Madrigal Pharmaceuticals (MDGL) Return on Sales [ROS] (2009 - 2026)
Madrigal Pharmaceuticals' Return on Sales [ROS] came in at 12.98% for Q3 2026, up 52.66 percentage points from -39.68% a year earlier and up 28.44 percentage points from the prior quarter.
Madrigal Pharmaceuticals (MDGL) Return on Sales [ROS] (2009 - 2026) Analysis & Trends
Over the trailing twelve months to Sep 30, 2026, Madrigal Pharmaceuticals reported Return on Sales [ROS] of -10.69%, up 30.83 percentage points year-over-year; for FY2025, it came in at -31.31%, up 245.08 percentage points from FY2024.
- Going back by year, Return on Sales [ROS] was -276.39% in FY2024.
- The Q3 2026 figure represents the highest quarterly Return on Sales [ROS] in data going back to Q2 2010.
- Year-over-year, Return on Sales [ROS] has increased for six consecutive quarters, with an average year-over-year change of +228.21 percentage points over the last six quarters.
- Business Quant data shows MDGL's Return on Sales [ROS] at -15.46% (Q2 2026), -29.78% (Q1 2026) and -18.56% (Q4 2025) in the three quarters before Q3 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 34.46% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 36.01% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 30.74% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 29.12% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 35.79% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | 41.71% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 32.98% |
| 10 | Madrigal Pharmaceuticals | 12.65 Bn | 9.06 Bn | 393.45 Mn | 12.98% |
Historic Data
| Date | Value |
|---|---|
| Sep 30, 2026 | 12.98% |
| Jun 30, 2026 | -15.46% |
| Mar 31, 2026 | -29.78% |
| Dec 31, 2025 | -18.56% |
| Sep 30, 2025 | -39.68% |
| Jun 30, 2025 | -22.18% |
| Mar 31, 2025 | -57.79% |
| Dec 31, 2024 | -64.84% |
| Sep 30, 2024 | -187.06% |
| Jun 30, 2024 | -1,110.38% |
| Dec 31, 2019 | -43,968.52% |
| Sep 30, 2019 | -20,377.44% |
| Jun 30, 2019 | -13,819.50% |
| Dec 31, 2018 | -6,691.67% |
| Sep 30, 2018 | -6,513.22% |
| Jun 30, 2018 | -8,506.52% |
| Mar 31, 2018 | -9,301.32% |
| Sep 30, 2016 | -33,728.28% |
| Jun 30, 2016 | -13,889.47% |
| Dec 31, 2012 | -41,456.46% |
Madrigal Pharmaceuticals Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MDGL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "MDGL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MDGL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();