Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Enterprise Value came in at -$84.6 million in Q1 2026, down 69.65% year-on-year from -$278.8 million in Q1 2025, and up 42.28% on a QoQ basis from -$146.6 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 7 years of Enterprise Value data on file, last reported at -$84.6 million in Q1 2026.

  • On a quarterly basis, Enterprise Value fell 69.65% year-over-year to -$84.6 million in Q1 2026; TTM through Mar 2026 was -$84.6 million, a 69.65% decrease from a year earlier, with the FY2025 full-year figure at -$146.6 million, down 44.67% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$84.6 million, up from -$146.6 million in the prior quarter.
  • Over the last five years, Enterprise Value for OBIO reached as high as -$735217.0 in Q3 2022 and fell as low as -$215.9 million in Q2 2023.
  • Historically, Enterprise Value has averaged -$73.4 million across 5 years, with a median of -$84.6 million in 2026.
  • Across the five-year window, Enterprise Value slumped 16418.84% in 2023 and soared 81.64% in 2024, its largest moves.
  • Year by year, Enterprise Value stood at -$19.9 million in 2022, then slumped by 340.5% to -$87.5 million in 2023, then slipped by 15.79% to -$101.4 million in 2024, then sank by 44.67% to -$146.6 million in 2025, then surged by 42.28% to -$84.6 million in 2026.
  • Per Business Quant data, the three most recent Enterprise Value figures were -$84.6 million in Q1 2026, -$146.6 million in Q4 2025, and -$95.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Orchestra BioMed Holdings 228.31 Mn 143.68 Mn 78,000.00 -84.63 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -84.63 Mn
Dec 31, 2025 -146.63 Mn
Sep 30, 2025 -95.82 Mn
Jun 30, 2025 -33.92 Mn
Mar 31, 2025 -49.88 Mn
Dec 31, 2024 -101.35 Mn
Sep 30, 2024 -95.87 Mn
Jun 30, 2024 -53.93 Mn
Mar 31, 2024 -23.35 Mn
Dec 31, 2023 -87.53 Mn
Sep 30, 2023 -108.49 Mn
Jun 30, 2023 -215.85 Mn
Mar 31, 2023 -127.13 Mn
Dec 31, 2022 -19.87 Mn
Sep 30, 2022 -735,217.00
Jun 30, 2022 -1.31 Mn
Mar 31, 2022 -1.42 Mn
Dec 31, 2021 -1.75 Mn
Sep 30, 2021 -1.78 Mn
Jun 30, 2021 -1.91 Mn