Mirum Pharmaceuticals (MIRM) Return on Sales [ROS] (2019 - 2026)
Mirum Pharmaceuticals' Return on Sales [ROS] was -32.17% in Q3 2026, down 34.13 percentage points from 1.96% a year earlier and down 8.03 percentage points from the prior quarter.
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Analysis
Mirum Pharmaceuticals (MIRM) Return on Sales [ROS] (2019 - 2026) Analysis & Trends
On a trailing twelve-month basis, Mirum Pharmaceuticals' Return on Sales [ROS] was -133.62% through Sep 30, 2026, down 124.77 percentage points year-over-year; for FY2025, it came in at -4.25%, up 21.76 percentage points from FY2024.
- Return on Sales [ROS] has now increased for four consecutive years, with a four-year change of +901.87 percentage points (FY2021 to FY2025).
- In earlier years, Return on Sales [ROS] was -26.00% in FY2024 (+32.56 pp), -58.57% in FY2023 (+111.71 pp), -170.28% in FY2022 (+735.84 pp) and -906.12% in FY2021.
- Quarterly Return on Sales [ROS] has moved between -1452.36% (Q4 2021) and 1.96% (Q3 2025) over five years.
- Compared with a year earlier, Return on Sales [ROS] has declined for three straight quarters, with an average year-over-year change of -52.86 percentage points over the last eight quarters.
- The best year-over-year quarter for Return on Sales [ROS] over five years was Q4 2022 (a gain of 1329.94 percentage points); the worst was Q1 2026 (a drop of 480.17 percentage points).
- Per Business Quant data, MIRM's Return on Sales [ROS] in the three quarters before Q3 2026 was -24.14% (Q2 2026), -493.78% (Q1 2026) and -3.07% (Q4 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Mirum Pharmaceuticals | 6.16 Bn | 4.58 Bn | 150.55 Mn | -32.17% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | -32.17% |
| Jun 30, 2026 | -24.14% |
| Mar 31, 2026 | -493.78% |
| Dec 31, 2025 | -3.07% |
| Sep 30, 2025 | 1.96% |
| Jun 30, 2025 | -3.90% |
| Mar 31, 2025 | -13.61% |
| Dec 31, 2024 | -24.36% |
| Sep 30, 2024 | -14.03% |
| Jun 30, 2024 | -31.12% |
| Mar 31, 2024 | -38.24% |
| Dec 31, 2023 | -46.85% |
| Sep 30, 2023 | -52.69% |
| Jun 30, 2023 | -64.73% |
| Mar 31, 2023 | -85.92% |
| Dec 31, 2022 | -122.41% |
| Sep 30, 2022 | -175.09% |
| Jun 30, 2022 | -179.83% |
| Mar 31, 2022 | -253.92% |
| Dec 31, 2021 | -1,452.36% |
API Access
Mirum Pharmaceuticals Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MIRM&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "MIRM", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MIRM&period=max&api_key=YOUR_API_KEY");
const data = await res.json();