Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Enterprise Value of -$84.6 million for Q1 2026, down 69.65% year-over-year from -$278.8 million in Q1 2025, and up 42.28% quarter-over-quarter from -$146.6 million in Q4 2025.

Orchestra BioMed Holdings (OBIO) Enterprise Value (2020 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Enterprise Value for 7 consecutive years, with -$84.6 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Enterprise Value fell 69.65% year-over-year to -$84.6 million; the TTM figure through Mar 2026 stood at -$84.6 million (down 69.65% YoY), while the FY2025 annual figure was -$146.6 million, down 44.67% from the prior year.
  • Enterprise Value improved to -$84.6 million in Q1 2026 per OBIO's latest filing, from -$146.6 million in the prior quarter.
  • Across five years, Enterprise Value topped out at -$735217.0 in Q3 2022 and bottomed at -$215.9 million in Q2 2023.
  • Historically, Enterprise Value has averaged -$73.4 million across 5 years, with a median of -$84.6 million in 2026.
  • Annual changes were most pronounced in 2023 — Enterprise Value plunged 16418.84% — and 2024, when it surged 81.64%.
  • Orchestra BioMed Holdings' Enterprise Value stood at -$19.9 million in 2022, then slumped by 340.5% to -$87.5 million in 2023, then retreated by 15.79% to -$101.4 million in 2024, then sank by 44.67% to -$146.6 million in 2025, then soared by 42.28% to -$84.6 million in 2026.
  • Business Quant data shows OBIO's Enterprise Value at -$84.6 million in Q1 2026, -$146.6 million in Q4 2025, and -$95.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Orchestra BioMed Holdings 265.06 Mn 80.63 Mn 63,000.00 -184.43 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -184.43 Mn
Mar 31, 2026 -84.63 Mn
Dec 31, 2025 -146.63 Mn
Sep 30, 2025 -95.82 Mn
Jun 30, 2025 -33.92 Mn
Mar 31, 2025 -49.88 Mn
Dec 31, 2024 -101.35 Mn
Sep 30, 2024 -95.87 Mn
Jun 30, 2024 -53.93 Mn
Mar 31, 2024 -23.35 Mn
Dec 31, 2023 -87.53 Mn
Sep 30, 2023 -108.49 Mn
Jun 30, 2023 -215.85 Mn
Mar 31, 2023 -127.13 Mn
Dec 31, 2022 -19.87 Mn
Sep 30, 2022 -735,217.00
Jun 30, 2022 -1.31 Mn
Mar 31, 2022 -1.42 Mn
Dec 31, 2021 -1.75 Mn
Sep 30, 2021 -1.78 Mn