Macrogenics (MGNX) Gross Profit (2020 - 2026)
Macrogenics (MGNX) posted quarterly Gross Profit of $41.2 million for Q4 2025, up 3.67% year-over-year from $39.8 million in Q4 2024, and down 43.4% quarter-over-quarter from $72.8 million in Q3 2025.
Analysis
Macrogenics (MGNX) Gross Profit (2020 - 2026) Analysis & Trends
Macrogenics (MGNX) has reported Gross Profit for 6 consecutive years, with $41.2 million the latest figure, recorded in Q4 2025.
- In Q4 2025, Gross Profit rose 3.67% year-over-year to $41.2 million; the TTM figure through Dec 2025 stood at $149.5 million (down 11.94% YoY), while the FY2025 annual figure was $149.5 million, changed 0.26% from the prior year.
- Gross Profit fell to $41.2 million in Q4 2025 per MGNX's latest filing, from $72.8 million in the prior quarter.
- Across five years, Gross Profit topped out at $110.5 million in Q3 2024 and bottomed at $8.8 million in Q1 2024.
- Historically, Gross Profit has averaged $30.0 million across 5 years, with a median of $19.6 million in 2021.
- Annual changes were most pronounced in 2023 — Gross Profit sank 85.53% — and 2024, when it soared 971.96%.
- Macrogenics' Gross Profit stood at $13.2 million in 2021, then soared by 452.9% to $73.0 million in 2022, then tumbled by 85.53% to $10.6 million in 2023, then jumped by 276.69% to $39.8 million in 2024, then grew by 3.67% to $41.2 million in 2025.
- Business Quant data shows MGNX's Gross Profit at $41.2 million in Q4 2025, $72.8 million in Q3 2025, and $22.2 million in Q2 2025.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) |
|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.78 Bn | 130.92 Bn | 2.84 Bn |
| 2 | Regeneron Pharmaceuticals | 85.50 Bn | 77.51 Bn | 3.93 Bn |
| 3 | Argenx Se | 63.51 Bn | 58.32 Bn | 1.37 Bn |
| 4 | Moderna | 58.06 Bn | 52.92 Bn | 52.00 Mn |
| 5 | Revolution Medicines | 44.04 Bn | 44.04 Bn | - |
| 6 | BeOne Medicines | 40.04 Bn | 34.94 Bn | 1.53 Bn |
| 7 | Alnylam Pharmaceuticals | 35.45 Bn | 32.14 Bn | 992.69 Mn |
| 8 | Royalty Pharma | 28.41 Bn | 27.57 Bn | - |
| 9 | Insmed | 27.42 Bn | 26.26 Bn | 358.27 Mn |
| 10 | Macrogenics | 276.32 Mn | 162.41 Mn | - |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Mar 31, 2026 | 11.25 Mn |
| Dec 31, 2025 | 31.11 Mn |
| Sep 30, 2025 | 61.25 Mn |
| Jun 30, 2025 | -2.04 Mn |
| Mar 31, 2025 | 7.79 Mn |
| Dec 31, 2024 | 34.74 Mn |
| Sep 30, 2024 | 109.01 Mn |
| Jun 30, 2024 | 8.15 Mn |
| Mar 31, 2024 | 7.26 Mn |
| Dec 31, 2023 | 10.72 Mn |
| Sep 30, 2023 | 7.12 Mn |
| Jun 30, 2023 | 12.22 Mn |
| Mar 31, 2023 | 21.09 Mn |
| Dec 31, 2022 | 72.30 Mn |
| Sep 30, 2022 | 38.73 Mn |
| Jun 30, 2022 | 23.79 Mn |
| Mar 31, 2022 | 11.05 Mn |
| Dec 31, 2021 | 13.20 Mn |
| Sep 30, 2021 | 14.00 Mn |
| Jun 30, 2021 | 30.74 Mn |