Lexeo Therapeutics (LXEO) Return on Capital Employed (2023 - 2026)

Lexeo Therapeutics' (LXEO) quarterly Return on Capital Employed came in at 39.86% in Q1 2026, down 1030.0% year-on-year from 4.29% in Q1 2025, and up 30.88% quarter-over-quarter from 57.67% in Q4 2025.

Lexeo Therapeutics (LXEO) Return on Capital Employed (2023 - 2026) Analysis & Trends

Lexeo Therapeutics has disclosed Return on Capital Employed across 4 years of filings, most recently posting 39.86% for Q1 2026.

  • Return on Capital Employed for Q1 2026 came in at 39.86%, down 1030.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 39.86% (down 1030.0% YoY), and the FY2025 annual result was 57.2%, down 4005.0% from the prior year.
  • Return on Capital Employed came in at 39.86% for Q1 2026 at Lexeo Therapeutics, up from 57.67% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 15.03% in Q4 2024 to a low of 85.61% in Q4 2023.
  • The 4-year median for Return on Capital Employed is 42.27% (2024), against an average of 43.11%.
  • Across the five-year window, Return on Capital Employed surged 7058 bps in 2024 and slumped 4264 bps in 2025, its largest moves.
  • Lexeo Therapeutics' Return on Capital Employed stood at 85.61% in 2023, then soared by 82 bps to 15.03% in 2024, then tumbled by 284 bps to 57.67% in 2025, then jumped by 31 bps to 39.86% in 2026.
  • The last three Return on Capital Employed figures came in at 39.86% (Q1 2026), 57.67% (Q4 2025), and 19.92% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 450.31%
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 51.73%
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -107.40%
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 21.10%
9 Abivax 91.96 Bn 91.96 Bn - -50.43%
10 Lexeo Therapeutics 405.92 Mn 212.88 Mn - -39.86%

Historic Data

Download Data
DateValue
Mar 31, 2026 -39.86%
Dec 31, 2025 -57.67%
Sep 30, 2025 -19.92%
Jun 30, 2025 -32.13%
Mar 31, 2025 -29.56%
Dec 31, 2024 -15.03%
Sep 30, 2024 -59.80%
Jun 30, 2024 -44.68%
Mar 31, 2024 -46.82%
Dec 31, 2023 -85.61%