Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025)

Monopar Therapeutics' (MNPR) quarterly Free Cash Flow came in at -$3.4 million in Q4 2025, down 68.64% year-on-year from -$10.7 million in Q4 2024, and down 61.21% quarter-over-quarter from -$2.1 million in Q3 2025.

Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025) Analysis & Trends

Monopar Therapeutics has disclosed Free Cash Flow across 9 years of filings, most recently posting -$3.4 million for Q4 2025.

  • Free Cash Flow for Q4 2025 came in at -$3.4 million, down 68.64% year-over-year; the trailing twelve-month figure through Dec 2025 was -$12.2 million (down 90.52% YoY), and the FY2025 annual result was -$12.2 million, down 90.52% from the prior year.
  • Free Cash Flow came in at -$3.4 million for Q4 2025 at Monopar Therapeutics, down from -$2.1 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of -$1.1 million in Q3 2024 to a low of -$5.7 million in Q1 2025.
  • The 5-year median for Free Cash Flow is -$1.9 million (2021), against an average of -$2.1 million.
  • Across the five-year window, Free Cash Flow jumped 44.66% in 2024 and plunged 242.11% in 2025, its largest moves.
  • Monopar Therapeutics' Free Cash Flow stood at -$2.0 million in 2021, then surged by 35.93% to -$1.3 million in 2022, then fell by 18.75% to -$1.5 million in 2023, then dropped by 29.27% to -$2.0 million in 2024, then tumbled by 68.64% to -$3.4 million in 2025.
  • The last three Free Cash Flow figures came in at -$3.4 million (Q4 2025), -$2.1 million (Q3 2025), and -$1.1 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -1.67 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -12.20 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -2.49 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn 1.29 Bn
9 Abivax 90.15 Bn 90.15 Bn - 63,220.27
10 Monopar Therapeutics 441.25 Mn 441.25 Mn - -3.37 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.37 Mn
Dec 31, 2025 -3.37 Mn
Sep 30, 2025 -2.09 Mn
Sep 30, 2025 -2.09 Mn
Jun 30, 2025 -1.08 Mn
Jun 30, 2025 -1.08 Mn
Mar 31, 2025 -5.66 Mn
Mar 31, 2025 -5.66 Mn
Dec 31, 2024 -2.00 Mn
Dec 31, 2024 -2.00 Mn
Sep 30, 2024 -1.07 Mn
Sep 30, 2024 -1.07 Mn
Jun 30, 2024 -1.68 Mn
Jun 30, 2024 -1.68 Mn
Mar 31, 2024 -1.66 Mn
Mar 31, 2024 -1.66 Mn
Dec 31, 2023 -1.55 Mn
Dec 31, 2023 -1.55 Mn
Sep 30, 2023 -1.94 Mn
Sep 30, 2023 -1.94 Mn