Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025)

Monopar Therapeutics (MNPR) reported Free Cash Flow of -$3.4 million for Q4 2025, down 68.64% on a YoY basis from -$10.7 million in Q4 2024, and down 61.21% sequentially from -$2.1 million in Q3 2025.

Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025) Analysis & Trends

Monopar Therapeutics (MNPR) has 9 years of Free Cash Flow data on file, last reported at -$3.4 million in Q4 2025.

  • For the quarter ending Q4 2025, Free Cash Flow fell 68.64% year-over-year to -$3.4 million; the trailing twelve-month figure through Dec 2025 stood at -$12.2 million (down 90.52% YoY), and the FY2025 full-year result was -$12.2 million, down 90.52% from the prior year.
  • Free Cash Flow retreated to -$3.4 million in Q4 2025, from -$2.1 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of -$1.1 million in Q3 2024 to a low of -$5.7 million in Q1 2025.
  • A 5-year average of -$2.1 million and a median of -$1.9 million in 2021 frame the typical range for Free Cash Flow.
  • Across the five-year window, Free Cash Flow jumped 44.66% in 2024 and slumped 242.11% in 2025, its largest moves.
  • Tracing MNPR's Free Cash Flow over 5 years: stood at -$2.0 million in 2021, then jumped by 35.93% to -$1.3 million in 2022, then declined by 18.75% to -$1.5 million in 2023, then slipped by 29.27% to -$2.0 million in 2024, then plunged by 68.64% to -$3.4 million in 2025.
  • Business Quant data shows MNPR's Free Cash Flow at -$3.4 million in Q4 2025, -$2.1 million in Q3 2025, and -$1.1 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Monopar Therapeutics 707.36 Mn 645.53 Mn - -3.37 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.37 Mn
Dec 31, 2025 -3.37 Mn
Sep 30, 2025 -2.09 Mn
Sep 30, 2025 -2.09 Mn
Jun 30, 2025 -1.08 Mn
Jun 30, 2025 -1.08 Mn
Mar 31, 2025 -5.66 Mn
Mar 31, 2025 -5.66 Mn
Dec 31, 2024 -2.00 Mn
Dec 31, 2024 -2.00 Mn
Sep 30, 2024 -1.07 Mn
Sep 30, 2024 -1.07 Mn
Jun 30, 2024 -1.68 Mn
Jun 30, 2024 -1.68 Mn
Mar 31, 2024 -1.66 Mn
Mar 31, 2024 -1.66 Mn
Dec 31, 2023 -1.55 Mn
Dec 31, 2023 -1.55 Mn
Sep 30, 2023 -1.94 Mn
Sep 30, 2023 -1.94 Mn