OnKure Therapeutics OKUR
NASDAQ OKUR
$3.93 -0.15 (-3.68%)
At close: Aug 20, 2026 · 4:00 PM EDT

OnKure Therapeutics (OKUR) EBITDA (2020 - 2026)

OnKure Therapeutics' (OKUR) quarterly EBITDA came in at -$15.6 million in Q1 2026, up 8.15% YoY from -$14.4 million in Q1 2025, and down 10.55% on a QoQ basis from -$14.1 million in Q4 2025.

OnKure Therapeutics (OKUR) EBITDA (2020 - 2026) Analysis & Trends

OnKure Therapeutics (OKUR) has 7 years of EBITDA data on file, last reported at -$15.6 million in Q1 2026.

  • Quarterly EBITDA rose 8.15% year-over-year to -$15.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$61.6 million (changed 0.02% YoY) and the FY2025 annual result came in at -$63.0 million, down 15.75% from the prior year.
  • EBITDA retreated to -$15.6 million in Q1 2026, from -$14.1 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of $21.1 million in Q4 2023 to a low of -$21.0 million in Q2 2023.
  • A 5-year average of -$13.2 million and a median of -$14.6 million in 2022 frame the typical range for EBITDA.
  • Annual changes were most pronounced in 2023 — EBITDA surged 244.99% — and 2024, when it slumped 188.57%.
  • Tracing OKUR's EBITDA over 5 years: stood at -$14.6 million in 2022, then surged by 244.99% to $21.1 million in 2023, then tumbled by 188.57% to -$18.7 million in 2024, then rose by 24.46% to -$14.1 million in 2025, then retreated by 10.55% to -$15.6 million in 2026.
  • The last three EBITDA figures came in at -$15.6 million (Q1 2026), -$14.1 million (Q4 2025), and -$15.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 1.25 Bn
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 1.29 Bn
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn 493.00 Mn
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -815.00 Mn
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 325.05 Mn
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 231.44 Mn
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -1.55 Mn
8 Royalty Pharma 26.98 Bn 26.14 Bn - 133.12 Mn
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -375.75 Mn
10 OnKure Therapeutics 196.98 Mn 20.60 Mn - -16.90 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -16.90 Mn
Mar 31, 2026 -15.62 Mn
Dec 31, 2025 -14.13 Mn
Sep 30, 2025 -15.50 Mn
Jun 30, 2025 -16.32 Mn
Mar 31, 2025 -17.00 Mn
Dec 31, 2024 -18.70 Mn
Sep 30, 2024 -11.51 Mn
Jun 30, 2024 -14.34 Mn
Mar 31, 2024 -9.83 Mn
Dec 31, 2023 21.11 Mn
Sep 30, 2023 -20.89 Mn
Jun 30, 2023 -21.04 Mn
Mar 31, 2023 -16.12 Mn
Dec 31, 2022 -14.56 Mn
Sep 30, 2022 -13.84 Mn
Jun 30, 2022 -12.43 Mn
Mar 31, 2022 -13.02 Mn
Dec 31, 2021 -10.62 Mn
Sep 30, 2021 -12.75 Mn