Orchestra BioMed Holdings (OBIO) Operating Expenses (2021 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Operating Expenses came in at $22.2 million in Q1 2026, up 12.11% year-on-year from $19.8 million in Q1 2025, and down 8.18% on a QoQ basis from $24.2 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Operating Expenses (2021 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 6 years of Operating Expenses data on file, last reported at $22.2 million in Q1 2026.

  • On a quarterly basis, Operating Expenses rose 12.11% year-over-year to $22.2 million in Q1 2026; TTM through Mar 2026 was $87.7 million, a 22.32% increase from a year earlier, with the FY2025 full-year figure at $85.3 million, up 27.41% from the prior year.
  • Operating Expenses for Q1 2026 stood at $22.2 million, down from $24.2 million in the prior quarter.
  • Over the last five years, Operating Expenses for OBIO reached as high as $24.2 million in Q4 2025 and fell as low as $6.0 million in Q1 2022.
  • Historically, Operating Expenses has averaged $15.6 million across 5 years, with a median of $15.0 million in 2024.
  • Across the five-year window, Operating Expenses soared 17517.86% in 2022 and gained 12.11% in 2026, its largest moves.
  • Year by year, Operating Expenses stood at $10.9 million in 2022, then advanced by 16.58% to $12.7 million in 2023, then surged by 32.86% to $16.9 million in 2024, then surged by 42.72% to $24.2 million in 2025, then dropped by 8.18% to $22.2 million in 2026.
  • Per Business Quant data, the three most recent Operating Expenses figures were $22.2 million in Q1 2026, $24.2 million in Q4 2025, and $21.2 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -28.01 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - 15.76 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 1.10 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.85 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 2.96 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - 32.68 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -919.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - 445.22 Mn
10 Orchestra BioMed Holdings 235.83 Mn 141.43 Mn 78,000.00 22.19 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 22.19 Mn
Dec 31, 2025 24.16 Mn
Sep 30, 2025 21.17 Mn
Jun 30, 2025 20.16 Mn
Mar 31, 2025 19.79 Mn
Dec 31, 2024 16.93 Mn
Sep 30, 2024 17.33 Mn
Jun 30, 2024 17.64 Mn
Mar 31, 2024 15.04 Mn
Dec 31, 2023 12.74 Mn
Sep 30, 2023 14.94 Mn
Jun 30, 2023 13.87 Mn
Mar 31, 2023 12.71 Mn
Dec 31, 2022 10.93 Mn
Sep 30, 2022 11.23 Mn
Jun 30, 2022 8.04 Mn
Mar 31, 2022 5.99 Mn
Dec 31, 2021 62,045.00
Sep 30, 2021 64,445.00
Jun 30, 2021 66,318.00