Orchestra BioMed Holdings (OBIO) Operating Expenses (2021 - 2026)
Orchestra BioMed Holdings (OBIO) posted quarterly Operating Expenses of $22.2 million for Q1 2026, up 12.11% year-over-year from $19.8 million in Q1 2025, and down 8.18% quarter-over-quarter from $24.2 million in Q4 2025.
Orchestra BioMed Holdings (OBIO) Operating Expenses (2021 - 2026) Analysis & Trends
Orchestra BioMed Holdings (OBIO) has reported Operating Expenses for 6 consecutive years, with $22.2 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Expenses rose 12.11% year-over-year to $22.2 million; the TTM figure through Mar 2026 stood at $87.7 million (up 22.32% YoY), while the FY2025 annual figure was $85.3 million, up 27.41% from the prior year.
- Operating Expenses fell to $22.2 million in Q1 2026 per OBIO's latest filing, from $24.2 million in the prior quarter.
- Across five years, Operating Expenses topped out at $24.2 million in Q4 2025 and bottomed at $6.0 million in Q1 2022.
- Historically, Operating Expenses has averaged $15.6 million across 5 years, with a median of $15.0 million in 2024.
- Annual changes were most pronounced in 2022 — Operating Expenses surged 17517.86% — and 2026, when it climbed 12.11%.
- Orchestra BioMed Holdings' Operating Expenses stood at $10.9 million in 2022, then rose by 16.58% to $12.7 million in 2023, then soared by 32.86% to $16.9 million in 2024, then soared by 42.72% to $24.2 million in 2025, then decreased by 8.18% to $22.2 million in 2026.
- Business Quant data shows OBIO's Operating Expenses at $22.2 million in Q1 2026, $24.2 million in Q4 2025, and $21.2 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Opex (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 2.09 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 3.00 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 2.89 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | 505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 1.21 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | 4,978.15 |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 541.02 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 1.06 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | 427.03 Mn |
| 10 | Orchestra BioMed Holdings | 265.06 Mn | 80.63 Mn | 63,000.00 | 22.44 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | 22.44 Mn |
| Mar 31, 2026 | 22.19 Mn |
| Dec 31, 2025 | 24.16 Mn |
| Sep 30, 2025 | 21.17 Mn |
| Jun 30, 2025 | 20.16 Mn |
| Mar 31, 2025 | 19.79 Mn |
| Dec 31, 2024 | 16.93 Mn |
| Sep 30, 2024 | 17.33 Mn |
| Jun 30, 2024 | 17.64 Mn |
| Mar 31, 2024 | 15.04 Mn |
| Dec 31, 2023 | 12.74 Mn |
| Sep 30, 2023 | 14.94 Mn |
| Jun 30, 2023 | 13.87 Mn |
| Mar 31, 2023 | 12.71 Mn |
| Dec 31, 2022 | 10.93 Mn |
| Sep 30, 2022 | 11.23 Mn |
| Jun 30, 2022 | 8.04 Mn |
| Mar 31, 2022 | 5.99 Mn |
| Dec 31, 2021 | 62,045.00 |
| Sep 30, 2021 | 64,445.00 |