Mineralys Therapeutics (MLYS) Change in Cash (2022 - 2026)

Quarterly results put Change in Cash at -$60.1 million for Q1 2026, down 218.12% from a year ago — trailing twelve months through Mar 2026 was -$52.2 million (down 170.02% YoY), and the annual figure for FY2025 was $58.8 million, down 9.19%.

Mineralys Therapeutics has reported Change in Cash over the past 5 years, most recently at -$60.1 million for Q1 2026.

  • Change in Cash reached -$60.1 million in Q1 2026 per MLYS's latest filing, down from -$44.7 million in the prior quarter.
  • Across five years, Change in Cash topped out at $115.8 million in Q3 2025 and bottomed at -$79.3 million in Q3 2022.
  • Median Change in Cash over the past 5 years was $5.4 million (2022), compared with a mean of $6.0 million.
  • The largest annual shift saw Change in Cash surged 832.74% in 2023 before it crashed 365.66% in 2025.
  • Over 5 years, Change in Cash stood at $38.7 million in 2022, then crashed by 195.48% to -$37.0 million in 2023, then soared by 145.46% to $16.8 million in 2024, then plummeted by 365.66% to -$44.7 million in 2025, then crashed by 34.62% to -$60.1 million in 2026.
  • Business Quant data shows Change in Cash for MLYS at -$60.1 million in Q1 2026, -$44.7 million in Q4 2025, and $115.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Quantum Biopharma 1,384,976.65 Bn 1,384,976.64 Bn - 2.44 Mn
2 Alterity Therapeutics 777,208.84 Bn 777,208.81 Bn - -
3 Legend Biotech 2,801.00 Bn 2,800.10 Bn 242.10 Mn 623.00 Mn
4 Nanobiotix 2,226.01 Bn 2,225.95 Bn - -
5 Akari Therapeutics 605.66 Bn 605.66 Bn - -2.44 Mn
6 Vertex Pharmaceuticals 110.17 Bn 102.92 Bn 2.59 Bn 417.10 Mn
7 Regeneron Pharmaceuticals 66.86 Bn 58.11 Bn 3.31 Bn -153.10 Mn
8 Evaxion A 65.12 Bn 65.10 Bn - -
9 Alnylam Pharmaceuticals 39.94 Bn 36.94 Bn 959.66 Mn 53.61 Mn
10 Mineralys Therapeutics 2.50 Bn 2.50 Bn - -60.14 Mn

Historic Data

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DateValue
Mar 31, 2026 -60.14 Mn
Dec 31, 2025 -44.68 Mn
Sep 30, 2025 115.81 Mn
Jun 30, 2025 -63.22 Mn
Mar 31, 2025 50.92 Mn
Dec 31, 2024 16.82 Mn
Sep 30, 2024 29.42 Mn
Jun 30, 2024 -22.56 Mn
Mar 31, 2024 41.11 Mn
Dec 31, 2023 -37.00 Mn
Sep 30, 2023 -14.84 Mn
Jun 30, 2023 -37.11 Mn
Mar 31, 2023 50.55 Mn
Dec 31, 2022 38.75 Mn
Sep 30, 2022 -79.31 Mn
Jun 30, 2022 112.18 Mn
Mar 31, 2022 5.42 Mn