Madrigal Pharmaceuticals (MDGL) Net Income (2010 - 2026)

Madrigal Pharmaceuticals' (MDGL) quarterly Net Income came in at -$92.3 million in Q1 2026, down 26.03% year-on-year from -$124.8 million in Q1 2025, and up 46.33% on a QoQ basis from -$172.0 million in Q4 2025.

Madrigal Pharmaceuticals (MDGL) Net Income (2010 - 2026) Analysis & Trends

Madrigal Pharmaceuticals (MDGL) has 17 years of Net Income data on file, last reported at -$92.3 million in Q1 2026.

  • On a quarterly basis, Net Income fell 26.03% year-over-year to -$92.3 million in Q1 2026; TTM through Mar 2026 was -$417.6 million, a 10.48% decrease from a year earlier, with the FY2025 full-year figure at -$853.8 million, up 11.07% from the prior year.
  • Net Income for Q1 2026 stood at -$92.3 million, up from -$172.0 million in the prior quarter.
  • Over the last five years, Net Income for MDGL reached as high as -$42.2 million in Q2 2025 and fell as low as -$172.0 million in Q4 2025.
  • Historically, Net Income has averaged -$94.8 million across 5 years, with a median of -$85.9 million in 2022.
  • On a YoY basis, Net Income climbed as much as 72.21% in 2025 and fell as far as 275.12% in 2025.
  • Year by year, Net Income stood at -$85.9 million in 2022, then sank by 30.6% to -$112.2 million in 2023, then surged by 59.14% to -$45.8 million in 2024, then tumbled by 275.12% to -$172.0 million in 2025, then soared by 46.33% to -$92.3 million in 2026.
  • Per Business Quant data, the three most recent Net Income figures were -$92.3 million in Q1 2026, -$172.0 million in Q4 2025, and -$111.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 67,102.16 Bn 67,101.87 Bn - -37.09 Mn
2 Nanobiotix 1,908.96 Bn 1,908.90 Bn - -
3 Akari Therapeutics 959.56 Bn 959.56 Bn - -14.46 Mn
4 BeOne Medicines 474.03 Bn 469.24 Bn 1.35 Bn 227.36 Mn
5 Vertex Pharmaceuticals 122.13 Bn 114.88 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 70.09 Bn 61.34 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.34 Bn 62.34 Bn - -26.94 Mn
8 Argenx Se 55.96 Bn 50.77 Bn 1.41 Bn 362.00 Mn
9 Alnylam Pharmaceuticals 37.53 Bn 34.52 Bn 959.66 Mn 205.99 Mn
10 Madrigal Pharmaceuticals 16.09 Bn 15.86 Bn - -92.30 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -92.30 Mn
Dec 31, 2025 -171.98 Mn
Sep 30, 2025 -111.12 Mn
Jun 30, 2025 -42.24 Mn
Mar 31, 2025 -73.24 Mn
Dec 31, 2024 -45.85 Mn
Sep 30, 2024 -106.96 Mn
Jun 30, 2024 -151.97 Mn
Mar 31, 2024 -147.54 Mn
Dec 31, 2023 -112.19 Mn
Sep 30, 2023 -98.74 Mn
Jun 30, 2023 -85.80 Mn
Mar 31, 2023 -76.90 Mn
Dec 31, 2022 -85.91 Mn
Sep 30, 2022 -81.20 Mn
Jun 30, 2022 -70.73 Mn
Mar 31, 2022 -57.52 Mn
Dec 31, 2021 -64.55 Mn
Sep 30, 2021 -63.10 Mn
Jun 30, 2021 -61.65 Mn