Monopar Therapeutics (MNPR) Change in Cash (2017 - 2025)
Monopar Therapeutics' (MNPR) quarterly Change in Cash came in at -$65.8 million in Q4 2025, down 265.45% year-on-year from $39.8 million in Q4 2024, and down 174.67% quarter-over-quarter from $88.2 million in Q3 2025.
Monopar Therapeutics (MNPR) Change in Cash (2017 - 2025) Analysis & Trends
Monopar Therapeutics has disclosed Change in Cash across 9 years of filings, most recently posting -$65.8 million for Q4 2025.
- Change in Cash for Q4 2025 came in at -$65.8 million, down 265.45% year-over-year; the trailing twelve-month figure through Dec 2025 was $16.0 million (down 58.45% YoY), and the FY2025 annual result was $16.0 million, down 58.45% from the prior year.
- Change in Cash came in at -$65.8 million for Q4 2025 at Monopar Therapeutics, down from $88.2 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $88.2 million in Q3 2025 to a low of -$65.8 million in Q4 2025.
- The 5-year median for Change in Cash is -$1.6 million (2021), against an average of $2.3 million.
- Across the five-year window, Change in Cash slumped 2997.62% in 2021 and surged 88410.54% in 2025, its largest moves.
- Monopar Therapeutics' Change in Cash stood at -$2.0 million in 2021, then plunged by 200.84% to -$6.1 million in 2022, then jumped by 128.56% to $1.8 million in 2023, then jumped by 2173.12% to $39.8 million in 2024, then plunged by 265.45% to -$65.8 million in 2025.
- The last three Change in Cash figures came in at -$65.8 million (Q4 2025), $88.2 million (Q3 2025), and -$209473.0 (Q2 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 814,307.08 Bn | 814,307.05 Bn | - | - |
| 2 | Belite Bio | 55,320.00 Bn | 55,320.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,149.72 Bn | 17,149.72 Bn | - | 2.44 Mn |
| 4 | Legend Biotech | 3,590.00 Bn | 3,589.71 Bn | 242.10 Mn | 623.00 Mn |
| 5 | Akari Therapeutics | 1,650.72 Bn | 1,650.72 Bn | - | -2.44 Mn |
| 6 | Evaxion A | 1,522.09 Bn | 1,522.07 Bn | - | - |
| 7 | Psyence Biomedical | 229.39 Bn | 229.38 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 113.09 Bn | 105.85 Bn | 2.59 Bn | 417.10 Mn |
| 9 | Abivax | 90.15 Bn | 90.15 Bn | - | -45.97 Mn |
| 10 | Monopar Therapeutics | 441.25 Mn | 441.25 Mn | - | -65.84 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -65.84 Mn |
| Sep 30, 2025 | 88.18 Mn |
| Jun 30, 2025 | -209,473.00 |
| Mar 31, 2025 | -6.10 Mn |
| Dec 31, 2024 | 39.80 Mn |
| Sep 30, 2024 | -99,847.00 |
| Jun 30, 2024 | -1.69 Mn |
| Mar 31, 2024 | 541,499.00 |
| Dec 31, 2023 | 1.75 Mn |
| Sep 30, 2023 | -1.70 Mn |
| Jun 30, 2023 | 1.49 Mn |
| Mar 31, 2023 | -2.46 Mn |
| Dec 31, 2022 | -6.13 Mn |
| Sep 30, 2022 | -2.15 Mn |
| Jun 30, 2022 | -1.36 Mn |
| Mar 31, 2022 | -2.48 Mn |
| Dec 31, 2021 | -2.04 Mn |
| Sep 30, 2021 | -1.95 Mn |
| Jun 30, 2021 | -1.43 Mn |
| Mar 31, 2021 | 8.99 Mn |