Mineralys Therapeutics (MLYS) Enterprise Value (2022 - 2026)

Mineralys Therapeutics (MLYS) posted Enterprise Value of -$644.9 million for Q1 2026, up 1.78% sequentially from -$656.6 million in Q4 2025, and down 88.02% YoY from -$5.4 billion in Q1 2025.

Mineralys Therapeutics (MLYS) Enterprise Value (2022 - 2026) Analysis & Trends

Mineralys Therapeutics has reported Enterprise Value for 5 years, with the latest figure at -$644.9 million in Q1 2026.

  • Quarterly Enterprise Value fell 88.02% year-over-year to -$644.9 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$644.9 million (down 88.02% YoY) and the FY2025 annual result came in at -$656.6 million, down 231.32% from the prior year.
  • Enterprise Value climbed to -$644.9 million in Q1 2026 per MLYS's latest filing, from -$656.6 million in the prior quarter.
  • Over five years, Enterprise Value peaked at -$110.1 million in Q4 2022 and troughed at -$656.6 million in Q4 2025.
  • A 5-year average of -$342.4 million and a median of -$289.4 million in 2023 frame the typical range for Enterprise Value.
  • The sharpest annual moves came in 2024 and 2025: Enterprise Value rose 16.22% in 2024, then sank 231.32% in 2025.
  • Over 5 years, Enterprise Value stood at -$110.1 million in 2022, then plunged by 114.85% to -$236.6 million in 2023, then grew by 16.22% to -$198.2 million in 2024, then tumbled by 231.32% to -$656.6 million in 2025, then rose by 1.78% to -$644.9 million in 2026.
  • According to Business Quant data, Enterprise Value over the past three periods registered -$644.9 million, -$656.6 million, and -$593.6 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn -7.85 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -7.99 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -5.18 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn - -3.94 Bn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn -5.10 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -8.46 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 2.12 Bn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -3.31 Bn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -1.16 Bn
10 Mineralys Therapeutics 2.27 Bn 1.60 Bn - -661.41 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -661.41 Mn
Mar 31, 2026 -644.93 Mn
Dec 31, 2025 -656.64 Mn
Sep 30, 2025 -593.63 Mn
Jun 30, 2025 -323.88 Mn
Mar 31, 2025 -343.01 Mn
Dec 31, 2024 -198.19 Mn
Sep 30, 2024 -263.60 Mn
Jun 30, 2024 -311.02 Mn
Mar 31, 2024 -338.57 Mn
Dec 31, 2023 -236.57 Mn
Sep 30, 2023 -252.41 Mn
Jun 30, 2023 -253.46 Mn
Mar 31, 2023 -267.73 Mn
Dec 31, 2022 -110.11 Mn