Madrigal Pharmaceuticals (MDGL) Net Margin (2010 - 2026)
Madrigal Pharmaceuticals (MDGL) reported Net Margin of 29.64% for Q1 2026, up 2372.0% year-over-year from 1.2% in Q1 2025, and down 62.83% quarter-over-quarter from 18.2% in Q4 2025.
Madrigal Pharmaceuticals (MDGL) Net Margin (2010 - 2026) Analysis & Trends
Madrigal Pharmaceuticals (MDGL) has 6 years of Net Margin data on file, last reported at 29.64% in Q1 2026.
- Net Margin for Q1 2026 came in at 29.64%, up 2372.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 26.85% (up 9653.0% YoY), and the FY2025 annual result was 29.74%, up 22890.0% from the prior year.
- Net Margin retreated to 29.64% in Q1 2026 per MDGL's latest filing, from 18.2% in the prior quarter.
- Over five years, Net Margin peaked at 18.2% in Q4 2025 and troughed at 1038.2% in Q2 2024.
- A 3-year average of 178.43% and a median of 46.02% in 2025 frame the typical range for Net Margin.
- The sharpest annual moves came in 2025 and 2026: Net Margin surged 101835 bps in 2025, then surged 2372 bps in 2026.
- A 3-year view of Net Margin shows it stood at 57.51% in 2024, then soared by 68 bps to 18.2% in 2025, then plunged by 63 bps to 29.64% in 2026.
- Business Quant data shows MDGL's Net Margin at 29.64% in Q1 2026, 18.2% in Q4 2025, and 38.68% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Madrigal Pharmaceuticals | 14.67 Bn | 14.44 Bn | - | -29.64% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -29.64% |
| Dec 31, 2025 | -18.20% |
| Sep 30, 2025 | -38.68% |
| Jun 30, 2025 | -19.85% |
| Mar 31, 2025 | -53.36% |
| Dec 31, 2024 | -57.51% |
| Sep 30, 2024 | -172.04% |
| Jun 30, 2024 | -1,038.20% |
| Mar 31, 2012 | -10,238.78% |
| Dec 31, 2011 | -313.85% |
| Sep 30, 2011 | -2,444.15% |
| Jun 30, 2011 | -5,925.12% |
| Mar 31, 2011 | -997.46% |
| Dec 31, 2010 | -218.55% |
| Sep 30, 2010 | -303.34% |
| Jun 30, 2010 | -270.06% |