Growth Metrics

MeiraGTx Holdings (MGTX) EBITDA Margin (2019 - 2025)

MeiraGTx Holdings posted quarterly EBITDA Margin of 31.59% for Q4 2025, up 21050.0% year-on-year from N/an in Q4 2024, and up 100.26% on a QoQ basis from 12024.39% in Q3 2025.

MeiraGTx Holdings (MGTX) has 7 years of EBITDA Margin data on file, last reported at 31.59% in Q4 2025.

  • For the quarter ending Q4 2025, EBITDA Margin rose 21050.0% year-over-year to 31.59%; the trailing twelve-month figure through Dec 2025 stood at 107.16% (up 34380.0% YoY), and the FY2025 full-year result was 132.79%, up 31817.0% from the prior year.
  • EBITDA Margin for Q4 2025 stood at 31.59%, up from 12024.39% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 693.21% in Q4 2022 and bottomed at 17414.18% in Q2 2024.
  • The 5-year median for EBITDA Margin is 516.83% (2022), against an average of 2014.99%.
  • The widest annual swing landed in 2024, when EBITDA Margin plunged 1650678 bps; it then jumped 1629649 bps in 2025.
  • A 5-year view of EBITDA Margin shows it stood at 45.99% in 2021, then surged by 1607 bps to 693.21% in 2022, then slipped by 18 bps to 569.61% in 2023, then sank by 131 bps to 178.92% in 2024, then soared by 118 bps to 31.59% in 2025.
  • The last three EBITDA Margin figures came in at 31.59% (Q4 2025), 12024.39% (Q3 2025), and 1117.69% (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -6.43%
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 38.10%
7 Evaxion A 64.16 Bn 64.14 Bn - -
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 18.35%
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 17.24%
10 MeiraGTx Holdings 856.58 Mn 790.65 Mn 74.89 Mn 31.59%

Historic Data

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DateValue
Dec 31, 2025 31.59%
Sep 30, 2025 -12,024.39%
Jun 30, 2025 -1,117.69%
Dec 31, 2024 -178.92%
Sep 30, 2024 -371.81%
Jun 30, 2024 -17,414.18%
Mar 31, 2024 -3,175.47%
Dec 31, 2023 569.61%
Sep 30, 2023 -750.34%
Jun 30, 2023 -907.40%
Mar 31, 2023 -981.31%
Dec 31, 2022 693.21%
Sep 30, 2022 -592.03%
Jun 30, 2022 -247.38%
Mar 31, 2022 -516.83%
Dec 31, 2021 -45.99%
Sep 30, 2021 -335.00%
Jun 30, 2021 -400.57%
Mar 31, 2021 -519.87%
Dec 31, 2020 -367.11%
Sep 30, 2020 -207.25%
Jun 30, 2020 -1,006.47%
Mar 31, 2020 -278.74%
Dec 31, 2019 -139.26%
Sep 30, 2019 -245.84%
Jun 30, 2019 -971.02%
Mar 31, 2019 -2,435.23%