Growth Metrics

Omeros (OMER) Return on Capital Employed (2011 - 2026)

Omeros recorded quarterly Return on Capital Employed of 42.7% in Q1 2026, up 38.23% quarter-over-quarter from 69.14% in Q4 2025, and up 5151.0% year-over-year from 0.81% in Q1 2025.

Omeros' Return on Capital Employed history runs 16 years deep, the most recent figure standing at 42.7% for Q1 2026.

  • In Q1 2026, Return on Capital Employed rose 5151.0% year-over-year to 42.7%; the TTM figure through Mar 2026 stood at 42.7% (up 5151.0% YoY), while the FY2025 annual figure was 54.99%, up 1229.0% from the prior year.
  • Return on Capital Employed came in at 42.7% for Q1 2026 at Omeros, up from 69.14% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 37.6% in Q1 2023 to a low of 113.07% in Q3 2025.
  • A 5-year average of 59.69% and a median of 48.12% in 2024 frame the typical range for Return on Capital Employed.
  • Across the five-year window, Return on Capital Employed soared 13376 bps in 2022 and tumbled 5098 bps in 2025, its largest moves.
  • Omeros' Return on Capital Employed stood at 42.12% in 2022, then declined by 2 bps to 43.03% in 2023, then sank by 80 bps to 77.41% in 2024, then rose by 11 bps to 69.14% in 2025, then soared by 38 bps to 42.7% in 2026.
  • According to Business Quant data, Return on Capital Employed over the past three periods registered 42.7%, 69.14%, and 113.07% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - 450.31%
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn 51.73%
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -107.40%
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 21.10%
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 10.19%
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 20.34%
10 Omeros 772.03 Mn 636.71 Mn 9.31 Mn -42.70%

Historic Data

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DateValue
Mar 31, 2026 -42.70%
Dec 31, 2025 -69.14%
Sep 30, 2025 -113.07%
Jun 30, 2025 -102.81%
Mar 31, 2025 -94.21%
Dec 31, 2024 -77.41%
Sep 30, 2024 -62.09%
Jun 30, 2024 -55.16%
Mar 31, 2024 -48.12%
Dec 31, 2023 -43.03%
Sep 30, 2023 -45.42%
Jun 30, 2023 -41.85%
Mar 31, 2023 -37.60%
Dec 31, 2022 -42.12%
Sep 30, 2022 -45.88%
Jun 30, 2022 -48.66%
Mar 31, 2022 -45.48%
Dec 31, 2021 -79.07%
Sep 30, 2021 -179.65%
Jun 30, 2021 -142.02%
Mar 31, 2021 -103.45%
Dec 31, 2020 -66.10%
Sep 30, 2020 -99.33%
Jun 30, 2020 -152.76%
Mar 31, 2020 -97.36%
Dec 31, 2019 -108.06%
Sep 30, 2019 -132.89%
Jun 30, 2019 -150.45%
Mar 31, 2019 -191.86%
Dec 31, 2018 -231.78%
Sep 30, 2018 -162.47%
Jun 30, 2018 -105.85%
Mar 31, 2018 -75.41%
Dec 31, 2017 -46.39%
Sep 30, 2017 -61.00%
Jun 30, 2017 -140.24%
Mar 31, 2017 -103.66%
Dec 31, 2016 -100.61%
Sep 30, 2016 -139.38%
Jun 30, 2016 -271.16%
Mar 31, 2016 -291.48%
Dec 31, 2015 -246.05%
Sep 30, 2015 -263.65%
Jun 30, 2015 -152.11%
Mar 31, 2015 -316.84%
Dec 31, 2014 27,891.63%
Sep 30, 2014 -341.05%
Jun 30, 2014 -165.67%
Mar 31, 2014 -215.51%
Dec 31, 2013 -2,103.52%
Sep 30, 2013 -783.30%
Jun 30, 2013 -461.71%
Mar 31, 2013 -336.25%
Dec 31, 2012 -173.10%
Sep 30, 2012 9,861.38%
Jun 30, 2012 1,934.01%
Mar 31, 2012 -548.45%
Dec 31, 2011 -228.45%
Sep 30, 2011 -117.92%