Orchestra BioMed Holdings (OBIO) EBITDA Margin (2022 - 2026)
Orchestra BioMed Holdings (OBIO) recorded EBITDA Margin of -25295.45% in Q2 2026, down 22993.30 percentage points from -2302.15% a year earlier and down 5308.18 percentage points from the prior quarter.
Orchestra BioMed Holdings (OBIO) EBITDA Margin (2022 - 2026) Analysis & Trends
On a TTM basis, Orchestra BioMed Holdings' EBITDA Margin came in at -180.27% as of Jun 30, 2026, up 2229.48 percentage points year-over-year; for FY2025, it came in at -153.75%, up 2272.06 percentage points from FY2024.
- Annual EBITDA Margin has a three-year change of +764.30 percentage points (FY2022 to FY2025).
- Across earlier years, EBITDA Margin came in at -2425.82% in FY2024 (-570.05 pp), -1855.76% in FY2023 (-937.70 pp) and -918.06% in FY2022.
- The Q2 2026 figure is the lowest quarterly EBITDA Margin in data going back to Q1 2022.
- On a year-over-year basis, EBITDA Margin rose in three of the last eight quarters, with an average year-over-year change of -4369.12 percentage points.
- Peak year-over-year performance for EBITDA Margin in the last five years was a gain of 6580.61 percentage points in Q4 2025, against a drop of 22993.30 percentage points in Q2 2026 at the low end.
- Per Business Quant, the preceding three quarters came in at -19987.27% (Q1 2026), 22.11% (Q4 2025) and -2349.83% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Thermo Fisher Scientific | 251.30 Bn | 230.45 Bn | 4.88 Bn | 24.20% |
| 2 | Abbott Laboratories | 174.70 Bn | 145.78 Bn | 7.27 Bn | 21.86% |
| 3 | Danaher | 158.94 Bn | 142.76 Bn | 3.61 Bn | 28.51% |
| 4 | Intuitive Surgical | 145.87 Bn | 125.42 Bn | 1.96 Bn | 41.08% |
| 5 | Medtronic | 111.49 Bn | 77.36 Bn | 6.34 Bn | 25.55% |
| 6 | Stryker | 106.96 Bn | 93.08 Bn | 4.50 Bn | 29.67% |
| 7 | Boston Scientific | 63.62 Bn | 58.63 Bn | 3.85 Bn | 28.17% |
| 8 | Edwards Lifesciences | 50.80 Bn | 34.92 Bn | 1.35 Bn | 31.93% |
| 9 | Becton Dickinson | 49.59 Bn | 46.74 Bn | 2.32 Bn | 24.62% |
| 10 | Orchestra BioMed Holdings | 365.44 Mn | -31.16 Mn | 63,000.00 | -25,295.45% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -25,295.45% |
| Mar 31, 2026 | -19,987.27% |
| Dec 31, 2025 | 22.11% |
| Sep 30, 2025 | -2,349.83% |
| Jun 30, 2025 | -2,302.15% |
| Mar 31, 2025 | -2,170.28% |
| Dec 31, 2024 | -6,558.50% |
| Sep 30, 2024 | -1,648.02% |
| Jun 30, 2024 | -2,157.46% |
| Mar 31, 2024 | -2,314.35% |
| Dec 31, 2023 | -4,736.26% |
| Sep 30, 2023 | -3,449.40% |
| Jun 30, 2023 | -1,407.98% |
| Mar 31, 2023 | -985.74% |
| Dec 31, 2022 | -884.68% |
| Sep 30, 2022 | -860.96% |
| Jun 30, 2022 | -1,891.27% |
| Mar 31, 2022 | -586.61% |
Orchestra BioMed Holdings EBITDA Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=ebitda-margin&ticker=OBIO&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "ebitda-margin", "ticker": "OBIO", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=ebitda-margin&ticker=OBIO&period=max&api_key=YOUR_API_KEY");
const data = await res.json();