Orchestra BioMed Holdings (OBIO) EBIT Margin (2022 - 2026)

Orchestra BioMed Holdings (OBIO) reported EBIT Margin of 20069.09% for Q1 2026, down 1788925.0% year-over-year from N/an in Q1 2025, and down 91967.94% on a QoQ basis from 21.85% in Q4 2025.

Orchestra BioMed Holdings (OBIO) has 5 years of EBIT Margin data on file, last reported at 20069.09% in Q1 2026.

  • Quarterly EBIT Margin fell 1788925.0% year-over-year to 20069.09% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 167.96% (up 221593.0% YoY) and the FY2025 annual result came in at 154.73%, up 228276.0% from the prior year.
  • EBIT Margin declined to 20069.09% in Q1 2026 per OBIO's latest filing, from 21.85% in the prior quarter.
  • Across five years, EBIT Margin topped out at 21.85% in Q4 2025 and bottomed at 20069.09% in Q1 2026.
  • The 5-year median for EBIT Margin is 2166.97% (2024), against an average of 3207.6%.
  • The widest annual swing landed in 2025, when EBIT Margin surged 661355 bps; it then plunged 1788925 bps in 2026.
  • Tracing OBIO's EBIT Margin over 5 years: stood at 891.02% in 2022, then sank by 435 bps to 4763.74% in 2023, then plunged by 38 bps to 6591.7% in 2024, then surged by 100 bps to 21.85% in 2025, then sank by 91968 bps to 20069.09% in 2026.
  • Per Business Quant, the three latest OBIO EBIT Margin figures stand at 20069.09% (Q1 2026), 21.85% (Q4 2025), and 2359.23% (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 17.83%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 23.02%
10 Orchestra BioMed Holdings 245.24 Mn 255.02 Mn 78,000.00 -20,069.09%

Historic Data

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DateValue
Mar 31, 2026 -20,069.09%
Dec 31, 2025 21.85%
Sep 30, 2025 -2,359.23%
Jun 30, 2025 -2,311.84%
Mar 31, 2025 -2,179.84%
Dec 31, 2024 -6,591.70%
Sep 30, 2024 -1,655.72%
Jun 30, 2024 -2,166.97%
Mar 31, 2024 -2,326.29%
Dec 31, 2023 -4,763.74%
Sep 30, 2023 -3,466.35%
Jun 30, 2023 -1,415.96%
Mar 31, 2023 -991.84%
Dec 31, 2022 -891.02%
Sep 30, 2022 -865.61%
Jun 30, 2022 -1,903.74%
Mar 31, 2022 -592.15%