13.4 million in 2024, then increased by 27.99% to $17.1 million in 2025, then tumbled by 122.38% to -$3.8 million in 2026.
  • Business Quant data shows PBYI's EBIT at -$3.8 million in Q1 2026, $17.1 million in Q4 2025, and $9.6 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -27.75 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 249.90 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.14 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 642.90 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 394.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -445.22 Mn
10 Puma Biotechnology 406.51 Mn 368.22 Mn 34.39 Mn -3.83 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -3.83 Mn
Dec 31, 2025 17.11 Mn
Sep 30, 2025 9.57 Mn
Jun 30, 2025 6.64 Mn
Mar 31, 2025 3.98 Mn
Dec 31, 2024 13.37 Mn
Sep 30, 2024 22.08 Mn
Jun 30, 2024 -2.18 Mn
Mar 31, 2024 -2.30 Mn
Dec 31, 2023 14.80 Mn
Sep 30, 2023 8.59 Mn
Jun 30, 2023 4.89 Mn
Mar 31, 2023 4.37 Mn
Dec 31, 2022 10.02 Mn
Sep 30, 2022 2.39 Mn
Jun 30, 2022 12.06 Mn
Mar 31, 2022 -747,000.00
Dec 31, 2021 6.83 Mn
Sep 30, 2021 -8.95 Mn
Jun 30, 2021 -16.63 Mn