Monopar Therapeutics MNPR
NASDAQ MNPR
$117.56 -0.99 (-0.84%)
At close: Sep 4, 2026 · 4:00 PM EDT

Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025)

Monopar Therapeutics (MNPR) posted Free Cash Flow of -$3.4 million for Q4 2025, down 61.21% sequentially from -$2.1 million in Q3 2025, and down 68.64% YoY from -$10.7 million in Q4 2024.

Analysis

Monopar Therapeutics (MNPR) Free Cash Flow (2017 - 2025) Analysis & Trends

Monopar Therapeutics has reported Free Cash Flow for 9 years, with the latest figure at -$3.4 million in Q4 2025.

  • Quarterly Free Cash Flow fell 68.64% year-over-year to -$3.4 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$12.2 million (down 90.52% YoY) and the FY2025 annual result came in at -$12.2 million, down 90.52% from the prior year.
  • Free Cash Flow retreated to -$3.4 million in Q4 2025 per MNPR's latest filing, from -$2.1 million in the prior quarter.
  • Over five years, Free Cash Flow peaked at -$1.1 million in Q3 2024 and troughed at -$5.7 million in Q1 2025.
  • A 5-year average of -$2.1 million and a median of -$1.9 million in 2021 frame the typical range for Free Cash Flow.
  • The sharpest annual moves came in 2024 and 2025: Free Cash Flow soared 44.66% in 2024, then plunged 242.11% in 2025.
  • Over 5 years, Free Cash Flow stood at -$2.0 million in 2021, then jumped by 35.93% to -$1.3 million in 2022, then decreased by 18.75% to -$1.5 million in 2023, then fell by 29.27% to -$2.0 million in 2024, then tumbled by 68.64% to -$3.4 million in 2025.
  • According to Business Quant data, Free Cash Flow over the past three periods registered -$3.4 million, -$2.1 million, and -$1.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn -
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -563.00 Mn
5 Revolution Medicines 44.33 Bn 44.33 Bn - -389.61 Mn
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 437.80 Mn
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 292.04 Mn
8 Royalty Pharma 28.45 Bn 27.61 Bn - 477.44 Mn
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -95.09 Mn
10 Monopar Therapeutics 1.01 Bn 954.06 Mn - -
Historic Data

Historic Data

Download Data
DateValue
Dec 31, 2025 -3.37 Mn
Sep 30, 2025 -2.09 Mn
Jun 30, 2025 -1.08 Mn
Mar 31, 2025 -5.66 Mn
Dec 31, 2024 -2.00 Mn
Sep 30, 2024 -1.07 Mn
Jun 30, 2024 -1.68 Mn
Mar 31, 2024 -1.66 Mn
Dec 31, 2023 -1.55 Mn
Sep 30, 2023 -1.94 Mn
Jun 30, 2023 -2.10 Mn
Mar 31, 2023 -2.27 Mn
Dec 31, 2022 -1.30 Mn
Sep 30, 2022 -2.15 Mn
Jun 30, 2022 -1.31 Mn
Mar 31, 2022 -2.47 Mn
Dec 31, 2021 -2.03 Mn
Sep 30, 2021 -1.94 Mn
Jun 30, 2021 -1.41 Mn
Mar 31, 2021 -1.94 Mn