Orchestra BioMed Holdings (OBIO) Gross Margin (2022 - 2026)
Orchestra BioMed Holdings' (OBIO) quarterly Gross Margin came in at 70.91% in Q1 2026, down 2402.0% year-on-year from 3.08% in Q1 2025, and down 28.97% on a QoQ basis from 99.84% in Q4 2025.
Orchestra BioMed Holdings (OBIO) Gross Margin (2022 - 2026) Analysis & Trends
Orchestra BioMed Holdings (OBIO) has 5 years of Gross Margin data on file, last reported at 70.91% in Q1 2026.
- On a quarterly basis, Gross Margin fell 2402.0% year-over-year to 70.91% in Q1 2026; TTM through Mar 2026 was 99.46%, a 687.0% increase from a year earlier, with the FY2025 full-year figure at 99.43%, up 717.0% from the prior year.
- Gross Margin for Q1 2026 stood at 70.91%, down from 99.84% in the prior quarter.
- Over the last five years, Gross Margin for OBIO reached as high as 99.84% in Q4 2025 and fell as low as 70.91% in Q1 2026.
- Historically, Gross Margin has averaged 90.98% across 5 years, with a median of 94.34% in 2024.
- Across the five-year window, Gross Margin surged 2276 bps in 2025 and sank 2402 bps in 2026, its largest moves.
- Year by year, Gross Margin stood at 95.19% in 2022, then decreased by 14 bps to 82.06% in 2023, then declined by 6 bps to 77.08% in 2024, then rose by 30 bps to 99.84% in 2025, then fell by 29 bps to 70.91% in 2026.
- Per Business Quant data, the three most recent Gross Margin figures were 70.91% in Q1 2026, 99.84% in Q4 2025, and 94.31% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 88.95% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 86.85% |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 91.79% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 90.68% |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Orchestra BioMed Holdings | 235.83 Mn | 141.43 Mn | 78,000.00 | 70.91% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 70.91% |
| Dec 31, 2025 | 99.84% |
| Sep 30, 2025 | 94.31% |
| Jun 30, 2025 | 94.50% |
| Mar 31, 2025 | 94.93% |
| Dec 31, 2024 | 77.08% |
| Sep 30, 2024 | 93.11% |
| Jun 30, 2024 | 94.34% |
| Mar 31, 2024 | 94.52% |
| Dec 31, 2023 | 82.06% |
| Sep 30, 2023 | 90.21% |
| Jun 30, 2023 | 94.10% |
| Mar 31, 2023 | 96.22% |
| Dec 31, 2022 | 95.19% |
| Sep 30, 2022 | 95.18% |
| Jun 30, 2022 | 85.04% |
| Mar 31, 2022 | 95.15% |