Mineralys Therapeutics (MLYS) Net Cash Flow (2022 - 2026)

Quarterly results put Net Cash Flow at -$60.1 million for Q1 2026, down 218.12% from a year ago — trailing twelve months through Mar 2026 was -$52.2 million (down 170.02% YoY), and the annual figure for FY2025 was $58.8 million, down 9.19%.

Mineralys Therapeutics has reported Net Cash Flow over the past 5 years, most recently at -$60.1 million for Q1 2026.

  • Net Cash Flow reached -$60.1 million in Q1 2026 per MLYS's latest filing, down from -$44.7 million in the prior quarter.
  • Across five years, Net Cash Flow topped out at $115.9 million in Q3 2025 and bottomed at -$79.3 million in Q3 2022.
  • Median Net Cash Flow over the past 5 years was $5.4 million (2022), compared with a mean of $6.0 million.
  • The largest annual shift saw Net Cash Flow surged 832.74% in 2023 before it crashed 365.83% in 2025.
  • Over 5 years, Net Cash Flow stood at $38.7 million in 2022, then crashed by 195.48% to -$37.0 million in 2023, then soared by 145.46% to $16.8 million in 2024, then plummeted by 365.83% to -$44.7 million in 2025, then plummeted by 34.53% to -$60.1 million in 2026.
  • Business Quant data shows Net Cash Flow for MLYS at -$60.1 million in Q1 2026, -$44.7 million in Q4 2025, and $115.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Cash Flow (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.44 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 625.70 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 457.40 Mn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -152.20 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 60.68 Mn
10 Mineralys Therapeutics 2.50 Bn 2.50 Bn - -60.14 Mn

Historic Data

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DateValue
Mar 31, 2026 -60.14 Mn
Mar 31, 2026 -60.14 Mn
Dec 31, 2025 -44.70 Mn
Dec 31, 2025 -44.70 Mn
Sep 30, 2025 115.88 Mn
Sep 30, 2025 115.88 Mn
Jun 30, 2025 -63.26 Mn
Jun 30, 2025 -63.26 Mn
Mar 31, 2025 50.92 Mn
Mar 31, 2025 50.92 Mn
Dec 31, 2024 16.82 Mn
Dec 31, 2024 16.82 Mn
Sep 30, 2024 29.42 Mn
Sep 30, 2024 29.42 Mn
Jun 30, 2024 -22.56 Mn
Jun 30, 2024 -22.56 Mn
Mar 31, 2024 41.11 Mn
Mar 31, 2024 41.11 Mn
Dec 31, 2023 -37.00 Mn
Dec 31, 2023 -37.00 Mn
Sep 30, 2023 -14.84 Mn
Sep 30, 2023 -14.84 Mn
Jun 30, 2023 -37.11 Mn
Jun 30, 2023 -37.11 Mn
Mar 31, 2023 50.55 Mn
Mar 31, 2023 50.55 Mn
Dec 31, 2022 38.75 Mn
Dec 31, 2022 38.75 Mn
Sep 30, 2022 -79.31 Mn
Sep 30, 2022 -79.31 Mn
Jun 30, 2022 112.18 Mn
Jun 30, 2022 112.18 Mn
Mar 31, 2022 5.42 Mn
Mar 31, 2022 5.42 Mn