Orchestra BioMed Holdings OBIO
NASDAQ OBIO
$5.08 +0.34 (+7.17%)
At close: Sep 4, 2026 · 4:00 PM EDT

Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Enterprise Value of -$84.6 million for Q1 2026, down 69.65% year-over-year from -$278.8 million in Q1 2025, and up 42.28% quarter-over-quarter from -$146.6 million in Q4 2025.

Analysis

Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Enterprise Value for 7 consecutive years, with -$84.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Enterprise Value fell 69.65% year-over-year to -$84.6 million; the TTM figure through Mar 2026 stood at -$84.6 million (down 69.65% YoY), while the FY2025 annual figure was -$146.6 million, down 44.67% from the prior year.
  • Enterprise Value improved to -$84.6 million in Q1 2026 per OBIO's latest filing, from -$146.6 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$735217.0 in Q3 2022 and bottomed at -$215.9 million in Q2 2023.
  • Historically, Enterprise Value has averaged -$73.4 million across 5 years, with a median of -$84.6 million in 2026.
  • Annual changes were most pronounced in 2023 — Enterprise Value plunged 16418.84% — and 2024, when it surged 81.64%.
  • Orchestra BioMed Holdings' Enterprise Value stood at -$19.9 million in 2022, then slumped by 340.5% to -$87.5 million in 2023, then retreated by 15.79% to -$101.4 million in 2024, then sank by 44.67% to -$146.6 million in 2025, then soared by 42.28% to -$84.6 million in 2026.
  • Business Quant data shows OBIO's Enterprise Value at -$84.6 million in Q1 2026, -$146.6 million in Q4 2025, and -$95.8 million in Q3 2025.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn -
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn
10 Orchestra BioMed Holdings 322.25 Mn 127.72 Mn 63,000.00
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 75.22 Mn
Mar 31, 2026 116.03 Mn
Dec 31, 2025 90.06 Mn
Sep 30, 2025 12.27 Mn
Jun 30, 2025 64.07 Mn
Mar 31, 2025 92.25 Mn
Dec 31, 2024 51.43 Mn
Sep 30, 2024 99.15 Mn
Jun 30, 2024 196.57 Mn
Mar 31, 2024 79.19 Mn
Dec 31, 2023 185.05 Mn
Sep 30, 2023 118.89 Mn
Jun 30, 2023 34.35 Mn
Mar 31, 2023 386.16 Mn
Dec 31, 2022 17.45 Mn
Sep 30, 2022 135.12 Mn
Jun 30, 2022 202.38 Mn
Mar 31, 2022 201.24 Mn
Dec 31, 2021 204.38 Mn
Sep 30, 2021 200.47 Mn