Mirum Pharmaceuticals (MIRM) Return on Sales [ROS] (2021 - 2026)
Mirum Pharmaceuticals' Return on Sales [ROS] was -24.14% in Q2 2026, down 20.23 percentage points from -3.90% a year earlier but up 469.64 percentage points from the prior quarter.
Mirum Pharmaceuticals (MIRM) Return on Sales [ROS] (2021 - 2026) Analysis & Trends
On a trailing twelve-month basis, Mirum Pharmaceuticals' Return on Sales [ROS] was -134.93% through Jun 30, 2026, down 121.63 percentage points year-over-year; for FY2025, it came in at -4.25%, up 21.76 percentage points from FY2024.
- Return on Sales [ROS] has now increased for four consecutive years, with a four-year change of +901.87 percentage points (FY2021 to FY2025).
- In earlier years, Return on Sales [ROS] was -26.00% in FY2024 (+32.56 pp), -58.57% in FY2023 (+111.71 pp), -170.28% in FY2022 (+735.84 pp) and -906.12% in FY2021.
- Quarterly Return on Sales [ROS] has moved between -1452.36% (Q4 2021) and 1.96% (Q3 2025) over five years.
- Compared with a year earlier, Return on Sales [ROS] was higher in six of the last eight quarters, with an average year-over-year change of -43.77 percentage points.
- The best year-over-year quarter for Return on Sales [ROS] over five years was Q4 2022 (a gain of 1329.94 percentage points); the worst was Q1 2026 (a drop of 480.17 percentage points).
- Per Business Quant data, MIRM's Return on Sales [ROS] in the three quarters before Q2 2026 was -493.78% (Q1 2026), -3.07% (Q4 2025) and 1.96% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 28.37% |
| 10 | Mirum Pharmaceuticals | 5.37 Bn | 3.79 Bn | 145.90 Mn | -24.14% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -24.14% |
| Mar 31, 2026 | -493.78% |
| Dec 31, 2025 | -3.07% |
| Sep 30, 2025 | 1.96% |
| Jun 30, 2025 | -3.90% |
| Mar 31, 2025 | -13.61% |
| Dec 31, 2024 | -24.36% |
| Sep 30, 2024 | -14.03% |
| Jun 30, 2024 | -31.12% |
| Mar 31, 2024 | -38.24% |
| Dec 31, 2023 | -46.85% |
| Sep 30, 2023 | -52.69% |
| Jun 30, 2023 | -64.73% |
| Mar 31, 2023 | -85.92% |
| Dec 31, 2022 | -122.41% |
| Sep 30, 2022 | -175.09% |
| Jun 30, 2022 | -179.83% |
| Mar 31, 2022 | -253.92% |
| Dec 31, 2021 | -1,452.36% |
| Sep 30, 2021 | -856.48% |
Mirum Pharmaceuticals Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MIRM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "MIRM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MIRM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();