Growth Metrics

MeiraGTx Holdings (MGTX) EBITDA (2017 - 2025)

MeiraGTx Holdings posted quarterly EBITDA of $23.8 million for Q4 2025, up 162.21% year-on-year from $9.1 million in Q4 2024, and up 148.29% on a QoQ basis from -$49.3 million in Q3 2025.

MeiraGTx Holdings (MGTX) has 9 years of EBITDA data on file, last reported at $23.8 million in Q4 2025.

  • For the quarter ending Q4 2025, EBITDA rose 162.21% year-over-year to $23.8 million; the trailing twelve-month figure through Dec 2025 stood at -$108.1 million (up 27.99% YoY), and the FY2025 full-year result was -$108.1 million, up 27.99% from the prior year.
  • EBITDA for Q4 2025 stood at $23.8 million, up from -$49.3 million in the prior quarter.
  • Across five years, EBITDA topped out at $23.8 million in Q4 2025 and bottomed at -$49.3 million in Q3 2025.
  • The 5-year median for EBITDA is -$30.6 million (2022), against an average of -$27.4 million.
  • The widest annual swing landed in 2024, when EBITDA sank 429.35%; it then jumped 162.21% in 2025.
  • A 5-year view of EBITDA shows it stood at -$9.7 million in 2021, then sank by 278.81% to -$36.7 million in 2022, then surged by 131.7% to $11.6 million in 2023, then tumbled by 429.35% to -$38.3 million in 2024, then soared by 162.21% to $23.8 million in 2025.
  • The last three EBITDA figures came in at $23.8 million (Q4 2025), -$49.3 million (Q3 2025), and -$41.3 million (Q2 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 MeiraGTx Holdings 856.58 Mn 790.65 Mn 74.89 Mn 23.81 Mn

Historic Data

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DateValue
Dec 31, 2025 23.81 Mn
Sep 30, 2025 -49.30 Mn
Jun 30, 2025 -41.25 Mn
Mar 31, 2025 -41.33 Mn
Dec 31, 2024 -38.27 Mn
Sep 30, 2024 -40.56 Mn
Jun 30, 2024 -49.11 Mn
Mar 31, 2024 -22.13 Mn
Dec 31, 2023 11.62 Mn
Sep 30, 2023 -38.29 Mn
Jun 30, 2023 -32.12 Mn
Mar 31, 2023 -32.72 Mn
Dec 31, 2022 -36.66 Mn
Sep 30, 2022 -28.51 Mn
Jun 30, 2022 -26.62 Mn
Mar 31, 2022 -29.11 Mn
Dec 31, 2021 -9.68 Mn
Sep 30, 2021 -23.28 Mn
Jun 30, 2021 -20.49 Mn
Mar 31, 2021 -23.89 Mn
Dec 31, 2020 -13.91 Mn
Sep 30, 2020 -10.55 Mn
Jun 30, 2020 -24.90 Mn
Mar 31, 2020 -11.74 Mn
Dec 31, 2019 -9.67 Mn
Sep 30, 2019 -8.81 Mn
Jun 30, 2019 -19.24 Mn
Mar 31, 2019 -19.12 Mn
Dec 31, 2018 -20.47 Mn
Sep 30, 2018 -14.92 Mn
Jun 30, 2018 -28.00 Mn
Mar 31, 2018 -17.16 Mn
Dec 31, 2017 -9.14 Mn
Sep 30, 2017 -8.79 Mn
Jun 30, 2017 -7.52 Mn