Madrigal Pharmaceuticals (MDGL) Return on Sales [ROS] (2010 - 2026)
Madrigal Pharmaceuticals' Return on Sales [ROS] came in at -15.46% for Q2 2026, up 6.72 percentage points from -22.18% a year earlier and up 14.32 percentage points from the prior quarter.
Madrigal Pharmaceuticals (MDGL) Return on Sales [ROS] (2010 - 2026) Analysis & Trends
Over the trailing twelve months to Jun 30, 2026, Madrigal Pharmaceuticals reported Return on Sales [ROS] of -25.13%, up 34.97 percentage points year-over-year; for FY2025, it came in at -31.31%, up 245.08 percentage points from FY2024.
- Going back by year, Return on Sales [ROS] was -276.39% in FY2024.
- The Q2 2026 figure represents the highest quarterly Return on Sales [ROS] in data going back to Q2 2010.
- Year-over-year, Return on Sales [ROS] has increased for five consecutive quarters, with an average year-over-year change of +263.32 percentage points over the last five quarters.
- Business Quant data shows MDGL's Return on Sales [ROS] at -29.78% (Q1 2026), -18.56% (Q4 2025) and -39.68% (Q3 2025) in the three quarters before Q2 2026.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,199.50 Bn | 1,168.08 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 635.17 Bn | 555.03 Bn | 17.30 Bn | 24.35% |
| 3 | AbbVie | 504.69 Bn | 477.85 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 358.43 Bn | 312.86 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 288.36 Bn | 252.75 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 265.78 Bn | 239.54 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 237.46 Bn | 192.86 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 193.65 Bn | 167.76 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 171.05 Bn | 118.00 Bn | 10.94 Bn | 28.37% |
| 10 | Madrigal Pharmaceuticals | 12.66 Bn | 8.91 Bn | - | -15.46% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -15.46% |
| Mar 31, 2026 | -29.78% |
| Dec 31, 2025 | -18.56% |
| Sep 30, 2025 | -39.68% |
| Jun 30, 2025 | -22.18% |
| Mar 31, 2025 | -57.79% |
| Dec 31, 2024 | -64.84% |
| Sep 30, 2024 | -187.06% |
| Jun 30, 2024 | -1,110.38% |
| Dec 31, 2019 | -227,325.39% |
| Sep 30, 2019 | -130,757.84% |
| Sep 30, 2016 | -33,728.28% |
| Jun 30, 2016 | -13,889.47% |
| Dec 31, 2012 | -41,456.46% |
| Sep 30, 2012 | -1,497.96% |
| Jun 30, 2012 | -977.38% |
| Mar 31, 2012 | -9,908.16% |
| Dec 31, 2011 | -299.12% |
| Sep 30, 2011 | -734.25% |
| Jun 30, 2011 | -886.93% |
Madrigal Pharmaceuticals Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MDGL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "MDGL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=MDGL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();