Orchestra BioMed Holdings (OBIO) Net Margin (2022 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Net Margin came in at 18778.18% in Q1 2026, down 1661747.0% year-on-year from N/an in Q1 2025, and down 90912.61% on a QoQ basis from 20.68% in Q4 2025.

Orchestra BioMed Holdings (OBIO) Net Margin (2022 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 5 years of Net Margin data on file, last reported at 18778.18% in Q1 2026.

  • On a quarterly basis, Net Margin fell 1661747.0% year-over-year to 18778.18% in Q1 2026; TTM through Mar 2026 was 172.26%, a 251877.0% increase from a year earlier, with the FY2025 full-year figure at 158.16%, up 215511.0% from the prior year.
  • Net Margin for Q1 2026 stood at 18778.18%, down from 20.68% in the prior quarter.
  • Over the last five years, Net Margin for OBIO reached as high as 20.68% in Q4 2025 and fell as low as 18778.18% in Q1 2026.
  • Historically, Net Margin has averaged 3353.61% across 5 years, with a median of 2160.71% in 2025.
  • Across the five-year window, Net Margin jumped 638352 bps in 2025 and plunged 1661747 bps in 2026, its largest moves.
  • Year by year, Net Margin stood at 921.03% in 2022, then slumped by 406 bps to 4656.49% in 2023, then tumbled by 37 bps to 6362.85% in 2024, then surged by 100 bps to 20.68% in 2025, then sank by 90913 bps to 18778.18% in 2026.
  • Per Business Quant data, the three most recent Net Margin figures were 18778.18% in Q1 2026, 20.68% in Q4 2025, and 2385.37% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 15.02%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 20.17%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 28.20%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Orchestra BioMed Holdings 235.83 Mn 141.43 Mn 78,000.00 -18,778.18%

Historic Data

Download Data
DateValue
Mar 31, 2026 -18,778.18%
Dec 31, 2025 20.68%
Sep 30, 2025 -2,385.37%
Jun 30, 2025 -2,579.90%
Mar 31, 2025 -2,160.71%
Dec 31, 2024 -6,362.85%
Sep 30, 2024 -1,785.41%
Jun 30, 2024 -3,237.53%
Mar 31, 2024 -2,548.06%
Dec 31, 2023 -4,656.49%
Sep 30, 2023 -5,255.13%
Jun 30, 2023 -1,853.33%
Mar 31, 2023 -1,021.99%
Dec 31, 2022 -921.03%
Sep 30, 2022 -898.88%
Jun 30, 2022 -1,967.83%
Mar 31, 2022 -619.40%