Monopar Therapeutics (MNPR) Change in Cash (2017 - 2025)

Quarterly results put Change in Cash at -$65.8 million for Q4 2025, down 265.45% from a year ago — trailing twelve months through Dec 2025 was $16.0 million (down 58.45% YoY), and the annual figure for FY2025 was $16.0 million, down 58.45%.

Monopar Therapeutics has reported Change in Cash over the past 9 years, most recently at -$65.8 million for Q4 2025.

  • Change in Cash reached -$65.8 million in Q4 2025 per MNPR's latest filing, down from $88.2 million in the prior quarter.
  • Across five years, Change in Cash topped out at $88.2 million in Q3 2025 and bottomed at -$65.8 million in Q4 2025.
  • Median Change in Cash over the past 5 years was -$1.6 million (2021), compared with a mean of $2.3 million.
  • The largest annual shift saw Change in Cash crashed 2997.62% in 2021 before it surged 88410.54% in 2025.
  • Over 5 years, Change in Cash stood at -$2.0 million in 2021, then tumbled by 200.84% to -$6.1 million in 2022, then skyrocketed by 128.56% to $1.8 million in 2023, then skyrocketed by 2173.12% to $39.8 million in 2024, then tumbled by 265.45% to -$65.8 million in 2025.
  • Business Quant data shows Change in Cash for MNPR at -$65.8 million in Q4 2025, $88.2 million in Q3 2025, and -$209473.0 in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.44 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 417.10 Mn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -153.10 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 53.61 Mn
10 Monopar Therapeutics 466.82 Mn 466.82 Mn - -65.84 Mn

Historic Data

Download Data 🔒
DateValue
Dec 31, 2025 -65.84 Mn
Sep 30, 2025 88.18 Mn
Jun 30, 2025 -209,473.00
Mar 31, 2025 -6.10 Mn
Dec 31, 2024 39.80 Mn
Sep 30, 2024 -99,847.00
Jun 30, 2024 -1.69 Mn
Mar 31, 2024 541,499.00
Dec 31, 2023 1.75 Mn
Sep 30, 2023 -1.70 Mn
Jun 30, 2023 1.49 Mn
Mar 31, 2023 -2.46 Mn
Dec 31, 2022 -6.13 Mn
Sep 30, 2022 -2.15 Mn
Jun 30, 2022 -1.36 Mn
Mar 31, 2022 -2.48 Mn
Dec 31, 2021 -2.04 Mn
Sep 30, 2021 -1.95 Mn
Jun 30, 2021 -1.43 Mn
Mar 31, 2021 8.99 Mn
Dec 31, 2020 -1.25 Mn
Sep 30, 2020 5.44 Mn
Jun 30, 2020 -46,173.00
Mar 31, 2020 -621,567.00
Dec 31, 2019 8.72 Mn
Sep 30, 2019 -635,288.00
Jun 30, 2019 -751,236.00
Mar 31, 2019 -1.01 Mn
Dec 31, 2018 -725,493.00
Sep 30, 2018 -600,376.00
Jun 30, 2018 -754,435.00
Mar 31, 2018 -808,849.00
Dec 31, 2017 -806,020.00
Sep 30, 2017 6.31 Mn
Jun 30, 2017 729,912.00
Mar 31, 2017 678,516.00