Monopar Therapeutics (MNPR) Change in Cash (2017 - 2025)
Monopar Therapeutics (MNPR) reported Change in Cash of -$65.8 million for Q4 2025, down 265.45% on a YoY basis from $39.8 million in Q4 2024, and down 174.67% sequentially from $88.2 million in Q3 2025.
Monopar Therapeutics (MNPR) Change in Cash (2017 - 2025) Analysis & Trends
Monopar Therapeutics (MNPR) has 9 years of Change in Cash data on file, last reported at -$65.8 million in Q4 2025.
- For the quarter ending Q4 2025, Change in Cash fell 265.45% year-over-year to -$65.8 million; the trailing twelve-month figure through Dec 2025 stood at $16.0 million (down 58.45% YoY), and the FY2025 full-year result was $16.0 million, down 58.45% from the prior year.
- Change in Cash retreated to -$65.8 million in Q4 2025, from $88.2 million in the prior quarter.
- In the past five years, Change in Cash ranged from a high of $88.2 million in Q3 2025 to a low of -$65.8 million in Q4 2025.
- A 5-year average of $2.3 million and a median of -$1.6 million in 2021 frame the typical range for Change in Cash.
- Across the five-year window, Change in Cash plunged 2997.62% in 2021 and surged 88410.54% in 2025, its largest moves.
- Tracing MNPR's Change in Cash over 5 years: stood at -$2.0 million in 2021, then sank by 200.84% to -$6.1 million in 2022, then soared by 128.56% to $1.8 million in 2023, then soared by 2173.12% to $39.8 million in 2024, then sank by 265.45% to -$65.8 million in 2025.
- Business Quant data shows MNPR's Change in Cash at -$65.8 million in Q4 2025, $88.2 million in Q3 2025, and -$209473.0 in Q2 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Change in Cash (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -22.03 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 243.78 Mn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -1.34 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 417.10 Mn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -153.10 Mn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | - |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | 57.19 Mn |
| 10 | Monopar Therapeutics | 707.36 Mn | 645.53 Mn | - | -65.84 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Dec 31, 2025 | -65.84 Mn |
| Sep 30, 2025 | 88.18 Mn |
| Jun 30, 2025 | -209,473.00 |
| Mar 31, 2025 | -6.10 Mn |
| Dec 31, 2024 | 39.80 Mn |
| Sep 30, 2024 | -99,847.00 |
| Jun 30, 2024 | -1.69 Mn |
| Mar 31, 2024 | 541,499.00 |
| Dec 31, 2023 | 1.75 Mn |
| Sep 30, 2023 | -1.70 Mn |
| Jun 30, 2023 | 1.49 Mn |
| Mar 31, 2023 | -2.46 Mn |
| Dec 31, 2022 | -6.13 Mn |
| Sep 30, 2022 | -2.15 Mn |
| Jun 30, 2022 | -1.36 Mn |
| Mar 31, 2022 | -2.48 Mn |
| Dec 31, 2021 | -2.04 Mn |
| Sep 30, 2021 | -1.95 Mn |
| Jun 30, 2021 | -1.43 Mn |
| Mar 31, 2021 | 8.99 Mn |