Macrogenics (MGNX) Gross Profit (2020 - 2025)

Macrogenics' (MGNX) quarterly Gross Profit came in at $41.2 million in Q4 2025, up 3.67% year-on-year from $39.8 million in Q4 2024, and down 43.4% on a QoQ basis from $72.8 million in Q3 2025.

Macrogenics (MGNX) Gross Profit (2020 - 2025) Analysis & Trends

Macrogenics (MGNX) has 6 years of Gross Profit data on file, last reported at $41.2 million in Q4 2025.

  • On a quarterly basis, Gross Profit rose 3.67% year-over-year to $41.2 million in Q4 2025; TTM through Dec 2025 was $149.5 million, a 11.94% decrease from a year earlier, with the FY2025 full-year figure at $149.5 million, changed 0.26% from the prior year.
  • Gross Profit for Q4 2025 stood at $41.2 million, down from $72.8 million in the prior quarter.
  • Over the last five years, Gross Profit for MGNX reached as high as $110.5 million in Q3 2024 and fell as low as $8.8 million in Q1 2024.
  • Historically, Gross Profit has averaged $30.0 million across 5 years, with a median of $19.6 million in 2021.
  • Across the five-year window, Gross Profit tumbled 85.53% in 2023 and jumped 971.96% in 2024, its largest moves.
  • Year by year, Gross Profit stood at $13.2 million in 2021, then surged by 452.9% to $73.0 million in 2022, then tumbled by 85.53% to $10.6 million in 2023, then soared by 276.69% to $39.8 million in 2024, then rose by 3.67% to $41.2 million in 2025.
  • Per Business Quant data, the three most recent Gross Profit figures were $41.2 million in Q4 2025, $72.8 million in Q3 2025, and $22.2 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn
7 Belite Bio 61.40 Bn 61.40 Bn -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn
9 Revolution Medicines 37.37 Bn 37.37 Bn -
10 Macrogenics 230.64 Mn 164.12 Mn -

Historic Data

Download Data
DateValue
Dec 31, 2025 41.23 Mn
Dec 31, 2025 41.23 Mn
Sep 30, 2025 72.84 Mn
Sep 30, 2025 72.84 Mn
Jun 30, 2025 22.24 Mn
Jun 30, 2025 22.24 Mn
Mar 31, 2025 13.19 Mn
Mar 31, 2025 13.19 Mn
Dec 31, 2024 39.77 Mn
Dec 31, 2024 39.77 Mn
Sep 30, 2024 110.54 Mn
Sep 30, 2024 110.54 Mn
Jun 30, 2024 10.62 Mn
Jun 30, 2024 10.62 Mn
Mar 31, 2024 8.83 Mn
Mar 31, 2024 8.83 Mn
Dec 31, 2023 10.56 Mn
Dec 31, 2023 10.56 Mn
Sep 30, 2023 10.31 Mn
Sep 30, 2023 10.31 Mn