Madrigal Pharmaceuticals (MDGL) Research & Development (2010 - 2026)

Madrigal Pharmaceuticals' (MDGL) quarterly Research & Development came in at $108.7 million in Q1 2026, up 146.07% year-on-year from $44.2 million in Q1 2025, and down 6.52% on a QoQ basis from $116.3 million in Q4 2025.

Madrigal Pharmaceuticals (MDGL) Research & Development (2010 - 2026) Analysis & Trends

Madrigal Pharmaceuticals (MDGL) has 17 years of Research & Development data on file, last reported at $108.7 million in Q1 2026.

  • On a quarterly basis, Research & Development rose 146.07% year-over-year to $108.7 million in Q1 2026; TTM through Mar 2026 was $453.0 million, a 105.09% increase from a year earlier, with the FY2025 full-year figure at $388.5 million, up 64.13% from the prior year.
  • Research & Development for Q1 2026 stood at $108.7 million, down from $116.3 million in the prior quarter.
  • Over the last five years, Research & Development for MDGL reached as high as $174.0 million in Q3 2025 and fell as low as $36.9 million in Q4 2024.
  • Historically, Research & Development has averaged $74.3 million across 5 years, with a median of $68.7 million in 2024.
  • Across the five-year window, Research & Development slumped 47.76% in 2024 and surged 215.09% in 2025, its largest moves.
  • Year by year, Research & Development stood at $70.7 million in 2022, then retreated by 0.14% to $70.6 million in 2023, then slumped by 47.76% to $36.9 million in 2024, then jumped by 215.09% to $116.3 million in 2025, then fell by 6.52% to $108.7 million in 2026.
  • Per Business Quant data, the three most recent Research & Development figures were $108.7 million in Q1 2026, $116.3 million in Q4 2025, and $174.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -17.94 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 541.22 Mn
4 NuCana 279.75 Bn 279.75 Bn - -2.31 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 15.66 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 1.37 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 343.97 Mn
10 Madrigal Pharmaceuticals 15.77 Bn 15.54 Bn - 108.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 108.69 Mn
Dec 31, 2025 116.27 Mn
Sep 30, 2025 174.00 Mn
Jun 30, 2025 54.08 Mn
Mar 31, 2025 44.17 Mn
Dec 31, 2024 36.90 Mn
Sep 30, 2024 68.74 Mn
Jun 30, 2024 71.09 Mn
Mar 31, 2024 71.24 Mn
Dec 31, 2023 70.64 Mn
Sep 30, 2023 70.95 Mn
Jun 30, 2023 68.61 Mn
Mar 31, 2023 62.15 Mn
Dec 31, 2022 70.74 Mn
Sep 30, 2022 68.27 Mn
Jun 30, 2022 58.50 Mn
Mar 31, 2022 47.93 Mn
Dec 31, 2021 52.89 Mn
Sep 30, 2021 54.87 Mn
Jun 30, 2021 51.63 Mn