Monopar Therapeutics (MNPR) Enterprise Value (2016 - 2025)

Monopar Therapeutics (MNPR) reported Enterprise Value of -$61.8 million for Q4 2025, down 34.96% on a YoY basis from -$95.1 million in Q4 2024, and up 51.57% sequentially from -$127.7 million in Q3 2025.

Monopar Therapeutics (MNPR) Enterprise Value (2016 - 2025) Analysis & Trends

Monopar Therapeutics (MNPR) has 10 years of Enterprise Value data on file, last reported at -$61.8 million in Q4 2025.

  • For the quarter ending Q4 2025, Enterprise Value fell 34.96% year-over-year to -$61.8 million; the trailing twelve-month figure through Dec 2025 stood at -$61.8 million (down 34.96% YoY), and the FY2025 full-year result was -$61.8 million, down 34.96% from the prior year.
  • Enterprise Value improved to -$61.8 million in Q4 2025, from -$127.7 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$5.5 million in Q3 2023 to a low of -$127.7 million in Q3 2025.
  • A 5-year average of -$25.7 million and a median of -$17.1 million in 2022 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value jumped 60.39% in 2023 and tumbled 2020.86% in 2025, its largest moves.
  • Tracing MNPR's Enterprise Value over 5 years: stood at -$20.0 million in 2021, then soared by 59.1% to -$8.2 million in 2022, then advanced by 11.24% to -$7.3 million in 2023, then tumbled by 530.55% to -$45.8 million in 2024, then sank by 34.96% to -$61.8 million in 2025.
  • Business Quant data shows MNPR's Enterprise Value at -$61.8 million in Q4 2025, -$127.7 million in Q3 2025, and -$39.5 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -283.54 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -61.40 Mn
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -2.83 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn -4.79 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -1.91 Bn
10 Monopar Therapeutics 800.03 Mn 738.20 Mn - -61.83 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -61.83 Mn
Sep 30, 2025 -127.68 Mn
Jun 30, 2025 -39.50 Mn
Mar 31, 2025 -39.71 Mn
Dec 31, 2024 -45.82 Mn
Sep 30, 2024 -6.02 Mn
Jun 30, 2024 -6.12 Mn
Mar 31, 2024 -7.81 Mn
Dec 31, 2023 -7.27 Mn
Sep 30, 2023 -5.52 Mn
Jun 30, 2023 -7.21 Mn
Mar 31, 2023 -10.42 Mn
Dec 31, 2022 -8.19 Mn
Sep 30, 2022 -13.92 Mn
Jun 30, 2022 -16.46 Mn
Mar 31, 2022 -17.82 Mn
Dec 31, 2021 -20.01 Mn
Sep 30, 2021 -21.98 Mn
Jun 30, 2021 -24.29 Mn
Mar 31, 2021 -25.72 Mn