Lyell Immunopharma (LYEL) Return on Equity [ROE] (2021 - 2026)
Lyell Immunopharma's Return on Equity [ROE] came in at -101.09% for Q2 2026, up 11.01 percentage points from -112.10% a year earlier but down 2.86 percentage points from the prior quarter.
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Analysis
Lyell Immunopharma (LYEL) Return on Equity [ROE] (2021 - 2026) Analysis & Trends
For FY2025, Lyell Immunopharma's Return on Equity [ROE] was -85.39%, down 16.25 percentage points from FY2024.
- Return on Equity [ROE] has declined in each of the last three years, with a four-year change of -17.98 percentage points (FY2021 to FY2025).
- Going back by year, Return on Equity [ROE] was -69.14% in FY2024 (-35.94 pp), -33.20% in FY2023 (-11.98 pp), -21.22% in FY2022 (+46.19 pp) and -67.41% in FY2021.
- The five-year range for quarterly Return on Equity [ROE] is -112.10% (Q2 2025) to -20.54% (Q3 2021).
- Year-over-year, Return on Equity [ROE] increased in two of the last eight quarters, with an average year-over-year change of -32.55 percentage points.
- The fastest year-over-year change in Return on Equity [ROE] over five years came in Q2 2022 (a gain of 33.02 percentage points), and the weakest in Q2 2025 (a drop of 73.51 percentage points).
- Business Quant data shows LYEL's Return on Equity [ROE] at -98.22% (Q1 2026), -93.33% (Q4 2025) and -109.20% (Q3 2025) in the three quarters before Q2 2026.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROE (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 25.32% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | - |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 7.21% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 84.40% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 21.39% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 83.75% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -18.38% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 4.97% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 22.24% |
| 10 | Lyell Immunopharma | 229.06 Mn | 229.06 Mn | - | -101.09% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -101.09% |
| Mar 31, 2026 | -98.22% |
| Dec 31, 2025 | -93.33% |
| Sep 30, 2025 | -109.20% |
| Jun 30, 2025 | -112.10% |
| Mar 31, 2025 | -100.24% |
| Dec 31, 2024 | -78.54% |
| Sep 30, 2024 | -39.58% |
| Jun 30, 2024 | -38.58% |
| Mar 31, 2024 | -38.16% |
| Dec 31, 2023 | -36.53% |
| Sep 30, 2023 | -28.20% |
| Jun 30, 2023 | -27.58% |
| Mar 31, 2023 | -22.39% |
| Dec 31, 2022 | -22.63% |
| Sep 30, 2022 | -26.04% |
| Jun 30, 2022 | -23.13% |
| Mar 31, 2022 | -25.12% |
| Dec 31, 2021 | -22.37% |
| Sep 30, 2021 | -20.54% |
API Access
Lyell Immunopharma Return on Equity [ROE] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LYEL&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-equity-[roe]", "ticker": "LYEL", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=LYEL&period=max&api_key=YOUR_API_KEY");
const data = await res.json();