Nautilus Biotechnology (NAUT) Operating Expenses (2020 - 2026)

Nautilus Biotechnology's (NAUT) quarterly Operating Expenses came in at $16.1 million in Q1 2026, down 14.43% year-on-year from $18.8 million in Q1 2025, and up 4.54% quarter-over-quarter from $15.4 million in Q4 2025.

Nautilus Biotechnology (NAUT) Operating Expenses (2020 - 2026) Analysis & Trends

Nautilus Biotechnology has disclosed Operating Expenses across 7 years of filings, most recently posting $16.1 million for Q1 2026.

  • Operating Expenses for Q1 2026 came in at $16.1 million, down 14.43% year-over-year; the trailing twelve-month figure through Mar 2026 was $64.1 million (down 18.54% YoY), and the FY2025 annual result was $66.8 million, down 17.97% from the prior year.
  • Operating Expenses came in at $16.1 million for Q1 2026 at Nautilus Biotechnology, up from $15.4 million in the prior quarter.
  • In the past five years, Operating Expenses ranged from a high of $21.6 million in Q1 2024 to a low of $15.4 million in Q4 2025.
  • The 5-year median for Operating Expenses is $18.1 million (2023), against an average of $17.9 million.
  • Across the five-year window, Operating Expenses surged 90.35% in 2022 and decreased 22.8% in 2025, its largest moves.
  • Nautilus Biotechnology's Operating Expenses stood at $16.3 million in 2022, then grew by 22.68% to $20.0 million in 2023, then decreased by 0.1% to $20.0 million in 2024, then fell by 22.8% to $15.4 million in 2025, then increased by 4.54% to $16.1 million in 2026.
  • The last three Operating Expenses figures came in at $16.1 million (Q1 2026), $15.4 million (Q4 2025), and $15.5 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Opex (Qtr)
1 Alterity Therapeutics 762,369.55 Bn 762,369.51 Bn - 4.33 Mn
2 Belite Bio 55,096.00 Bn 55,096.00 Bn - 32.68 Mn
3 Quantum Biopharma 17,755.80 Bn 17,755.79 Bn - 2.97 Mn
4 Legend Biotech 3,486.00 Bn 3,485.71 Bn 242.10 Mn -138.30 Mn
5 Akari Therapeutics 1,737.42 Bn 1,737.41 Bn - 15.76 Mn
6 Evaxion A 1,551.28 Bn 1,551.26 Bn - -3.82 Mn
7 Psyence Biomedical 227.32 Bn 227.31 Bn - 574,669.00
8 Vertex Pharmaceuticals 110.84 Bn 103.59 Bn 2.59 Bn 1.85 Bn
9 Abivax 91.71 Bn 91.71 Bn - -67.40 Mn
10 Nautilus Biotechnology 289.99 Mn 194.12 Mn - 16.12 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 16.12 Mn
Dec 31, 2025 15.42 Mn
Sep 30, 2025 15.47 Mn
Jun 30, 2025 17.10 Mn
Mar 31, 2025 18.84 Mn
Dec 31, 2024 19.98 Mn
Sep 30, 2024 19.10 Mn
Jun 30, 2024 20.79 Mn
Mar 31, 2024 21.61 Mn
Dec 31, 2023 20.00 Mn
Sep 30, 2023 19.08 Mn
Jun 30, 2023 19.02 Mn
Mar 31, 2023 18.06 Mn
Dec 31, 2022 16.30 Mn
Sep 30, 2022 15.82 Mn
Jun 30, 2022 15.47 Mn
Mar 31, 2022 16.02 Mn
Dec 31, 2021 16.82 Mn
Sep 30, 2021 14.57 Mn
Jun 30, 2021 10.70 Mn