Orchestra BioMed Holdings (OBIO) Gross Margin (2022 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Gross Margin came in at 70.91% in Q1 2026, down 2402.0% year-on-year from 3.08% in Q1 2025, and down 28.97% on a QoQ basis from 99.84% in Q4 2025.

Orchestra BioMed Holdings (OBIO) Gross Margin (2022 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 5 years of Gross Margin data on file, last reported at 70.91% in Q1 2026.

  • On a quarterly basis, Gross Margin fell 2402.0% year-over-year to 70.91% in Q1 2026; TTM through Mar 2026 was 99.46%, a 687.0% increase from a year earlier, with the FY2025 full-year figure at 99.43%, up 717.0% from the prior year.
  • Gross Margin for Q1 2026 stood at 70.91%, down from 99.84% in the prior quarter.
  • Over the last five years, Gross Margin for OBIO reached as high as 99.84% in Q4 2025 and fell as low as 70.91% in Q1 2026.
  • Historically, Gross Margin has averaged 90.98% across 5 years, with a median of 94.34% in 2024.
  • Across the five-year window, Gross Margin surged 2276 bps in 2025 and sank 2402 bps in 2026, its largest moves.
  • Year by year, Gross Margin stood at 95.19% in 2022, then decreased by 14 bps to 82.06% in 2023, then declined by 6 bps to 77.08% in 2024, then rose by 30 bps to 99.84% in 2025, then fell by 29 bps to 70.91% in 2026.
  • Per Business Quant data, the three most recent Gross Margin figures were 70.91% in Q1 2026, 99.84% in Q4 2025, and 94.31% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 88.95%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 86.85%
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 91.79%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 90.68%
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Orchestra BioMed Holdings 235.83 Mn 141.43 Mn 78,000.00 70.91%

Historic Data

Download Data
DateValue
Mar 31, 2026 70.91%
Dec 31, 2025 99.84%
Sep 30, 2025 94.31%
Jun 30, 2025 94.50%
Mar 31, 2025 94.93%
Dec 31, 2024 77.08%
Sep 30, 2024 93.11%
Jun 30, 2024 94.34%
Mar 31, 2024 94.52%
Dec 31, 2023 82.06%
Sep 30, 2023 90.21%
Jun 30, 2023 94.10%
Mar 31, 2023 96.22%
Dec 31, 2022 95.19%
Sep 30, 2022 95.18%
Jun 30, 2022 85.04%
Mar 31, 2022 95.15%