Monopar Therapeutics (MNPR) Enterprise Value (2016 - 2025)

Monopar Therapeutics' (MNPR) quarterly Enterprise Value came in at -$61.8 million in Q4 2025, down 34.96% year-on-year from -$95.1 million in Q4 2024, and up 51.57% quarter-over-quarter from -$127.7 million in Q3 2025.

Monopar Therapeutics (MNPR) Enterprise Value (2016 - 2025) Analysis & Trends

Monopar Therapeutics has disclosed Enterprise Value across 10 years of filings, most recently posting -$61.8 million for Q4 2025.

  • Enterprise Value for Q4 2025 came in at -$61.8 million, down 34.96% year-over-year; the trailing twelve-month figure through Dec 2025 was -$61.8 million (down 34.96% YoY), and the FY2025 annual result was -$61.8 million, down 34.96% from the prior year.
  • Enterprise Value came in at -$61.8 million for Q4 2025 at Monopar Therapeutics, up from -$127.7 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$5.5 million in Q3 2023 to a low of -$127.7 million in Q3 2025.
  • The 5-year median for Enterprise Value is -$17.1 million (2022), against an average of -$25.4 million.
  • Across the five-year window, Enterprise Value jumped 67.87% in 2023 and sank 2020.86% in 2025, its largest moves.
  • Monopar Therapeutics' Enterprise Value stood at -$20.0 million in 2021, then jumped by 59.1% to -$8.2 million in 2022, then climbed by 11.24% to -$7.3 million in 2023, then slumped by 530.55% to -$45.8 million in 2024, then plunged by 34.96% to -$61.8 million in 2025.
  • The last three Enterprise Value figures came in at -$61.8 million (Q4 2025), -$127.7 million (Q3 2025), and -$39.5 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 814,307.08 Bn 814,307.05 Bn - -32.30 Mn
2 Belite Bio 55,320.00 Bn 55,320.00 Bn - -
3 Quantum Biopharma 17,149.72 Bn 17,149.72 Bn - -4.14 Mn
4 Legend Biotech 3,590.00 Bn 3,589.71 Bn 242.10 Mn -286.70 Mn
5 Akari Therapeutics 1,650.72 Bn 1,650.72 Bn - -2.77 Mn
6 Evaxion A 1,522.09 Bn 1,522.07 Bn - -18.44 Mn
7 Psyence Biomedical 229.39 Bn 229.38 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 113.09 Bn 105.85 Bn 2.59 Bn -7.25 Bn
9 Abivax 90.15 Bn 90.15 Bn - -584.73 Mn
10 Monopar Therapeutics 441.25 Mn 441.25 Mn - -61.83 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -61.83 Mn
Sep 30, 2025 -127.68 Mn
Jun 30, 2025 -39.50 Mn
Mar 31, 2025 -39.71 Mn
Dec 31, 2024 -45.82 Mn
Sep 30, 2024 -6.02 Mn
Jun 30, 2024 -6.12 Mn
Mar 31, 2024 -7.81 Mn
Dec 31, 2023 -7.27 Mn
Sep 30, 2023 -5.52 Mn
Jun 30, 2023 -7.21 Mn
Mar 31, 2023 -5.73 Mn
Dec 31, 2022 -8.19 Mn
Sep 30, 2022 -13.92 Mn
Jun 30, 2022 -16.46 Mn
Mar 31, 2022 -17.82 Mn
Dec 31, 2021 -20.01 Mn
Sep 30, 2021 -22.34 Mn
Jun 30, 2021 -23.84 Mn
Mar 31, 2021 -25.72 Mn