Marker Therapeutics (MRKR) Net Margin (2016 - 2025)
Marker Therapeutics (MRKR) reported Net Margin of 780.69% for Q4 2025, up 55475.0% year-over-year from N/an in Q4 2024, and up 581.6% quarter-over-quarter from 162.11% in Q3 2025.
Marker Therapeutics (MRKR) Net Margin (2016 - 2025) Analysis & Trends
Marker Therapeutics (MRKR) has 9 years of Net Margin data on file, last reported at 780.69% in Q4 2025.
- Net Margin for Q4 2025 came in at 780.69%, up 55475.0% year-over-year; the trailing twelve-month figure through Dec 2025 was 65.2% (down 4087.0% YoY), and the FY2025 annual result was 342.96%, down 18014.0% from the prior year.
- Net Margin improved to 780.69% in Q4 2025 per MRKR's latest filing, from 162.11% in the prior quarter.
- Over five years, Net Margin peaked at 780.69% in Q4 2025 and troughed at 1373.6% in Q1 2025.
- A 4-year average of 302.05% and a median of 119.84% in 2024 frame the typical range for Net Margin.
- The sharpest annual moves came in 2024 and 2025: Net Margin jumped 120542 bps in 2024, then sank 118126 bps in 2025.
- A 4-year view of Net Margin shows it stood at 107.1% in 2022, then jumped by 94 bps to 5.96% in 2023, then soared by 3893 bps to 225.94% in 2024, then soared by 246 bps to 780.69% in 2025.
- Business Quant data shows MRKR's Net Margin at 780.69% in Q4 2025, 162.11% in Q3 2025, and 479.92% in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 719,706.53 Bn | 719,706.50 Bn | - | - |
| 2 | Belite Bio | 55,800.00 Bn | 55,800.00 Bn | - | - |
| 3 | Quantum Biopharma | 18,182.30 Bn | 18,182.29 Bn | - | - |
| 4 | Legend Biotech | 3,154.00 Bn | 3,153.71 Bn | 242.10 Mn | 0.82% |
| 5 | Akari Therapeutics | 1,844.30 Bn | 1,844.29 Bn | - | - |
| 6 | Evaxion A | 1,567.96 Bn | 1,567.94 Bn | - | - |
| 7 | Psyence Biomedical | 251.43 Bn | 251.42 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 112.56 Bn | 105.31 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 94.37 Bn | 94.37 Bn | - | - |
| 10 | Marker Therapeutics | 28.20 Mn | 28.20 Mn | - | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | 780.69% |
| Sep 30, 2025 | -162.11% |
| Jun 30, 2025 | -479.92% |
| Mar 31, 2025 | -1,373.60% |
| Dec 31, 2024 | 225.94% |
| Sep 30, 2024 | -119.84% |
| Jun 30, 2024 | -109.63% |
| Mar 31, 2024 | -192.34% |
| Dec 31, 2023 | -5.96% |
| Jun 30, 2023 | -1,315.05% |
| Mar 31, 2023 | -29.71% |
| Dec 31, 2022 | -107.10% |
| Sep 30, 2022 | -119.34% |
| Jun 30, 2022 | -507.45% |
| Mar 31, 2022 | -1,015.39% |
| Jun 30, 2020 | -1,358.59% |
| Dec 31, 2019 | -2,588.58% |
| Jun 30, 2018 | -2,268.90% |
| Sep 30, 2017 | -2,179.30% |
| Jun 30, 2016 | 984.86% |