Neurogene (NGNE) Operating Income (2017 - 2026)

Neurogene (NGNE) reported Operating Income of -$33.3 million for Q1 2026, down 28.67% on a YoY basis from -$46.8 million in Q1 2025, and down 21.14% quarter-over-quarter from -$27.5 million in Q4 2025.

Neurogene (NGNE) Operating Income (2017 - 2026) Analysis & Trends

Neurogene has reported Operating Income for 10 years, with the latest figure at -$33.3 million in Q1 2026.

  • For the quarter ending Q1 2026, Operating Income fell 28.67% year-over-year to -$33.3 million; the trailing twelve-month figure through Mar 2026 stood at -$110.8 million (down 23.41% YoY), and the FY2025 full-year result was -$103.3 million, down 25.09% from the prior year.
  • Operating Income for Q1 2026 stood at -$33.3 million, down from -$27.5 million in the prior quarter.
  • The five-year high for Operating Income was -$11.7 million in Q4 2022, with the low at -$33.3 million in Q1 2026.
  • Historically, Operating Income has averaged -$19.5 million across 5 years, with a median of -$18.8 million in 2024.
  • Annual changes were most pronounced in 2022 — Operating Income climbed 23.09% — and 2024, when it tumbled 59.84%.
  • Neurogene's Operating Income stood at -$11.7 million in 2022, then dropped by 26.24% to -$14.7 million in 2023, then sank by 46.01% to -$21.5 million in 2024, then declined by 27.97% to -$27.5 million in 2025, then dropped by 21.14% to -$33.3 million in 2026.
  • The last three Operating Income figures came in at -$33.3 million (Q1 2026), -$27.5 million (Q4 2025), and -$23.8 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Op. Inc (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -32.68 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.97 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -15.76 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Neurogene 216.17 Mn 216.17 Mn - -33.35 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -33.35 Mn
Dec 31, 2025 -27.53 Mn
Sep 30, 2025 -23.80 Mn
Jun 30, 2025 -26.08 Mn
Mar 31, 2025 -25.92 Mn
Dec 31, 2024 -21.51 Mn
Sep 30, 2024 -22.18 Mn
Jun 30, 2024 -20.13 Mn
Mar 31, 2024 -18.78 Mn
Dec 31, 2023 -14.73 Mn
Sep 30, 2023 -15.22 Mn
Jun 30, 2023 -12.60 Mn
Mar 31, 2023 -13.04 Mn
Dec 31, 2022 -11.67 Mn
Sep 30, 2022 -13.61 Mn
Jun 30, 2022 -15.87 Mn
Mar 31, 2022 -15.37 Mn
Dec 31, 2021 -15.17 Mn
Sep 30, 2021 -15.45 Mn
Jun 30, 2021 -15.12 Mn