Omeros Corp (OMER) Institutional Ownership

Institutions by Trading Activity

Ownership Statistics

59,684,236Shares Outstanding

508,369Shares held by institutions

$6,064,842Value of institutional holdings

56.00%Institutional ownership %

2.56%Shares Changed QoQ

144No. of institutional investors

Shares Owned by Institutions

Shares Purchased/Sold by Institutions

Ownership Summary

Omeros Corp (NASDAQ:OMER) currently has 144 active institutional owners and shareholders as of today (December 2025), that have filed 13F forms with the Securities Exchange Commission (SEC).

Institutional ownership in Omeros edged down to 56.0% in December 2025, compared to 58.8% in September 2025.
Quarterly data indicates a 2.56% shift in institutional share volume, and the annual owner count reflects an increase of 9.92%.
Of these 144 institutional investors, 88 increased their holdings in Omeros, while 35 of them reduced positions, and 21 investors maintained their exposure.
The total number of shares held by institutions in Omeros increased to 33.42Mn as of December 2025, a net change of up by 833.85K shares quarter on quarter, and up 6.25Mn shares year over year.
BlackRock, Inc.'s holding of 5.06Mn shares as of December 31, 2025 makes it the primary institutional investor in Omeros, owning 8.48% of the stock.
Among the most significant buyers of Omeros during December 2025 were UBS Group AG (1.51Mn), KOTLER KEVIN (905.63K), VANGUARD GROUP INC (666.36K), SUSQUEHANNA INTERNATIONAL GROUP, LLP (631.32K), NOMURA HOLDINGS INC (611.34K).
Leading sellers of Omeros stock in December 2025 included Polar Asset Management Partners Inc. (2.93Mn), MORGAN STANLEY (1.60Mn), INGALLS & SNYDER LLC (700.90K), TWO SIGMA ADVISERS, LP (502.10K), TWO SIGMA INVESTMENTS, LP (408.56K).
The top 10 institutional holders of Omeros for the quarter ending December 2025 included BlackRock, Inc. (5.06Mn), VANGUARD GROUP INC (4.01Mn), INGALLS & SNYDER LLC (3.45Mn), UBS Group AG (2.22Mn), STIFEL FINANCIAL CORP (1.81Mn), GEODE CAPITAL MANAGEMENT, LLC (1.63Mn), STATE STREET CORP (1.57Mn), KOTLER KEVIN (905.63K), D. E. Shaw & Co., Inc. (755.00K), JANE STREET GROUP, LLC (744.22K).

144 Institutional Holders

508,369 Total Shares Held

Rows:

Download Data

Owner Name	Date	Shares Held	Change (QoQ)	Change (%)	Value (USD)
BlackRock, Inc.	31 Dec, 2025	5,062,438	610,282	13.71%	$86,947,374.00
VANGUARD GROUP INC	31 Dec, 2025	4,013,315	666,357	19.91%	$68,928,685.00
INGALLS & SNYDER LLC	31 Dec, 2025	3,448,699	-700,899	-16.89%	$59,231.00
UBS Group AG	31 Dec, 2025	2,222,982	1,513,893	213.50%	$38,179,715.00
STIFEL FINANCIAL CORP	31 Dec, 2025	1,809,766	-2,509	-0.14%	$31,082,740.00
GEODE CAPITAL MANAGEMENT, LLC	31 Dec, 2025	1,631,350	95,979	6.25%	$28,025,557.00
STATE STREET CORP	31 Dec, 2025	1,573,526	333,798	26.93%	$27,025,309.00
KOTLER KEVIN	31 Dec, 2025	905,635	905,635	0.00%	$15,554,281.00
D. E. Shaw & Co., Inc.	31 Dec, 2025	754,999	-250,236	-24.89%	$12,967,108.00
JANE STREET GROUP, LLC	31 Dec, 2025	744,222	411,035	123.36%	$12,782,013.00
SUSQUEHANNA INTERNATIONAL GROUP, LLP	31 Dec, 2025	741,895	631,316	570.92%	$12,742,047.00
NOMURA HOLDINGS INC	31 Dec, 2025	655,021	611,340	1,399.56%	$11,249,986.00
BANK OF MONTREAL /CAN/	31 Dec, 2025	601,643	38,548	6.85%	$10,333,219.00
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	31 Dec, 2025	593,222	39,755	7.18%	$10,188,588.00
NORTHERN TRUST CORP	31 Dec, 2025	526,732	-8,963	-1.67%	$9,046,622.00
TWO SIGMA INVESTMENTS, LP	31 Dec, 2025	524,757	-408,557	-43.77%	$9,012,701.00
ROYAL BANK OF CANADA	31 Dec, 2025	498,399	-45,277	-8.33%	$8,560,000.00
Caption Management, LLC	31 Dec, 2025	475,700	150,700	46.37%	$8,170,148.00
MILLENNIUM MANAGEMENT LLC	31 Dec, 2025	441,811	39,997	9.95%	$7,588,104.00
MORGAN STANLEY	31 Dec, 2025	386,152	-1,603,582	-80.59%	$6,632,161.00

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